Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states
Lake, Eric W., Muretta, Joseph M., Thompson, Andrew R., Rasmussen, Damien M., Majumdar, Abir, Faber, Erik B., Ruff, Emily F., Thomas, David D., Levinson, Nicholas M.
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2018)
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Journal Article
Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V
Trivedi, Darshan V., Muretta, Joseph M., Swenson, Anja M., Davis, Jonathon P., Thomas, David D., Yengo, Christopher M.
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2015)
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Journal Article
The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5
Muretta, Joseph M., Jun, Yonggun, Gross, Steven P., Major, Jennifer, Thomas, David D., Rosenfeld, Steven S.
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.2015)
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Journal Article
A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation
Ruff, Emily F, Muretta, Joseph M, Thompson, Andrew R, Lake, Eric W, Cyphers, Soreen, Albanese, Steven K, Hanson, Sonya M, Behr, Julie M, Thomas, David D, Chodera, John D, Levinson, Nicholas M
Published in eLife (21.02.2018)
Published in eLife (21.02.2018)
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Journal Article
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors
Rasmussen, Damien M, Semonis, Manny M, Greene, Joseph T, Muretta, Joseph M, Thompson, Andrew R, Toledo Ramos, Silvia, Thomas, David D, Pomerantz, William C K, Freedman, Tanya S, Levinson, Nicholas M
Published in eLife (14.05.2024)
Published in eLife (14.05.2024)
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Journal Article
The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry
Atherton, Joseph, Yu, I-Mei, Cook, Alexander, Muretta, Joseph M, Joseph, Agnel, Major, Jennifer, Sourigues, Yannick, Clause, Jeffrey, Topf, Maya, Rosenfeld, Steven S, Houdusse, Anne, Moores, Carolyn A
Published in eLife (11.08.2017)
Published in eLife (11.08.2017)
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Journal Article
Multi-state recognition pathway of the intrinsically disordered protein kinase inhibitor by protein kinase A
Olivieri, Cristina, Wang, Yingjie, Li, Geoffrey C, V S, Manu, Kim, Jonggul, Stultz, Benjamin R, Neibergall, Matthew, Porcelli, Fernando, Muretta, Joseph M, Thomas, David Dt, Gao, Jiali, Blumenthal, Donald K, Taylor, Susan S, Veglia, Gianluigi
Published in eLife (27.04.2020)
Published in eLife (27.04.2020)
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Journal Article
High-throughput FRET assay yields allosteric SERCA activators
Cornea, Razvan L, Gruber, Simon J, Lockamy, Elizabeth L, Muretta, Joseph M, Jin, Dongzhu, Chen, Jiqiu, Dahl, Russell, Bartfai, Tamas, Zsebo, Krisztina M, Gillispie, Gregory D, Thomas, David D
Published in Journal of biomolecular screening (01.01.2013)
Published in Journal of biomolecular screening (01.01.2013)
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Journal Article
Direct detection of the myosin super-relaxed state and interacting-heads motif in solution
Chu, Sami, Muretta, Joseph M., Thomas, David D.
Published in The Journal of biological chemistry (01.10.2021)
Published in The Journal of biological chemistry (01.10.2021)
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Journal Article
Allostery governs Cdk2 activation and differential recognition of CDK inhibitors
Majumdar, Abir, Burban, David J., Muretta, Joseph M., Thompson, Andrew R., Engel, Tiffany A., Rasmussen, Damien M., Subrahmanian, Manu V., Veglia, Gianluigi, Thomas, David D., Levinson, Nicholas M.
Published in Nature chemical biology (01.04.2021)
Published in Nature chemical biology (01.04.2021)
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Journal Article
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin
Ramirez, Maria Paz, Rajaganapathy, Sivaraman, Hagerty, Anthony R., Hua, Cailong, Baxter, Gloria C., Vavra, Joseph, Gordon, Wendy R., Muretta, Joseph M., Salapaka, Murti V., Ervasti, James M.
Published in The Journal of biological chemistry (01.02.2023)
Published in The Journal of biological chemistry (01.02.2023)
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Journal Article
Desmoglein 2 Functions as a Receptor for Fatty Acid Binding Protein 4 in Breast Cancer Epithelial Cells
Chen, Dongmei, Wirth, Keith M, Kizy, Scott, Muretta, Joseph M, Markowski, Todd W, Yong, Peter, Sheka, Adam, Abdelwahab, Hisham, Hertzel, Ann V, Ikramuddin, Sayeed, Yamamoto, Masato, Bernlohr, David A
Published in Molecular cancer research (01.08.2023)
Published in Molecular cancer research (01.08.2023)
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