Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force
Mykuliak, Vasyl V, Rahikainen, Rolle, Ball, Neil J, Bussi, Giovanni, Goult, Benjamin T, Hytönen, Vesa P
Published in PLoS computational biology (07.08.2024)
Published in PLoS computational biology (07.08.2024)
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Journal Article
Cancer associated talin point mutations disorganise cell adhesion and migration
Azizi, Latifeh, Cowell, Alana R., Mykuliak, Vasyl V., Goult, Benjamin T., Turkki, Paula, Hytönen, Vesa P.
Published in Scientific reports (11.01.2021)
Published in Scientific reports (11.01.2021)
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Journal Article
Talin-1 variants associated with spontaneous coronary artery dissection (SCAD) highlight how even subtle changes in multi-functional scaffold proteins can manifest in disease
Azizi, Latifeh, Otani, Yasumi, Mykuliak, Vasyl V, Goult, Benjamin T, Hytönen, Vesa P, Turkki, Paula
Published in Human molecular genetics (21.08.2024)
Published in Human molecular genetics (21.08.2024)
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Journal Article
Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway
Chronopoulos, Antonios, Thorpe, Stephen D., Cortes, Ernesto, Lachowski, Dariusz, Rice, Alistair J., Mykuliak, Vasyl V., Róg, Tomasz, Lee, David A., Hytönen, Vesa P., del Río Hernández, Armando E.
Published in Nature materials (01.06.2020)
Published in Nature materials (01.06.2020)
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Journal Article
Microfluidics‐Based Force Spectroscopy Enables High‐Throughput Force Experiments with Sub‐Nanometer Resolution and Sub‐Piconewton Sensitivity
Kerkhoff, Yannic, Azizi, Latifeh, Mykuliak, Vasyl V., Hytönen, Vesa P., Block, Stephan
Published in Small (Weinheim an der Bergstrasse, Germany) (01.04.2023)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.04.2023)
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Journal Article
Induction of ligand promiscuity of αVβ3 integrin by mechanical force
Bachmann, Michael, Schäfer, Markus, Mykuliak, Vasyl V, Ripamonti, Marta, Heiser, Lia, Weißenbruch, Kai, Krübel, Sarah, Franz, Clemens M, Hytönen, Vesa P, Wehrle-Haller, Bernhard, Bastmeyer, Martin
Published in Journal of cell science (11.05.2020)
Published in Journal of cell science (11.05.2020)
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Journal Article
Talin variant P229S compromises integrin activation and associates with multifaceted clinical symptoms
Azizi, Latifeh, Varela, Lorena, Turkki, Paula, Mykuliak, Vasyl V, Korpela, Sanna, Ihalainen, Teemu O, Church, Joseph, Hytönen, Vesa P, Goult, Benjamin T
Published in Human molecular genetics (16.12.2022)
Published in Human molecular genetics (16.12.2022)
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Journal Article
Biochemical and structural characterization of beta-carbonic anhydrase from the parasite Trichomonas vaginalis
Urbański, Linda J., Angeli, Andrea, Mykuliak, Vasyl V., Azizi, Latifeh, Kuuslahti, Marianne, Hytönen, Vesa P., Supuran, Claudiu T., Parkkila, Seppo
Published in Journal of molecular medicine (Berlin, Germany) (01.01.2022)
Published in Journal of molecular medicine (Berlin, Germany) (01.01.2022)
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Journal Article
Computational modeling and molecular dynamics simulations of mammalian cytoplasmic tyrosyl-tRNA synthetase and its complexes with substrates
Kravchuk, Vladyslav O., Savytskyi, Oleksandr V., Odynets, Konstantin O., Mykuliak, Vasyl V., Kornelyuk, Alexander I.
Published in Journal of biomolecular structure & dynamics (03.10.2017)
Published in Journal of biomolecular structure & dynamics (03.10.2017)
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Journal Article
Induction of ligand promiscuity of αVβ3 integrin by mechanical force
Bachmann, Michael, Schäfer, Markus, Mykuliak, Vasyl V, Ripamonti, Marta, Heiser, Lia, Weißenbruch, Kai, Krübel, Sarah, Franz, Clemens M, Hytönen, Vesa P, Wehrle-Haller, Bernhard, Bastmeyer, Martin
Published in Journal of cell science (01.01.2020)
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Published in Journal of cell science (01.01.2020)
Journal Article