Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques
MALCOLM, R. Karl, VEAZEY, Ronald S, DOYLE, Lara A, RASMUSSEN, Kelsi K, GOLDMAN, Laurie, KETAS, Thomas J, MOORE, John P, GEER, Leslie, LOWRY, Deborah, FETHERSTON, Susan M, MURPHY, Diarmaid J, BOYD, Peter, MAJOR, Ian, SHATTOCK, Robin J, KLASSE, Per Johan
Published in Antimicrobial Agents and Chemotherapy (01.05.2012)
Published in Antimicrobial Agents and Chemotherapy (01.05.2012)
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Journal Article
Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel
Dallal Bashi, Yahya H., Murphy, Diarmaid J., McCoy, Clare F., Boyd, Peter, Brown, Leeanne, Kihara, Matthew, Martin, François, McMullen, Nicole, Kleinbeck, Kyle, Dangi, Bindi, Spence, Patrick, Hansraj, Bashir, Devlin, Brid, Malcolm, R. Karl
Published in International journal of pharmaceutics: X (01.12.2021)
Published in International journal of pharmaceutics: X (01.12.2021)
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Journal Article
In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel
Murphy, Diarmaid J., Dallal Bashi, Yahya H., McCoy, Clare F., Boyd, Peter, Brown, Leeanne, Martin, François, McMullen, Nicole, Kleinbeck, Kyle, Dangi, Bindi, Spence, Patrick, Hansraj, Bashir, Devlin, Bríd, Malcolm, R. Karl
Published in International journal of pharmaceutics: X (01.12.2022)
Published in International journal of pharmaceutics: X (01.12.2022)
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Journal Article
Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings
McCoy, Clare F., Spence, Patrick, Dallal Bashi, Yahya H., Murphy, Diarmaid J., Boyd, Peter, Dangi, Bindi, Derrick, Tiffany, Devlin, Bríd, Kleinbeck, Kyle, Malcolm, R. Karl
Published in International journal of pharmaceutics: X (01.12.2021)
Published in International journal of pharmaceutics: X (01.12.2021)
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Journal Article
A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department
Jenkins, Mark G., MBChB, Murphy, Diarmaid J., PhD, Little, Carol, RN, McDonald, Julie, RN, McCarron, Paul A., PhD
Published in Annals of emergency medicine (01.06.2014)
Published in Annals of emergency medicine (01.06.2014)
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Journal Article
Microbicide vaginal rings: Technological challenges and clinical development
Malcolm, R. Karl, Boyd, Peter J., McCoy, Clare F., Murphy, Diarmaid J.
Published in Advanced drug delivery reviews (01.08.2016)
Published in Advanced drug delivery reviews (01.08.2016)
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Journal Article
Preliminary Clinical Assessment of Polyvinyl Alcohol–Tetrahydroxyborate Hydrogels as Potential Topical Formulations for Local Anesthesia of Lacerations
McCarron, Paul A., Murphy, Diarmaid J., Little, Claire, McDonald, Julie, Kelly, Oonagh J., Jenkins, Mark G.
Published in Academic emergency medicine (01.04.2011)
Published in Academic emergency medicine (01.04.2011)
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Journal Article
Two into one does go: Formulation development of a multipurpose combination vaginal ring releasing dapivirine and metronidazole for prevention of HIV infection and treatment of bacterial vaginosis
Zhao, Xinyu, Boyd, Peter, Bashi, Yahya Dallal, Murphy, Diarmaid J., McCoy, Clare F., Coulter, Sophie, Laverty, Garry, Malcolm, R. Karl
Published in International journal of pharmaceutics (15.12.2023)
Published in International journal of pharmaceutics (15.12.2023)
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Journal Article
In vitro release testing methods for drug-releasing vaginal rings
Boyd, Peter, Variano, Bruce, Spence, Patrick, McCoy, Clare F., Murphy, Diarmaid J., Dallal Bashi, Yahya H., Malcolm, R. Karl
Published in Journal of controlled release (10.11.2019)
Published in Journal of controlled release (10.11.2019)
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Journal Article
Mechanical testing methods for drug-releasing vaginal rings
McCoy, Clare F., Millar, Bronagh G., Murphy, Diarmaid J., Blanda, Wendy, Hansraj, Bashir, Devlin, Brid, Malcolm, R. Karl, Boyd, Peter
Published in International journal of pharmaceutics (25.03.2019)
Published in International journal of pharmaceutics (25.03.2019)
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Journal Article
Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel
Boyd, Peter, Fetherston, Susan M., McCoy, Clare F., Major, Ian, Murphy, Diarmaid J., Kumar, Sandeep, Holt, Jonathon, Brimer, Andrew, Blanda, Wendy, Devlin, Brid, Malcolm, R. Karl
Published in International journal of pharmaceutics (10.09.2016)
Published in International journal of pharmaceutics (10.09.2016)
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Journal Article
Drug stability and product performance characteristics of a dapivirine-releasing vaginal ring under simulated real-world conditions
Murphy, Diarmaid J., McCoy, Clare F., Boyd, Peter, Derrick, Tiffany, Spence, Patrick, Devlin, Brid, Malcolm, R. Karl
Published in International journal of pharmaceutics (30.06.2019)
Published in International journal of pharmaceutics (30.06.2019)
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Journal Article
Impact of ring size and drug loading on the pharmacokinetics of a combination dapivirine-darunavir vaginal ring in cynomolgus macaques
Murphy, Diarmaid J., Desjardins, Delphine, Boyd, Peter, Dereuddre-Bosquet, Nathalie, Stimmer, Lev, Caldwell, Anna, Le Grand, Roger, Kelly, Charles, van Roey, Jens, Malcolm, R. Karl
Published in International journal of pharmaceutics (25.10.2018)
Published in International journal of pharmaceutics (25.10.2018)
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Journal Article
Towards a dapivirine and levonorgestrel multipurpose vaginal ring: Investigations into the reaction between levonorgestrel and addition-cure silicone elastomers
Dallal Bashi, Yahya H., McCoy, Clare F., Murphy, Diarmaid J., Boyd, Peter, Spence, Patrick, Kleinbeck, Kyle, Devlin, Bríd, Malcolm, R. Karl
Published in International journal of pharmaceutics (05.10.2019)
Published in International journal of pharmaceutics (05.10.2019)
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Journal Article
Packing Polymorphism of Dapivirine and Its Impact on the Performance of a Dapivirine-Releasing Silicone Elastomer Vaginal Ring
McCoy, Clare F., Murphy, Diarmaid J., Boyd, Peter, Derrick, Tiffany, Spence, Patrick, Devlin, Brid, Malcolm, R. Karl
Published in Journal of pharmaceutical sciences (01.08.2017)
Published in Journal of pharmaceutical sciences (01.08.2017)
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Journal Article
Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir
Murphy, Diarmaid J, Desjardins, Delphine, Dereuddre-Bosquet, Nathalie, Brochard, Patricia, Perrot, Ludivine, Pruvost, Alain, Le Grand, Roger, Lagatie, Ole, Vanhooren, Leen, Feyaerts, Maxim, van Roey, Jens, Malcolm, R Karl
Published in Journal of antimicrobial chemotherapy (01.09.2014)
Published in Journal of antimicrobial chemotherapy (01.09.2014)
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Journal Article
Controlling levonorgestrel binding and release in a multi-purpose prevention technology vaginal ring device
Murphy, Diarmaid J., Boyd, Peter, McCoy, Clare F., Kumar, Sandeep, Holt, Jonathon D.S., Blanda, Wendy, Brimer, Andrew N., Malcolm, R. Karl
Published in Journal of controlled release (28.03.2016)
Published in Journal of controlled release (28.03.2016)
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Journal Article
Post-use ring weight and residual drug content as potential objective measures of user adherence to a contraceptive progesterone vaginal ring
Murphy, Diarmaid J., McCoy, Clare F., Plagianos, Marlena, RamaRao, Saumya, Merkatz, Ruth, Clark, Heather, Boyd, Peter, Variano, Bruce, Malcolm, R. Karl
Published in Contraception (Stoneham) (01.09.2019)
Published in Contraception (Stoneham) (01.09.2019)
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Journal Article
Refining the in vitro release test method for a dapivirine-releasing vaginal ring to match in vivo performance
Murphy, Diarmaid J., Lim, Deanna, Armstrong, Ryan, McCoy, Clare F., Bashi, Yahya H. Dallal, Boyd, Peter, Derrick, Tiffany, Spence, Patrick, Devlin, Bríd, Malcolm, R. Karl
Published in Drug delivery and translational research (01.08.2023)
Published in Drug delivery and translational research (01.08.2023)
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Journal Article
Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220
Fetherston, Susan M, Geer, Leslie, Veazey, Ronald S, Goldman, Laurie, Murphy, Diarmaid J, Ketas, Thomas J, Klasse, Per Johan, Blois, Sylvain, La Colla, Paolo, Moore, John P, Malcolm, R Karl
Published in Journal of antimicrobial chemotherapy (01.02.2013)
Published in Journal of antimicrobial chemotherapy (01.02.2013)
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