Targeting the apoptosis pathway to treat tumours of the paediatric nervous system
Fitzgerald, Marie-Claire, O'Halloran, Philip J, Connolly, Niamh M C, Murphy, Brona M
Published in Cell death & disease (14.05.2022)
Published in Cell death & disease (14.05.2022)
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The identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that mediate distinct roles in chemotherapy resistance
Fitzgerald, Marie-Claire, O’Halloran, Philip J., Kerrane, Sean A., Ní Chonghaile, Triona, Connolly, Niamh M. C., Murphy, Brona M.
Published in Cell death & disease (28.10.2023)
Published in Cell death & disease (28.10.2023)
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Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist
Boccellato, Chiara, Kolbe, Emily, Peters, Nathalie, Juric, Viktorija, Fullstone, Gavin, Verreault, Maïté, Idbaih, Ahmed, Lamfers, Martine L. M., Murphy, Brona M., Rehm, Markus
Published in Cell death & disease (01.07.2021)
Published in Cell death & disease (01.07.2021)
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Journal Article
Synthesis and characterisation of a novel mono functionalisable Pt(IV) oxaliplatin-type complex and its peptide conjugate
Kitteringham, Eolann, McKeon, Aoife M., O'Dowd, Paul, Devocelle, Marc, Murphy, Brona M., Griffith, Darren M.
Published in Inorganica Chimica Acta (24.05.2020)
Published in Inorganica Chimica Acta (24.05.2020)
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Journal Article
System-based approaches as prognostic tools for glioblastoma
Salvucci, Manuela, Zakaria, Zaitun, Carberry, Steven, Tivnan, Amanda, Seifert, Volker, Kögel, Donat, Murphy, Brona M, Prehn, Jochen H M
Published in BMC cancer (12.11.2019)
Published in BMC cancer (12.11.2019)
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Journal Article
Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation
Juric, Viktorija, Hudson, Lance, Fay, Joanna, Richards, Cathy E, Jahns, Hanne, Verreault, Maïté, Bielle, Franck, Idbaih, Ahmed, Lamfers, Martine L M, Hopkins, Ann M, Rehm, Markus, Murphy, Brona M
Published in Cell death & disease (03.08.2021)
Published in Cell death & disease (03.08.2021)
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Journal Article
Targeting Autophagy in Glioblastoma
Noonan, Janis, Zarrer, Jennifer, Murphy, Brona M
Published in Critical reviews in oncogenesis (2016)
Published in Critical reviews in oncogenesis (2016)
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Journal Article
Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers
Lindner, Andreas U., Lucantoni, Federico, Varešlija, Damir, Resler, Alexa, Murphy, Brona M., Gallagher, William M., Hill, Arnold D. K., Young, Leonie S., Prehn, Jochen H. M.
Published in Journal of molecular medicine (Berlin, Germany) (01.10.2018)
Published in Journal of molecular medicine (Berlin, Germany) (01.10.2018)
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Journal Article
Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism
Lincoln, Frank A, Imig, Dirke, Boccellato, Chiara, Juric, Viktorija, Noonan, Janis, Kontermann, Roland E, Allgöwer, Frank, Murphy, Brona M, Rehm, Markus
Published in Cell death & disease (01.11.2018)
Published in Cell death & disease (01.11.2018)
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Journal Article
Identification of a Novel Bcl-2-interacting Mediator of Cell Death (Bim) E3 Ligase, Tripartite Motif-containing Protein 2 (TRIM2), and Its Role in Rapid Ischemic Tolerance-induced Neuroprotection
Thompson, Simon, Pearson, Andrea N., Ashley, Michelle D., Jessick, Veronica, Murphy, Brona M., Gafken, Philip, Henshall, David C., Morris, Kate T., Simon, Roger P., Meller, Robert
Published in The Journal of biological chemistry (03.06.2011)
Published in The Journal of biological chemistry (03.06.2011)
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Journal Article
Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM
Juric, Viktorija, Düssmann, Heiko, Lamfers, Martine L M, Prehn, Jochen H M, Rehm, Markus, Murphy, Brona M
Published in Cells (Basel, Switzerland) (12.05.2021)
Published in Cells (Basel, Switzerland) (12.05.2021)
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Journal Article
PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours
Davern, Maria, Fitzgerald, Marie-Claire, Buckley, Croí E., Heeran, Aisling B., Donlon, Noel E., McGrath, Jason, O’ Connell, Fiona, Deshpande, Malvika R., Hayes, Conall, MacDonald, Jamie, Sheppard, Andrew D., Reynolds, John V., Maher, Stephen G., Lynam-Lennon, Niamh, Murphy, Brona, Lysaght, Joanne
Published in Translational oncology (01.05.2022)
Published in Translational oncology (01.05.2022)
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Journal Article
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma
Engel, Tobias, Murphy, Brona M, Hatazaki, Seiji, Jimenez-Mateos, Eva M, Concannon, Caoimhin G, Woods, Ina, Prehn, Jochen H.M, Henshall, David C
Published in The FASEB journal (01.03.2010)
Published in The FASEB journal (01.03.2010)
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Journal Article
Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma
Noonan, Janis J, Jarzabek, Monika, Lincoln, Frank A, Cavanagh, Brenton L, Pariag, Arhona R, Juric, Viktorija, Young, Leonie S, Ligon, Keith L, Jahns, Hanne, Zheleva, Daniella, Prehn, Jochen H M, Rehm, Markus, Byrne, Annette T, Murphy, Brona M
Published in Cancers (12.12.2019)
Published in Cancers (12.12.2019)
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Journal Article
Phenotypic selection through cell death: stochastic modelling of O-6-methylguanine-DNA methyltransferase dynamics
Lasri, Ayoub, Juric, Viktorija, Verreault, Maité, Bielle, Franck, Idbaih, Ahmed, Kel, Alexander, Murphy, Brona, Sturrock, Marc
Published in Royal Society open science (01.07.2020)
Published in Royal Society open science (01.07.2020)
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