Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism
Willsey, A. Jeremy, Sanders, Stephan J., Li, Mingfeng, Dong, Shan, Tebbenkamp, Andrew T., Muhle, Rebecca A., Reilly, Steven K., Lin, Leon, Fertuzinhos, Sofia, Miller, Jeremy A., Murtha, Michael T., Bichsel, Candace, Niu, Wei, Cotney, Justin, Ercan-Sencicek, A. Gulhan, Gockley, Jake, Gupta, Abha R., Han, Wenqi, He, Xin, Hoffman, Ellen J., Klei, Lambertus, Lei, Jing, Liu, Wenzhong, Liu, Li, Lu, Cong, Xu, Xuming, Zhu, Ying, Mane, Shrikant M., Lein, Ed S., Wei, Liping, Noonan, James P., Roeder, Kathryn, Devlin, Bernie, Sestan, Nenad, State, Matthew W.
Published in Cell (21.11.2013)
Published in Cell (21.11.2013)
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A Genome-wide Association Study of Autism Using the Simons Simplex Collection: Does Reducing Phenotypic Heterogeneity in Autism Increase Genetic Homogeneity?
Chaste, Pauline, Klei, Lambertus, Sanders, Stephan J, Hus, Vanessa, Murtha, Michael T, Lowe, Jennifer K, Willsey, A. Jeremy, Moreno-De-Luca, Daniel, Yu, Timothy W, Fombonne, Eric, Geschwind, Daniel, Grice, Dorothy E, Ledbetter, David H, Mane, Shrikant M, Martin, Donna M, Morrow, Eric M, Walsh, Christopher A, Sutcliffe, James S, Lese Martin, Christa, Beaudet, Arthur L, Lord, Catherine, State, Matthew W, Cook, Edwin H, Devlin, Bernie
Published in Biological psychiatry (1969) (01.05.2015)
Published in Biological psychiatry (1969) (01.05.2015)
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Journal Article
Common genetic variants, acting additively, are a major source of risk for autism
Klei, Lambertus, Sanders, Stephan J, Murtha, Michael T, Hus, Vanessa, Lowe, Jennifer K, Willsey, A Jeremy, Moreno-De-Luca, Daniel, Yu, Timothy W, Fombonne, Eric, Geschwind, Daniel, Grice, Dorothy E, Ledbetter, David H, Lord, Catherine, Mane, Shrikant M, Martin, Christa Lese, Martin, Donna M, Morrow, Eric M, Walsh, Christopher A, Melhem, Nadine M, Chaste, Pauline, Sutcliffe, James S, State, Matthew W, Cook, Jr, Edwin H, Roeder, Kathryn, Devlin, Bernie
Published in Molecular autism (15.10.2012)
Published in Molecular autism (15.10.2012)
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Intellectual Disability Is Associated with Increased Runs of Homozygosity in Simplex Autism
Gamsiz, Ece D., Viscidi, Emma W., Frederick, Abbie M., Nagpal, Shailender, Sanders, Stephan J., Murtha, Michael T., Schmidt, Michael, Triche, Elizabeth W., Geschwind, Daniel H., State, Matthew W., Istrail, Sorin, Cook, Edwin H., Devlin, Bernie, Morrow, Eric M.
Published in American journal of human genetics (11.07.2013)
Published in American journal of human genetics (11.07.2013)
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Use of array CGH to detect exonic copy number variants throughout the genome in autism families detects a novel deletion in TMLHE
Celestino-Soper, Patricia B.S., Shaw, Chad A., Sanders, Stephan J., Li, Jian, Murtha, Michael T., Ercan-Sencicek, A. Gulhan, Davis, Lea, Thomson, Susanne, Gambin, Tomasz, Chinault, A. Craig, Ou, Zhishuo, German, Jennifer R., Milosavljevic, Aleksandar, Sutcliffe, James S., Cook, Edwin H., Stankiewicz, Pawel, State, Matthew W., Beaudet, Arthur L.
Published in Human molecular genetics (15.11.2011)
Published in Human molecular genetics (15.11.2011)
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Journal Article
No evidence for association of autism with rare heterozygous point mutations in Contactin-Associated Protein-Like 2 (CNTNAP2), or in Other Contactin-Associated Proteins or Contactins
Murdoch, John D, Gupta, Abha R, Sanders, Stephan J, Walker, Michael F, Keaney, John, Fernandez, Thomas V, Murtha, Michael T, Anyanwu, Samuel, Ober, Gordon T, Raubeson, Melanie J, DiLullo, Nicholas M, Villa, Natalie, Waqar, Zainabdul, Sullivan, Catherine, Gonzalez, Luis, Willsey, A Jeremy, Choe, So-Yeon, Neale, Benjamin M, Daly, Mark J, State, Matthew W
Published in PLoS genetics (01.01.2015)
Published in PLoS genetics (01.01.2015)
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Journal Article
Modest impact on risk for autism spectrum disorder of rare copy number variants at 15q11.2, specifically breakpoints 1 to 2
Chaste, Pauline, Sanders, Stephan J, Mohan, Kommu N, Klei, Lambertus, Song, Youeun, Murtha, Michael T, Hus, Vanessa, Lowe, Jennifer K, Willsey, A Jeremy, Moreno-De-Luca, Daniel, Yu, Timothy W, Fombonne, Eric, Geschwind, Daniel, Grice, Dorothy E, Ledbetter, David H, Lord, Catherine, Mane, Shrikant M, Martin, Donna M, Morrow, Eric M, Walsh, Christopher A, Sutcliffe, James S, State, Matthew W, Martin, Christa Lese, Devlin, Bernie, Beaudet, Arthur L, Cook, Jr, Edwin H, Kim, Soo-Jeong
Published in Autism research (01.06.2014)
Published in Autism research (01.06.2014)
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The contribution of de novo coding mutations to autism spectrum disorder
Iossifov, Ivan, O’Roak, Brian J., Sanders, Stephan J., Ronemus, Michael, Krumm, Niklas, Levy, Dan, Stessman, Holly A., Witherspoon, Kali T., Vives, Laura, Patterson, Karynne E., Smith, Joshua D., Paeper, Bryan, Nickerson, Deborah A., Dea, Jeanselle, Dong, Shan, Gonzalez, Luis E., Mandell, Jeffrey D., Mane, Shrikant M., Murtha, Michael T., Sullivan, Catherine A., Walker, Michael F., Waqar, Zainulabedin, Wei, Liping, Willsey, A. Jeremy, Yamrom, Boris, Lee, Yoon-ha, Grabowska, Ewa, Dalkic, Ertugrul, Wang, Zihua, Marks, Steven, Andrews, Peter, Leotta, Anthony, Kendall, Jude, Hakker, Inessa, Rosenbaum, Julie, Ma, Beicong, Rodgers, Linda, Troge, Jennifer, Narzisi, Giuseppe, Yoon, Seungtai, Schatz, Michael C., Ye, Kenny, McCombie, W. Richard, Shendure, Jay, Eichler, Evan E., State, Matthew W., Wigler, Michael
Published in Nature (London) (13.11.2014)
Published in Nature (London) (13.11.2014)
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Journal Article
De novo mutations revealed by whole-exome sequencing are strongly associated with autism
Sanders, Stephan J., Murtha, Michael T., Gupta, Abha R., Murdoch, John D., Raubeson, Melanie J., Willsey, A. Jeremy, Ercan-Sencicek, A. Gulhan, DiLullo, Nicholas M., Parikshak, Neelroop N., Stein, Jason L., Walker, Michael F., Ober, Gordon T., Teran, Nicole A., Song, Youeun, El-Fishawy, Paul, Murtha, Ryan C., Choi, Murim, Overton, John D., Bjornson, Robert D., Carriero, Nicholas J., Meyer, Kyle A., Bilguvar, Kaya, Mane, Shrikant M., Šestan, Nenad, Lifton, Richard P., Günel, Murat, Roeder, Kathryn, Geschwind, Daniel H., Devlin, Bernie, State, Matthew W.
Published in Nature (London) (10.05.2012)
Published in Nature (London) (10.05.2012)
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Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism
Sanders, Stephan J., Ercan-Sencicek, A. Gulhan, Hus, Vanessa, Luo, Rui, Murtha, Michael T., Moreno-De-Luca, Daniel, Chu, Su H., Moreau, Michael P., Gupta, Abha R., Thomson, Susanne A., Mason, Christopher E., Bilguvar, Kaya, Celestino-Soper, Patricia B.S., Choi, Murim, Crawford, Emily L., Davis, Lea, Davis Wright, Nicole R., Dhodapkar, Rahul M., DiCola, Michael, DiLullo, Nicholas M., Fernandez, Thomas V., Fielding-Singh, Vikram, Fishman, Daniel O., Frahm, Stephanie, Garagaloyan, Rouben, Goh, Gerald S., Kammela, Sindhuja, Klei, Lambertus, Lowe, Jennifer K., Lund, Sabata C., McGrew, Anna D., Meyer, Kyle A., Moffat, William J., Murdoch, John D., O'Roak, Brian J., Ober, Gordon T., Pottenger, Rebecca S., Raubeson, Melanie J., Song, Youeun, Wang, Qi, Yaspan, Brian L., Yu, Timothy W., Yurkiewicz, Ilana R., Beaudet, Arthur L., Cantor, Rita M., Curland, Martin, Grice, Dorothy E., Günel, Murat, Lifton, Richard P., Mane, Shrikant M., Martin, Donna M., Shaw, Chad A., Sheldon, Michael, Tischfield, Jay A., Walsh, Christopher A., Morrow, Eric M., Ledbetter, David H., Fombonne, Eric, Lord, Catherine, Martin, Christa Lese, Brooks, Andrew I., Sutcliffe, James S., Cook, Edwin H., Geschwind, Daniel, Roeder, Kathryn, Devlin, Bernie, State, Matthew W.
Published in Neuron (Cambridge, Mass.) (09.06.2011)
Published in Neuron (Cambridge, Mass.) (09.06.2011)
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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Barrett, Jeffrey C, Hansoul, Sarah, Nicolae, Dan L, Cho, Judy H, Duerr, Richard H, Rioux, John D, Brant, Steven R, Silverberg, Mark S, Taylor, Kent D, Barmada, M Michael, Bitton, Alain, Dassopoulos, Themistocles, Datta, Lisa Wu, Green, Todd, Griffiths, Anne M, Kistner, Emily O, Murtha, Michael T, Regueiro, Miguel D, Rotter, Jerome I, Schumm, L Philip, Steinhart, A Hillary, Targan, Stephan R, Xavier, Ramnik J, Libioulle, Cécile, Sandor, Cynthia, Lathrop, Mark, Belaiche, Jacques, Dewit, Olivier, Gut, Ivo, Heath, Simon, Laukens, Debby, Mni, Myriam, Rutgeerts, Paul, Van Gossum, André, Zelenika, Diana, Franchimont, Denis, Hugot, Jean-Pierre, de Vos, Martine, Vermeire, Severine, Louis, Edouard, Cardon, Lon R, Anderson, Carl A, Drummond, Hazel, Nimmo, Elaine, Ahmad, Tariq, Prescott, Natalie J, Onnie, Clive M, Fisher, Sheila A, Marchini, Jonathan, Ghori, Jilur, Bumpstead, Suzannah, Gwilliam, Rhian, Tremelling, Mark, Deloukas, Panos, Mansfield, John, Jewell, Derek, Satsangi, Jack, Mathew, Christopher G, Parkes, Miles, Georges, Michel, Daly, Mark J
Published in Nature genetics (01.08.2008)
Published in Nature genetics (01.08.2008)
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Adjusting Head Circumference for Covariates in Autism: Clinical Correlates of a Highly Heritable Continuous Trait
Chaste, Pauline, Klei, Lambertus, Sanders, Stephan J, Murtha, Michael T, Hus, Vanessa, Lowe, Jennifer K, Willsey, A. Jeremy, Moreno-De-Luca, Daniel, Yu, Timothy W, Fombonne, Eric, Geschwind, Daniel, Grice, Dorothy E, Ledbetter, David H, Lord, Catherine, Mane, Shrikant M, Lese Martin, Christa, Martin, Donna M, Morrow, Eric M, Walsh, Christopher A, Sutcliffe, James S, State, Matthew W, Devlin, Bernie, Cook, Edwin H, Kim, Soo-Jeong
Published in Biological psychiatry (1969) (15.10.2013)
Published in Biological psychiatry (1969) (15.10.2013)
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Journal Article
Gene expression analysis by transcript profiling coupled to a gene database query
Shimkets, Richard A, Lowe, David G, Tai, Julie Tsu-Ning, Sehl, Patricia, Jin, Hongkui, Yang, Renhui, Predki, Paul F, Rothberg, Bonnie E. G, Murtha, Michael T, Roth, Matthew E, Shenoy, Suresh G, Windemuth, Andreas, Simpson, John W, Simons, Jan F, Daley, Michael P, Gold, Steven A, McKenna, Michael P, Hillan, Kenneth, Went, Gregory T, Rothberg, Jonathan M
Published in Nature biotechnology (01.08.1999)
Published in Nature biotechnology (01.08.1999)
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Expansion of the Hox Gene Family and the Evolution of Chordates
Pendleton, John W., Nagai, Brian K., Murtha, Michael T., Ruddle, Frank H.
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1993)
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Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci
Sanders, Stephan J., He, Xin, Willsey, A. Jeremy, Ercan-Sencicek, A. Gulhan, Samocha, Kaitlin E., Cicek, A. Ercument, Murtha, Michael T., Bal, Vanessa H., Bishop, Somer L., Dong, Shan, Goldberg, Arthur P., Jinlu, Cai, Keaney, John F., Klei, Lambertus, Mandell, Jeffrey D., Moreno-De-Luca, Daniel, Poultney, Christopher S., Robinson, Elise B., Smith, Louw, Solli-Nowlan, Tor, Su, Mack Y., Teran, Nicole A., Walker, Michael F., Werling, Donna M., Beaudet, Arthur L., Cantor, Rita M., Fombonne, Eric, Geschwind, Daniel H., Grice, Dorothy E., Lord, Catherine, Lowe, Jennifer K., Mane, Shrikant M., Martin, Donna M., Morrow, Eric M., Talkowski, Michael E., Sutcliffe, James S., Walsh, Christopher A., Yu, Timothy W., Ledbetter, David H., Martin, Christa Lese, Cook, Edwin H., Buxbaum, Joseph D., Daly, Mark J., Devlin, Bernie, Roeder, Kathryn, State, Matthew W.
Published in Neuron (Cambridge, Mass.) (23.09.2015)
Published in Neuron (Cambridge, Mass.) (23.09.2015)
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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
Weiner, Daniel J, Wigdor, Emilie M, Ripke, Stephan, Walters, Raymond K, Kosmicki, Jack A, Grove, Jakob, Samocha, Kaitlin E, Goldstein, Jacqueline I, Okbay, Aysu, Bybjerg-Grauholm, Jonas, Werge, Thomas, Hougaard, David M, Taylor, Jacob, Skuse, David, Devlin, Bernie, Anney, Richard, Sanders, Stephan J, Bishop, Somer, Mortensen, Preben Bo, Børglum, Anders D, Smith, George Davey, Daly, Mark J, Robinson, Elise B
Published in Nature genetics (01.07.2017)
Published in Nature genetics (01.07.2017)
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
The Psychiatric Genomics Consortium, The Autism Spectrum Disorders Working Group Of, Anney, Richard J L, Ripke, Stephan, Anttila, Verneri, Grove, Jakob, Holmans, Peter, Huang, Hailiang, Klei, Lambertus, Lee, Phil H, Medland, Sarah E, Neale, Benjamin, Robinson, Elise, Weiss, Lauren A, Zwaigenbaum, Lonnie, Yu, Timothy W, Wittemeyer, Kerstin, Willsey, a Jeremy, Wijsman, Ellen M, Werge, Thomas, Wassink, Thomas H, Waltes, Regina, Walsh, Christopher A, Wallace, Simon, Vorstman, Jacob a S, Vieland, Veronica J, Vicente, Astrid M, Vanengeland, Herman, Tsang, Kathryn, Thompson, Ann P, Szatmari, Peter, Svantesson, Oscar, Steinberg, Stacy, Stefansson, Kari, Stefansson, Hreinn, State, Matthew W, Soorya, Latha, Silagadze, Teimuraz, Scherer, Stephen W, Schellenberg, Gerard D, Sandin, Sven, Sanders, Stephan J, Saemundsen, Evald, Rouleau, Guy A, Rogé, Bernadette, Roeder, Kathryn, Roberts, Wendy, Reichert, Jennifer, Reichenberg, Abraham, Rehnström, Karola, Regan, Regina, Poustka, Fritz, Poultney, Christopher S, Piven, Joseph, Pinto, Dalila, Pericak-Vance, Margaret A, Pejovic-Milovancevic, Milica, Pedersen, Marianne Giørtz, Pedersen, Carsten Bøcker, Paterson, Andrew D, Parr, Jeremy R, Pagnamenta, Alistair T, Oliveira, Guiomar, Nurnberger, John I, Nordentoft, Merete, Murtha, Michael T, Mouga, Susana, Mortensen, Preben Bo, Mors, Ole, Morrow, Eric M, Moreno-De-Luca, Daniel, Monaco, Anthony P, Minshew, Nancy, Merikangas, Alison, Mcmahon, William M, Mcgrew, Susan G, Mattheisen, Manuel, Martsenkovsky, Igor, Martin, Donna M, Mane, Shrikant M, Magnusson, Pall, Magalhaes, Tiago, Maestrini, Elena, Lowe, Jennifer K, Lord, Catherine, Levitt, Pat, Martin, Christa Lese, Ledbetter, David H, Leboyer, Marion, Lecouteur, Ann S, Ladd-Acosta, Christine, Kolevzon, Alexander, Klauck, Sabine M, Jacob, Suma, Iliadou, Bozenna, Hultman, Christina M, Hougaard, David M, Hertz-Picciotto, Irva, Hendren, Robert, Hansen, Christine Søholm, Haines, Jonathan L
Published in Molecular autism (22.05.2017)
Published in Molecular autism (22.05.2017)
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Expression Pattern of a Murine Homeobox Gene, Dbx, Displays Extreme Spatial Restriction in Embryonic Forebrain and Spinal Cord
Lu, Sangwei, Bogarad, Leonard D., Murtha, Michael T., Ruddle, Frank H.
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1992)
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1992)
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Journal Article
A genomewide association study of autism using the Simons Simplex Collection: Does reducing phenotypic heterogeneity in autism increase genetic homogeneity?
Chaste, Pauline, Klei, Lambertus, Sanders, Stephan J., Hus, Vanessa, Murtha, Michael T., Lowe, Jennifer K., Willsey, A. Jeremy, Moreno-De-Luca, Daniel, Yu, Timothy W., Fombonne, Eric, Geschwind, Daniel, Grice, Dorothy E., Ledbetter, David H., Mane, Shrikant M., Martin, Donna M., Morrow, Eric M., Walsh, Christopher A., Sutcliffe, James S., Martin, Christa Lese, Beaudet, Arthur L., Lord, Catherine, State, Matthew W., Cook, Edwin H., Devlin, Bernie
Published in Biological psychiatry (1969) (30.09.2014)
Published in Biological psychiatry (1969) (30.09.2014)
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