Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 dose-escalation trial
Longo, Nicola, MD, Harding, Cary O, MD, Burton, Barbara K, MD, Grange, Dorothy K, MD, Vockley, Jerry, MD, Wasserstein, Melissa, MD, Rice, Gregory M, MD, Dorenbaum, Alejandro, MD, Neuenburg, Jutta K, MD, Musson, Donald G, PhD, Gu, Zhonghua, PhD, Sile, Saba, MD
Published in The Lancet (British edition) (05.07.2014)
Published in The Lancet (British edition) (05.07.2014)
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Journal Article
Immunogenicity of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients With Morquio A Syndrome: Results From MOR-004, a Phase III Trial
Schweighardt, Becky, PhD, Tompkins, Troy, BS, Lau, Kelly, MS, Jesaitis, Lynne, PhD, Qi, Yulan, PhD, Musson, Donald G., PhD, Farmer, Pamela, MD, Haller, Christine, MD, Shaywitz, Adam J., MD, PhD, Yang, Ke, PhD, O’Neill, Charles A., PhD
Published in Clinical therapeutics (01.05.2015)
Published in Clinical therapeutics (01.05.2015)
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Nonclinical evaluation of CNS-administered TPP1 enzyme replacement in canine CLN2 neuronal ceroid lipofuscinosis
Vuillemenot, Brian R., Kennedy, Derek, Cooper, Jonathan D., Wong, Andrew M.S., Sri, Sarmi, Doeleman, Thom, Katz, Martin L., Coates, Joan R., Johnson, Gayle C., Reed, Randall P., Adams, Eric L., Butt, Mark T., Musson, Donald G., Henshaw, Joshua, Keve, Steve, Cahayag, Rhea, Tsuruda, Laurie S., O'Neill, Charles A.
Published in Molecular genetics and metabolism (01.02.2015)
Published in Molecular genetics and metabolism (01.02.2015)
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Journal Article
Acetylator Status Impacts Amifampridine Phosphate (Firdapse™) Pharmacokinetics and Exposure to a Greater Extent Than Renal Function
Haroldsen, Peter E., PhD, Sisic, Zlatko, MD, Datt, Joe, MD, Musson, Donald G., PhD, Ingenito, Gary, MD, PhD
Published in Clinical therapeutics (01.07.2017)
Published in Clinical therapeutics (01.07.2017)
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Journal Article
Investigation of high-throughput ultrafiltration for the determination of an unbound compound in human plasma using liquid chromatography and tandem mass spectrometry with electrospray ionization
Zhang, Jin, Musson, Donald G.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (20.10.2006)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (20.10.2006)
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Journal Article
Reversed-phase chiral liquid chromatography on polysaccharide-based stationary phase coupled with tandem mass spectrometry for simultaneous determination of four stereoisomers of MK-0974 in human plasma
Xu, Yang, Musson, Donald G.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.10.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.10.2008)
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Journal Article
Strategies on efficient method development of on-line extraction assays for determination of MK-0974 in human plasma and urine using turbulent-flow chromatography and tandem mass spectrometry
Xu, Yang, Willson, Kenneth J., Musson, Donald G.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2008)
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Application of a novel ultra-low elution volume 96-well solid-phase extraction method to the LC/MS/MS determination of simvastatin and simvastatin acid in human plasma
Yang, Amy Y., Sun, Li, Musson, Donald G., Zhao, Jamie J.
Published in Journal of pharmaceutical and biomedical analysis (01.07.2005)
Published in Journal of pharmaceutical and biomedical analysis (01.07.2005)
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Journal Article
Genetic variation in aryl N‐acetyltransferase results in significant differences in the pharmacokinetic and safety profiles of amifampridine (3,4‐diaminopyridine) phosphate
Haroldsen, Peter E., Garovoy, Marvin R., Musson, Donald G., Zhou, Huiyu, Tsuruda, Laurie, Hanson, Boyd, O'Neill, Charles A.
Published in Pharmacology research & perspectives (01.02.2015)
Published in Pharmacology research & perspectives (01.02.2015)
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Relative bioavailability of sapropterin from intact and dissolved sapropterin dihydrochloride tablets and the effects of food: A randomized, open-label, crossover study in healthy adults
Musson, Donald G., PhD, Kramer, William G., PhD, Foehr, Erik D., PhD, Bieberdorf, Frederick A., MD, Hornfeldt, Carl S., PhD, Kim, Sun Sook, MS, Dorenbaum, Alex, MD
Published in Clinical therapeutics (01.02.2010)
Published in Clinical therapeutics (01.02.2010)
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High turbulence liquid chromatography online extraction and tandem mass spectrometry for the simultaneous determination of suberoylanilide hydroxamic acid and its two metabolites in human serum
Du, Lihong, Musson, Donald G., Wang, Amy Qiu
Published in Rapid communications in mass spectrometry (01.01.2005)
Published in Rapid communications in mass spectrometry (01.01.2005)
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Journal Article
Elimination of diastereomer interference to determine Telcagepant (MK-0974) in human plasma using on-line turbulent-flow technology and off-line solid-phase extraction coupled with liquid chromatography/tandem mass spectrometry
Xu, Yang, Willson, Kenneth J., Anderson, Melanie D.G., Musson, Donald G., Miller-Stein, Cynthia M., Woolf, Eric J.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2009)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2009)
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A new approach for evaluating carryover and its influence on quantitation in high-performance liquid chromatography and tandem mass spectrometry assay
Zeng, Wei, Musson, Donald G., Fisher, Alison L., Wang, Amy Qiu
Published in Rapid communications in mass spectrometry (01.01.2006)
Published in Rapid communications in mass spectrometry (01.01.2006)
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Journal Article
Concerns in the development of an assay for determination of a highly conjugated adsorption-prone compound in human urine
YANG XU, LIHONG DU, ROSE, Mark J, IRONG FU, WOOLF, Eric J, MUSSON, Donald G
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.04.2005)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.04.2005)
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Assay methodology for the quantitation of unbound ertapenem, a new carbapenem antibiotic, in human plasma
Musson, Donald G, Birk, Kimberly L, Kitchen, Chester J, Zhang, Jin, Hsieh, John Y.K, Fang, Wei, Majumdar, Anup K, Rogers, John D
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.01.2003)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.01.2003)
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Journal Article
Pharmacokinetic and Pharmacodynamic Evaluation of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients with Morquio A Syndrome
Qi, Yulan, Musson, Donald G., Schweighardt, Becky, Tompkins, Troy, Jesaitis, Lynne, Shaywitz, Adam J., Yang, Ke, O’Neill, Charles A.
Published in Clinical pharmacokinetics (01.12.2014)
Published in Clinical pharmacokinetics (01.12.2014)
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Journal Article
High-throughput liquid chromatography for drug analysis in biological fluids: investigation of extraction column life
Zeng, Wei, Fisher, Alison L, Musson, Donald G, Wang, Amy Qiu
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.07.2004)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.07.2004)
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Journal Article
Maternal phenylketonuria syndrome: studies in mice suggest a potential approach to a continuing problem
Zeile, William L, McCune, Helen C, Musson, Donald G, O'Donnell, Brian, O'Neill, Charles A, Tsuruda, Laurie S, Zori, Roberto T, Laipis, Philip J
Published in Pediatric research (01.04.2018)
Published in Pediatric research (01.04.2018)
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