Attenuation of multiple Nef functions in HIV-1 elite controllers
Mwimanzi, Philip, Markle, Tristan J, Martin, Eric, Ogata, Yoko, Kuang, Xiaomei T, Tokunaga, Michiyo, Mahiti, Macdonald, Pereyra, Florencia, Miura, Toshiyuki, Walker, Bruce D, Brumme, Zabrina L, Brockman, Mark A, Ueno, Takamasa
Published in Retrovirology (07.01.2013)
Published in Retrovirology (07.01.2013)
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Journal Article
Novel Acylguanidine-Based Inhibitor of HIV-1
Mwimanzi, Philip, Tietjen, Ian, Miller, Scott C, Shahid, Aniqa, Cobarrubias, Kyle, Kinloch, Natalie N, Baraki, Bemuluyigza, Richard, Jonathan, Finzi, Andrés, Fedida, David, Brumme, Zabrina L, Brockman, Mark A
Published in Journal of virology (15.10.2016)
Published in Journal of virology (15.10.2016)
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Journal Article
Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors
Tietjen, Ian, Ntie-Kang, Fidele, Mwimanzi, Philip, Onguéné, Pascal Amoa, Scull, Margaret A, Idowu, Thomas Oyebode, Ogundaini, Abiodun Oguntuga, Meva'a, Luc Mbaze, Abegaz, Berhanu M, Rice, Charles M, Andrae-Marobela, Kerstin, Brockman, Mark A, Brumme, Zabrina L, Fedida, David
Published in PloS one (01.04.2015)
Published in PloS one (01.04.2015)
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Journal Article
Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes
Mann, Jaclyn K, Byakwaga, Helen, Kuang, Xiaomei T, Le, Anh Q, Brumme, Chanson J, Mwimanzi, Philip, Omarjee, Saleha, Martin, Eric, Lee, Guinevere Q, Baraki, Bemuluyigza, Danroth, Ryan, McCloskey, Rosemary, Muzoora, Conrad, Bangsberg, David R, Hunt, Peter W, Goulder, Philip J R, Walker, Bruce D, Harrigan, P Richard, Martin, Jeff N, Ndung'u, Thumbi, Brockman, Mark A, Brumme, Zabrina L
Published in Retrovirology (16.09.2013)
Published in Retrovirology (16.09.2013)
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Journal Article
Dynamic range of Nef functions in chronic HIV-1 infection
Mwimanzi, Philip, Markle, Tristan J, Ogata, Yoko, Martin, Eric, Tokunaga, Michiyo, Mahiti, Macdonald, Kuang, Xiaomei T, Walker, Bruce D, Brockman, Mark A, Brumme, Zabrina L, Ueno, Takamasa
Published in Virology (New York, N.Y.) (10.05.2013)
Published in Virology (New York, N.Y.) (10.05.2013)
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Journal Article
CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef
Ueno, Takamasa, Motozono, Chihiro, Dohki, Sachi, Mwimanzi, Philip, Rauch, Susanne, Fackler, Oliver T, Oka, Shinichi, Takiguchi, Masafumi
Published in The Journal of immunology (1950) (15.01.2008)
Published in The Journal of immunology (1950) (15.01.2008)
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Journal Article
Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences
Mahiti, Macdonald, Toyoda, Mako, Jia, Xiaofei, Kuang, Xiaomei T, Mwimanzi, Francis, Mwimanzi, Philip, Walker, Bruce D, Xiong, Yong, Brumme, Zabrina L, Brockman, Mark A, Ueno, Takamasa
Published in mBio (19.01.2016)
Published in mBio (19.01.2016)
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Journal Article
HIV-1 Nef and T-cell activation: a history of contradictions
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Journal Article
Book Review
The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement
Chutiwitoonchai, Nopporn, Hiyoshi, Masateru, Mwimanzi, Philip, Ueno, Takamasa, Adachi, Akio, Ode, Hirotaka, Sato, Hironori, Fackler, Oliver T, Okada, Seiji, Suzu, Shinya
Published in PloS one (15.11.2011)
Published in PloS one (15.11.2011)
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Journal Article
Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?
Mwimanzi, Philip, Markle, Tristan J, Ueno, Takamasa, Brockman, Mark A
Published in Viruses (01.09.2012)
Published in Viruses (01.09.2012)
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Journal Article
Book Review
No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial
Chopera, Denis R, Mann, Jaclyn K, Mwimanzi, Philip, Omarjee, Saleha, Kuang, Xiaomei T, Ndabambi, Nonkululeko, Goodier, Sarah, Martin, Eric, Naranbhai, Vivek, Karim, Salim Abdool, Karim, Quarraisha Abdool, Brumme, Zabrina L, Ndung'u, Thumbi, Williamson, Carolyn, Brockman, Mark A
Published in PloS one (28.08.2013)
Published in PloS one (28.08.2013)
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Journal Article
Brockman, M.A., et al., Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants? Viruses 2012, 4, 1711-1730
Mwimanzi, Philip, Markle, Tristan J, Ueno, Takamasa, Brockman, Mark A
Published in Viruses (05.10.2012)
Published in Viruses (05.10.2012)
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Journal Article
Impairment of viral replication capacity by nef alleles from HIV elite controllers
Mwimanzi, Philip, Markle, Tristan, Otsuka, Hirohito, Ogata, Yoko, Tokunaga, Michiyo, Miura, Toshiyuki, Martin, Eric, Pereyra, Florencia, Walker, Bruce, Brumme, Zabrina, Brockman, Mark, Ueno, Takamasa
Published in Retrovirology (03.10.2011)
Published in Retrovirology (03.10.2011)
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Journal Article
Croton megalobotrys Müll Arg. and Vitex doniana (Sweet): Traditional medicinal plants in a three-step treatment regimen that inhibit in vitro replication of HIV-1
Tietjen, Ian, Gatonye, Teresia, Ngwenya, Barbara N., Namushe, Amos, Simonambanga, Sundana, Muzila, Mbaki, Mwimanzi, Philip, Xiao, Jianbo, Fedida, David, Brumme, Zabrina L., Brockman, Mark A., Andrae-Marobela, Kerstin
Published in Journal of ethnopharmacology (15.09.2016)
Published in Journal of ethnopharmacology (15.09.2016)
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Journal Article
Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A
Tietjen, Ian, Williams, David E., Read, Silven, Kuang, Xiaomei T., Mwimanzi, Philip, Wilhelm, Emmanuelle, Markle, Tristan, Kinloch, Natalie N., Naphen, Cassandra N., Tenney, Karen, Mesplède, Thibault, Wainberg, Mark A., Crews, Phillip, Bell, Brendan, Andersen, Raymond J., Brumme, Zabrina L., Brockman, Mark A.
Published in Antiviral research (01.04.2018)
Published in Antiviral research (01.04.2018)
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Journal Article
Impaired Nef function is associated with early control of HIV-1 viremia
Kuang, Xiaomei T, Li, Xiaoguang, Anmole, Gursev, Mwimanzi, Philip, Shahid, Aniqa, Le, Anh Q, Chong, Louise, Qian, Hua, Miura, Toshiyuki, Markle, Tristan, Baraki, Bemuluyigza, Connick, Elizabeth, Daar, Eric S, Jessen, Heiko, Kelleher, Anthony D, Little, Susan, Markowitz, Martin, Pereyra, Florencia, Rosenberg, Eric S, Walker, Bruce D, Ueno, Takamasa, Brumme, Zabrina L, Brockman, Mark A
Published in Journal of virology (01.09.2014)
Published in Journal of virology (01.09.2014)
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Journal Article
Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: Association with disease progression and influence of immune pressure
Mann, Jaclyn K, Chopera, Denis, Omarjee, Saleha, Kuang, Xiaomei T, Le, Anh Q, Anmole, Gursev, Danroth, Ryan, Mwimanzi, Philip, Reddy, Tarylee, Carlson, Jonathan, Radebe, Mopo, Goulder, Philip J.R, Walker, Bruce D, Abdool Karim, Salim, Novitsky, Vladimir, Williamson, Carolyn, Brockman, Mark A, Brumme, Zabrina L, Ndung’u, Thumbi
Published in Virology (New York, N.Y.) (01.11.2014)
Published in Virology (New York, N.Y.) (01.11.2014)
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Journal Article
Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic
Cotton, Laura A, Kuang, Xiaomei T, Le, Anh Q, Carlson, Jonathan M, Chan, Benjamin, Chopera, Denis R, Brumme, Chanson J, Markle, Tristan J, Martin, Eric, Shahid, Aniqa, Anmole, Gursev, Mwimanzi, Philip, Nassab, Pauline, Penney, Kali A, Rahman, Manal A, Milloy, M-J, Schechter, Martin T, Markowitz, Martin, Carrington, Mary, Walker, Bruce D, Wagner, Theresa, Buchbinder, Susan, Fuchs, Jonathan, Koblin, Beryl, Mayer, Kenneth H, Harrigan, P Richard, Brockman, Mark A, Poon, Art F Y, Brumme, Zabrina L
Published in PLoS genetics (01.04.2014)
Published in PLoS genetics (01.04.2014)
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Journal Article