Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer
Vandekerkhove, Gillian, Lavoie, Jean-Michel, Annala, Matti, Murtha, Andrew J, Sundahl, Nora, Walz, Simon, Sano, Takeshi, Taavitsainen, Sinja, Ritch, Elie, Fazli, Ladan, Hurtado-Coll, Antonio, Wang, Gang, Nykter, Matti, Black, Peter C, Todenhöfer, Tilman, Ost, Piet, Gibb, Ewan A, Chi, Kim N, Eigl, Bernhard J, Wyatt, Alexander W
Published in Nature communications (08.01.2021)
Published in Nature communications (08.01.2021)
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BRCA2 , ATM , and CDK12 Defects Differentially Shape Prostate Tumor Driver Genomics and Clinical Aggression
Warner, Evan, Herberts, Cameron, Fu, Simon, Yip, Steven, Wong, Amanda, Wang, Gang, Ritch, Elie, Murtha, Andrew J, Vandekerkhove, Gillian, Fonseca, Nicolette M, Angeles, Arkhjamil, Beigi, Arshia, Schönlau, Elena, Beja, Kevin, Annala, Matti, Khalaf, Daniel, Chi, Kim N, Wyatt, Alexander W
Published in Clinical cancer research (15.03.2021)
Published in Clinical cancer research (15.03.2021)
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Identification of Hypermutation and Defective Mismatch Repair in ctDNA from Metastatic Prostate Cancer
Ritch, Elie, Fu, Simon Y F, Herberts, Cameron, Wang, Gang, Warner, Evan W, Schönlau, Elena, Taavitsainen, Sinja, Murtha, Andrew J, Vandekerkhove, Gillian, Beja, Kevin, Loktionova, Yulia, Khalaf, Daniel, Fazli, Ladan, Kushnir, Igal, Ferrario, Cristiano, Hotte, Sebastien, Annala, Matti, Chi, Kim N, Wyatt, Alexander W
Published in Clinical cancer research (01.03.2020)
Published in Clinical cancer research (01.03.2020)
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Activating AKT1 and PIK3CA Mutations in Metastatic Castration-Resistant Prostate Cancer
Herberts, Cameron, Murtha, Andrew J., Fu, Simon, Wang, Gang, Schönlau, Elena, Xue, Hui, Lin, Dong, Gleave, Anna, Yip, Steven, Angeles, Arkhjamil, Hotte, Sebastien, Tran, Ben, North, Scott, Taavitsainen, Sinja, Beja, Kevin, Vandekerkhove, Gillian, Ritch, Elie, Warner, Evan, Saad, Fred, Iqbal, Nayyer, Nykter, Matti, Gleave, Martin E., Wang, Yuzhuo, Annala, Matti, Chi, Kim N., Wyatt, Alexander W.
Published in European urology (01.12.2020)
Published in European urology (01.12.2020)
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Multiregion sampling of de novo metastatic prostate cancer reveals complex polyclonality and augments clinical genotyping
Warner, Evan W, Van der Eecken, Kim, Murtha, Andrew J, Kwan, Edmond M, Herberts, Cameron, Sipola, Joonatan, Ng, Sarah W S, Chen, Xinyi E, Fonseca, Nicolette M, Ritch, Elie, Schönlau, Elena, Bernales, Cecily Q, Donnellan, Gráinne, Munzur, Aslı D, Parekh, Karan, Beja, Kevin, Wong, Amanda, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, De Laere, Bram, Annala, Matti, Vandekerkhove, Gillian, Ost, Piet, Wyatt, Alexander W
Published in Nature cancer (01.01.2024)
Published in Nature cancer (01.01.2024)
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Genomic Features of Lung-Recurrent Hormone-Sensitive Prostate Cancer
Fonseca, Nicolette M, Van der Eecken, Kim, Herberts, Cameron, Verbeke, Sofie, Ng, Sarah W S, Lumen, Nicolaas, Ritch, Elie, Murtha, Andrew J, Bernales, Cecily Q, Schönlau, Elena, Moris, Lisa, Van Dorpe, Jo, Annala, Matti, Wyatt, Alexander W, Ost, Piet
Published in JCO precision oncology (01.05.2022)
Published in JCO precision oncology (01.05.2022)
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Towards accurate genomics for newly diagnosed metastatic prostate cancer
Published in Nature cancer
(01.01.2024)
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Impact of androgen deprivation therapy (ADT) on circulating tumor DNA (ctDNA) detection in de novo metastatic castration-sensitive prostate cancer (mCSPC)
Kwan, Edmond Michael, Murtha, Andrew J, Tu, Wilson, Vasquez Rios, Carlos, Bernales, Cecily Q., Arviola, Shannen Keith, Donnellan, Gráinne, Parekh, Karan, Annala, Matti, Maurice-Dror, Corinne, Vandekerkhove, Gillian, Chi, Kim N., Wyatt, Alexander William
Published in Journal of clinical oncology (01.02.2024)
Published in Journal of clinical oncology (01.02.2024)
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Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer
Fonseca, Nicolette M, Maurice-Dror, Corinne, Herberts, Cameron, Tu, Wilson, Fan, William, Murtha, Andrew J, Kollmannsberger, Catarina, Kwan, Edmond M, Parekh, Karan, Schönlau, Elena, Bernales, Cecily Q, Donnellan, Gráinne, Ng, Sarah W S, Sumiyoshi, Takayuki, Vergidis, Joanna, Noonan, Krista, Finch, Daygen L, Zulfiqar, Muhammad, Miller, Stacy, Parimi, Sunil, Lavoie, Jean-Michel, Hardy, Edward, Soleimani, Maryam, Nappi, Lucia, Eigl, Bernhard J, Kollmannsberger, Christian, Taavitsainen, Sinja, Nykter, Matti, Tolmeijer, Sofie H, Boerrigter, Emmy, Mehra, Niven, van Erp, Nielka P, De Laere, Bram, Lindberg, Johan, Grönberg, Henrik, Khalaf, Daniel J, Annala, Matti, Chi, Kim N, Wyatt, Alexander W
Published in Nature communications (28.02.2024)
Published in Nature communications (28.02.2024)
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Abstract A24: Identifying the genomic and clinical features of AKT1/PIK3CA mutant metastatic prostate cancer using circulating tumor DNA
Herberts, Cameron M., Murtha, Andrew J., Fu, Simon, Wang, Gang, Schönlau, Elena, Gleave, Anna, Yip, Steven, Angeles, Arkhjamil, Hotte, Sebastien, Alshangiti, Abdulraheem, Tran, Ben, North, Scott, Taavitsainen, Sinja, Beja, Kevin, Vandekerkhove, Gillian, Ritch, Elie, Saad, Fred, Iqbal, Nayyer, Gleave, Martin E., Annala, Matti, Chi, Kim N., Wyatt, Alexander W.
Published in Clinical cancer research (01.06.2020)
Published in Clinical cancer research (01.06.2020)
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Abstract A004: Clinical test design affects tumor tissue and ctDNA FGFR gene status in metastatic urothelial cancer: a prospective study
Müller, David C., Vandekerkhove, Gillian, Murtha, Andrew J., Bacon, Jack V.W., Vasquez-Rios, Carlos, Stephenson, Maria, Rostin, Kimia, Schönlau, Elena, Wells, Connor, Parimi, Sunil, Noonan, Krista, Basappa, Naveen S., Ko, Jenny J., Finch, Daygen, Alimohamed, Nimira, Bismar, Tarek A., Wang, Gang, Papadakis, Andreas, Nappi, Lucia, Annala, Matti, Bernales, Cecily Q., Spatz, Alan, Chi, Kim N., Wyatt, Alexander W., Eigl, Bernhard J.
Published in Clinical cancer research (17.05.2024)
Published in Clinical cancer research (17.05.2024)
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Abstract A007: Circulating tumor DNA and tissue staining analyses reveal heterogeneous ERBB2 /HER2 status in urothelial cancer
Vandekerkhove, Gillian, Murtha, Andrew J., Müller, David C., Rostin, Kimia, Vasquez-Rios, Carlos, Nikkola, Jussi, Stephenson, Maria, Fung, Emily, Atwal, Jaskirat, Parekh, Karan, Bernales, Cecily Q., Donnellan, Gráinne, Wang, Gang, Todenhöfer, Tilman, Ost, Piet, Black, Peter C., Chi, Kim N., Eigl, Bernhard J., Wyatt, Alexander W.
Published in Clinical cancer research (17.05.2024)
Published in Clinical cancer research (17.05.2024)
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Abstract IA006: Overcoming complex polyclonality for accurate clinical genotyping in metastatic prostate cancer
Wyatt, Alexander W., Murtha, Andrew J., Warner, Evan, Van der Eecken, Kim, Kwan, Edmond M., Herberts, Cameron, Sipola, Joonatan, Ng, Sarah W.S., Chen, Xinyi E., Fonseca, Nicolette M., Ritch, Elie, Schönlau, Elena, Bernales, Cecily Q., Donnellan, Gráinne, Beja, Kevin, Wong, Amanda, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, De Laere, Bram, Annala, Matti, Vandekerkhove, Gillian, Ost, Piet
Published in Cancer research (Chicago, Ill.) (02.06.2023)
Published in Cancer research (Chicago, Ill.) (02.06.2023)
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Abstract 41: Multi-focal genomic dissection of synchronous primary and metastatic tissue from de novo metastatic prostate cancer
Warner, Evan, Van der Eecken, Kim, Murtha, Andrew J., Kwan, Edmond M., Ng, Sarah W., Chen, Xinyi E., Bernales, Cecily Q., Donnellan, Grainne, Schonlau, Elena, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, Vandekerkhove, Gillian, Ritch, Elie, Annala, Matti, De Laere, Bram, Ost, Piet, Wyatt, Alexander W.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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