Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework
Ollier, Romain, Fuchs, Aline, Gauye, Florence, Piorkowska, Katarzyna, Menant, Sébastien, Ratnam, Monisha, Montanari, Paolo, Guilhot, Florence, Phillipe, Didier, Audrain, Mickael, Egesipe, Anne-Laure, Névoltris, Damien, Seredenina, Tamara, Pfeifer, Andrea, Kosco-Vilbois, Marie, Afroz, Tariq
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation
Scholler, Pauline, Nevoltris, Damien, de Bundel, Dimitri, Bossi, Simon, Moreno-Delgado, David, Rovira, Xavier, Møller, Thor C., El Moustaine, Driss, Mathieu, Michaël, Blanc, Emilie, McLean, Heather, Dupuis, Elodie, Mathis, Gérard, Trinquet, Eric, Daniel, Hervé, Valjent, Emmanuel, Baty, Daniel, Chames, Patrick, Rondard, Philippe, Pin, Jean-Philippe
Published in Nature communications (06.12.2017)
Published in Nature communications (06.12.2017)
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Systematic functional identification of cancer multi-drug resistance genes
Lau, Man-Tat, Ghazanfar, Shila, Parkin, Ashleigh, Chou, Angela, Rouaen, Jourdin R, Littleboy, Jamie B, Nessem, Danielle, Khuong, Thang M, Nevoltris, Damien, Schofield, Peter, Langley, David, Christ, Daniel, Yang, Jean, Pajic, Marina, Neely, G Gregory
Published in Genome Biology (07.02.2020)
Published in Genome Biology (07.02.2020)
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Journal Article
Force measurements of TCR/pMHC recognition at T cell surface
Puech, Pierre-Henri, Nevoltris, Damien, Robert, Philippe, Limozin, Laurent, Boyer, Claude, Bongrand, Pierre
Published in PloS one (22.07.2011)
Published in PloS one (22.07.2011)
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Journal Article
Transient expression of human antibodies in mammalian cells
Vazquez-Lombardi, Rodrigo, Nevoltris, Damien, Luthra, Ansha, Schofield, Peter, Zimmermann, Carsten, Christ, Daniel
Published in Nature protocols (01.01.2018)
Published in Nature protocols (01.01.2018)
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Journal Article
In vivo detection of small tumour lesions by multi-pinhole SPECT applying a (99m)Tc-labelled nanobody targeting the Epidermal Growth Factor Receptor
Krüwel, Thomas, Nevoltris, Damien, Bode, Julia, Dullin, Christian, Baty, Daniel, Chames, Patrick, Alves, Frauke
Published in Scientific reports (25.02.2016)
Published in Scientific reports (25.02.2016)
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Journal Article
In vivo detection of small tumour lesions by multi-pinhole SPECT applying a 99mTc-labelled nanobody targeting the Epidermal Growth Factor Receptor
Krüwel, Thomas, Nevoltris, Damien, Bode, Julia, Dullin, Christian, Baty, Daniel, Chames, Patrick, Alves, Frauke
Published in Scientific reports (25.02.2016)
Published in Scientific reports (25.02.2016)
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Journal Article
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody
Singh, Mandeep, Jackson, Katherine J.L., Wang, Jing J., Schofield, Peter, Field, Matt A., Koppstein, David, Peters, Timothy J., Burnett, Deborah L., Rizzetto, Simone, Nevoltris, Damien, Masle-Farquhar, Etienne, Faulks, Megan L., Russell, Amanda, Gokal, Divya, Hanioka, Asami, Horikawa, Keisuke, Colella, Alexander D., Chataway, Timothy K., Blackburn, James, Mercer, Tim R., Langley, David B., Goodall, D. Margaret, Jefferis, Roy, Gangadharan Komala, Muralikrishna, Kelleher, Anthony D., Suan, Dan, Rischmueller, Maureen, Christ, Daniel, Brink, Robert, Luciani, Fabio, Gordon, Tom P., Goodnow, Christopher C., Reed, Joanne H.
Published in Cell (05.03.2020)
Published in Cell (05.03.2020)
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Journal Article
A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers
Haubrich, Jordi, Font, Joan, Quast, Robert B, Goupil-Lamy, Anne, Scholler, Pauline, Nevoltris, Damien, Acher, Francine, Chames, Patrick, Rondard, Philippe, Prézeau, Laurent, Pin, Jean-Philippe
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2021)
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Journal Article
Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques
Eshak, Floriane, Pion, Léo, Scholler, Pauline, Nevoltris, Damien, Chames, Patrick, Rondard, Philippe, Pin, Jean-Philippe, Acher, Francine C., Goupil-Lamy, Anne
Published in Journal of chemical information and modeling (29.02.2024)
Published in Journal of chemical information and modeling (29.02.2024)
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Journal Article
A nanobody activating metabotropic glutamate receptor 4 discriminates between homoand heterodimers
Haubrich, Jordi, Font, Joan, Quast, Robert B., Goupil-Lamy, Anne, Scholler, Pauline, Nevoltris, Damien, Acher, Francine, Chames, Patrick, Rondard, Philippe, Prézeau, Laurent, Pin, Jean-Philippe
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2021)
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Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2021)
Journal Article
Genetic and structural basis of the human anti-α-galactosyl antibody response
Langley, David B, Schofield, Peter, Nevoltris, Damien, Jackson, Jennifer, Jackson, Katherine J L, Peters, Tim J, Burk, Melanie, Matthews, Jacqueline M, Basten, Antony, Goodnow, Christopher C, van Nunen, Sheryl, Reed, Joanne H, Christ, Daniel
Published in Proceedings of the National Academy of Sciences - PNAS (12.07.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (12.07.2022)
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Journal Article
Human Antibody Bispecifics through Phage Display Selection
Luthra, Ansha, Langley, David B, Schofield, Peter, Jackson, Jennifer, Abdelatti, Mahmoud, Rouet, Romain, Nevoltris, Damien, Mazigi, Ohan, Crossett, Ben, Christie, Mary, Christ, Daniel
Published in Biochemistry (Easton) (02.04.2019)
Published in Biochemistry (Easton) (02.04.2019)
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