Efficacy and safety in a 4-year follow-up of the ELEVATE-TN study comparing acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in treatment-naïve chronic lymphocytic leukemia
Sharman, Jeff P., Egyed, Miklos, Jurczak, Wojciech, Skarbnik, Alan, Pagel, John M., Flinn, Ian W., Kamdar, Manali, Munir, Talha, Walewska, Renata, Corbett, Gillian, Fogliatto, Laura Maria, Herishanu, Yair, Banerji, Versha, Coutre, Steven, Follows, George, Walker, Patricia, Karlsson, Karin, Ghia, Paolo, Janssens, Ann, Cymbalista, Florence, Woyach, Jennifer A., Ferrant, Emmanuelle, Wierda, William G., Munugalavadla, Veerendra, Yu, Ting, Wang, Min Hui, Byrd, John C.
Published in Leukemia (01.04.2022)
Published in Leukemia (01.04.2022)
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Journal Article
Acalabrutinib plus Obinutuzumab in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia
Woyach, Jennifer A, Blachly, James S, Rogers, Kerry A, Bhat, Seema A, Jianfar, Mojgan, Lozanski, Gerard, Weiss, David M, Andersen, Barbara L, Gulrajani, Michael, Frigault, Melanie M, Hamdy, Ahmed, Izumi, Raquel, Munugalavadla, Veerendra, Quah, Cheng, Wang, Min-Hui, Byrd, John C
Published in Cancer discovery (01.03.2020)
Published in Cancer discovery (01.03.2020)
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Journal Article
Risk factors for grade 3/4 transaminase elevation in patients with chronic lymphocytic leukemia treated with idelalisib
Brown, Jennifer R., Zelenetz, Andrew, Furman, Richard, Lamanna, Nicole, Mato, Anthony, Montillo, Marco, O’Brien, Susan, Dubowy, Ronald, Gu, Lin, Munugalavadla, Veerendra, Robak, Tadeusz, Hillmen, Peter
Published in Leukemia (01.12.2020)
Published in Leukemia (01.12.2020)
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Journal Article
Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer
Overman, Michael, Javle, Milind, Davis, Richard E, Vats, Pankaj, Kumar-Sinha, Chandan, Xiao, Lianchun, Mettu, Niharika B, Parra, Edwin R, Benson, Al B, Lopez, Charles D, Munugalavadla, Veerendra, Patel, Priti, Tao, Lin, Neelapu, Sattva, Maitra, Anirban
Published in Journal for immunotherapy of cancer (01.02.2020)
Published in Journal for immunotherapy of cancer (01.02.2020)
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Journal Article
The highly selective Bruton tyrosine kinase inhibitor acalabrutinib leaves macrophage phagocytosis intact
Pinney, Jonathan J, Blick-Nitko, Sara K, Baran, Andrea M, Peterson, Derick R, Whitehead, Hannah E, Izumi, Raquel, Munugalavadla, Veerendra, Van DerMeid, Karl R, Barr, Paul M, Zent, Clive S, Elliott, Michael R, Chu, Charles C
Published in Haematologica (Roma) (01.06.2022)
Published in Haematologica (Roma) (01.06.2022)
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Journal Article
Rho Kinase Regulates the Survival and Transformation of Cells Bearing Oncogenic Forms of KIT, FLT3, and BCR-ABL
Mali, Raghuveer Singh, Ramdas, Baskar, Ma, Peilin, Shi, Jianjian, Munugalavadla, Veerendra, Sims, Emily, Wei, Lei, Vemula, Sasidhar, Nabinger, Sarah C., Goodwin, Charles B., Chan, Rebecca J., Traina, Fabiola, Visconte, Valeria, Tiu, Ramon V., Lewis, Timothy A., Stern, Andrew M., Wen, Qiang, Crispino, John D., Boswell, H. Scott, Kapur, Reuben
Published in Cancer cell (13.09.2011)
Published in Cancer cell (13.09.2011)
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Phase I/II results of ceralasertib as monotherapy or in combination with acalabrutinib in high-risk relapsed/refractory chronic lymphocytic leukemia
Jurczak, Wojciech, Elmusharaf, Nagah, Fox, Christopher P., Townsend, William, Paulovich, Amanda G., Whiteaker, Jeffrey R., Krantz, Fanny, Wun, Chuan-Chuan, Parr, Graeme, Sharma, Shringi, Munugalavadla, Veerendra, Manwani, Richa, Dean, Emma, Munir, Talha
Published in Therapeutic advances in hematology (01.01.2023)
Published in Therapeutic advances in hematology (01.01.2023)
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Journal Article
Role of c-Kit and erythropoietin receptor in erythropoiesis
Munugalavadla, Veerendra, Kapur, Reuben
Published in Critical reviews in oncology/hematology (01.04.2005)
Published in Critical reviews in oncology/hematology (01.04.2005)
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Journal Article
Pak and Rac GTPases promote oncogenic KIT-induced neoplasms
Martin, Holly, Mali, Raghuveer Singh, Ma, Peilin, Chatterjee, Anindya, Ramdas, Baskar, Sims, Emily, Munugalavadla, Veerendra, Ghosh, Joydeep, Mattingly, Ray R, Visconte, Valeria, Tiu, Ramon V, Vlaar, Cornelis P, Dharmawardhane, Suranganie, Kapur, Reuben
Published in The Journal of clinical investigation (01.10.2013)
Published in The Journal of clinical investigation (01.10.2013)
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Journal Article
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT
Mali, Raghuveer Singh, Ma, Peilin, Zeng, Li-Fan, Martin, Holly, Ramdas, Baskar, He, Yantao, Sims, Emily, Nabinger, Sarah, Ghosh, Joydeep, Sharma, Namit, Munugalavadla, Veerendra, Chatterjee, Anindya, Li, Shuo, Sandusky, George, Craig, Andrew W., Bunting, Kevin D., Feng, Gen-Sheng, Chan, Rebecca J., Zhang, Zhong-Yin, Kapur, Reuben
Published in Blood (27.09.2012)
Published in Blood (27.09.2012)
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Journal Article
Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor
Chan, Rebecca J., Leedy, Melissa B., Munugalavadla, Veerendra, Voorhorst, Cara S., Li, Yanjun, Yu, Menggang, Kapur, Reuben
Published in Blood (01.05.2005)
Published in Blood (01.05.2005)
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Journal Article
Repression of c-Kit and Its Downstream Substrates by GATA-1 Inhibits Cell Proliferation during Erythroid Maturation
Munugalavadla, Veerendra, Dore, Louis C., Tan, Bai Lin, Hong, Li, Vishnu, Melanie, Weiss, Mitchell J., Kapur, Reuben
Published in Molecular and Cellular Biology (01.08.2005)
Published in Molecular and Cellular Biology (01.08.2005)
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Journal Article
The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor
Ma, Peilin, Mali, Raghuveer Singh, Munugalavadla, Veerendra, Krishnan, Subha, Ramdas, Baskar, Sims, Emily, Martin, Holly, Ghosh, Joydeep, Li, Shuo, Chan, Rebecca J., Krystal, Gerald, Craig, Andrew W., Takemoto, Clifford, Kapur, Reuben
Published in Blood (29.09.2011)
Published in Blood (29.09.2011)
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Journal Article
c-Kit-Mediated Overlapping and Unique Functional and Biochemical Outcomes via Diverse Signaling Pathways
Hong, Li, Munugalavadla, Veerendra, Kapur, Reuben
Published in Molecular and Cellular Biology (01.02.2004)
Published in Molecular and Cellular Biology (01.02.2004)
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Journal Article
The p85α Subunit of Class IA Phosphatidylinositol 3-Kinase Regulates the Expression of Multiple Genes Involved in Osteoclast Maturation and Migration
Munugalavadla, Veerendra, Vemula, Sasidhar, Sims, Emily Catherine, Krishnan, Subha, Chen, Shi, Yan, Jincheng, Li, Huijie, Niziolek, Paul J., Takemoto, Clifford, Robling, Alexander G., Yang, Feng-Chun, Kapur, Reuben
Published in Molecular and Cellular Biology (01.12.2008)
Published in Molecular and Cellular Biology (01.12.2008)
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Journal Article
Balanced Interactions between Lyn, the p85α Regulatory Subunit of Class IA Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation
Ma, Peilin, Vemula, Sasidhar, Munugalavadla, Veerendra, Chen, Jinbiao, Sims, Emily, Borneo, Jovencio, Kondo, Takako, Ramdas, Baskar, Mali, Raghuveer Singh, Li, Shuo, Hashino, Eri, Takemoto, Clifford, Kapur, Reuben
Published in Molecular and Cellular Biology (01.10.2011)
Published in Molecular and Cellular Biology (01.10.2011)
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Journal Article
Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells
Orschell, Christie M, Borneo, Jovencio, Munugalavadla, Veerendra, Ma, Peilin, Sims, Emily, Ramdas, Baskar, Yoder, Mervin C, Kapur, Reuben
Published in Experimental hematology (01.05.2008)
Published in Experimental hematology (01.05.2008)
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Journal Article
Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial
Sharman, Jeff P, Egyed, Miklos, Jurczak, Wojciech, Skarbnik, Alan, Pagel, John M, Flinn, Ian W, Kamdar, Manali, Munir, Talha, Walewska, Renata, Corbett, Gillian, Fogliatto, Laura Maria, Herishanu, Yair, Banerji, Versha, Coutre, Steven, Follows, George, Walker, Patricia, Karlsson, Karin, Ghia, Paolo, Janssens, Ann, Cymbalista, Florence, Woyach, Jennifer A, Salles, Gilles, Wierda, William G, Izumi, Raquel, Munugalavadla, Veerendra, Patel, Priti, Wang, Min Hui, Wong, Sofia, Byrd, John C
Published in The Lancet (British edition) (18.04.2020)
Published in The Lancet (British edition) (18.04.2020)
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Journal Article
Longitudinal Mutation Profiling in CLL Patients during Acalabrutinib Therapy and at Progression
Sun, Clare, Acar, Melih, Jenkins, David, Nuttall, Barrett, White, Rafael, Munugalavadla, Veerendra, Wiestner, Adrian
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article