Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody–Drug Conjugates
Nicolaou, K. C, Erande, Rohan D, Yin, Jun, Vourloumis, Dionisios, Aujay, Monette, Sandoval, Joseph, Munneke, Stefan, Gavrilyuk, Julia
Published in Journal of the American Chemical Society (14.03.2018)
Published in Journal of the American Chemical Society (14.03.2018)
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Streamlined Symmetrical Total Synthesis of Disorazole B-1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues
Nicolaou, K. C., Krieger, Johannes, Murhade, Ganesh M., Subramanian, Parthasarathi, Dherange, Balu D., Vourloumis, Dionisios, Munneke, Stefan, Lin, Baiwei, Gu, Christine, Sarvaiaya, Hetal, Sandoval, Joseph, Zhang, Zhaomei, Aujay, Monette, Purcell, James W., Gavrilyuk, Julia
Published in Journal of the American Chemical Society (09.09.2020)
Published in Journal of the American Chemical Society (09.09.2020)
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Journal Article
Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues
Nicolaou, K. C, Krieger, Johannes, Murhade, Ganesh M, Subramanian, Parthasarathi, Dherange, Balu D, Vourloumis, Dionisios, Munneke, Stefan, Lin, Baiwei, Gu, Christine, Sarvaiaya, Hetal, Sandoval, Joseph, Zhang, Zhaomei, Aujay, Monette, Purcell, James W, Gavrilyuk, Julia
Published in Journal of the American Chemical Society (09.09.2020)
Published in Journal of the American Chemical Society (09.09.2020)
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Applications and Limitations of the I-2-Mediated Carbamate Annulation for the Synthesis of Piperidines: Five- versus Six-Membered Ring Formation
Corkran, Hilary M., Munneke, Stefan, Dangerfield, Emma M., Stocker, Bridget L., Timmer, Mattie S. M.
Published in Journal of organic chemistry (04.10.2013)
Published in Journal of organic chemistry (04.10.2013)
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Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody–Drug Conjugates, Insights into Structure–Activity Relationships, and Tubulysin–Tubulin Binding Derived from X‑ray Crystallographic Analysis
Nicolaou, K. C, Pan, Saiyong, Pulukuri, Kiran K, Ye, Qiuji, Rigol, Stephan, Erande, Rohan D, Vourloumis, Dionisios, Nocek, Bogusław P, Munneke, Stefan, Lyssikatos, Joseph, Valdiosera, Amanda, Gu, Christine, Lin, Baiwei, Sarvaiaya, Hetal, Trinidad, Jose, Sandoval, Joseph, Lee, Christina, Hammond, Mikhail, Aujay, Monette, Taylor, Nicole, Pysz, Marybeth, Purcell, James W, Gavrilyuk, Julia
Published in Journal of organic chemistry (19.02.2021)
Published in Journal of organic chemistry (19.02.2021)
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Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs
Nicolaou, K. C, Rekula, Santhosh Reddy, Kumar, S. Mothish, Podilapu, Ananda Rao, Matuszak, Ryan P, Jung, Paul M, Lam, Lloyd T, Phillips, Andrew C, Lyssikatos, Joseph, Munneke, Stefan, Gu, Christine, Sarvaiya, Hetal, Sandoval, Joseph, Hammond, Mikhail, Aujay, Monette, Purcell, James W, Reilly, Regina M, Gavrilyuk, Julia
Published in Journal of organic chemistry (05.02.2021)
Published in Journal of organic chemistry (05.02.2021)
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Synthesis and Hydrolytic Stability of N‐ and O‐Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of N‐ and O‐Methyloxyamine Linkers for the Synthesis of Glycoconjugates
Munneke, Stefan, Hill, Jaimé C., Timmer, Mattie S. M., Stocker, Bridget L.
Published in European journal of organic chemistry (07.07.2017)
Published in European journal of organic chemistry (07.07.2017)
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Total synthesis of LewisX using a late-stage crystalline intermediate
Munneke, Stefan, Painter, Gavin F., Gainsford, Graeme J., Stocker, Bridget L., Timmer, Mattie S.M.
Published in Carbohydrate research (23.09.2015)
Published in Carbohydrate research (23.09.2015)
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Applications and Limitations of the I2‑Mediated Carbamate Annulation for the Synthesis of Piperidines: Five- versus Six-Membered Ring Formation
Corkran, Hilary M, Munneke, Stefan, Dangerfield, Emma M, Stocker, Bridget L, Timmer, Mattie S. M
Published in Journal of organic chemistry (04.10.2013)
Published in Journal of organic chemistry (04.10.2013)
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Journal Article
Total synthesis of Lewis(X) using a late-stage crystalline intermediate
Munneke, Stefan, Painter, Gavin F., Gainsford, Graeme J., Stocker, Bridget L., Timmer, Mattie S. M.
Published in Carbohydrate research (23.09.2015)
Published in Carbohydrate research (23.09.2015)
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The modular synthesis of multivalent functionalised glycodendrons for the detection of lectins including DC-SIGNElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ra08872h
Munneke, Stefan, Kodar, Kristel, Painter, Gavin F, Stocker, Bridget L, Timmer, Mattie S. M
Year of Publication 22.09.2017
Year of Publication 22.09.2017
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A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates
Gold, Henrik, Munneke, Stefan, Dinkelaar, Jasper, Overkleeft, Herman S., Aerts, Johannes M.F.G., Codée, Jeroen D.C., van der Marel, Gijs A.
Published in Carbohydrate research (06.09.2011)
Published in Carbohydrate research (06.09.2011)
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ChemInform Abstract: Applications and Limitations of the I 2 ‐Mediated Carbamate Annulation for the Synthesis of Piperidines: Five‐ versus Six‐Membered Ring Formation
Corkran, Hilary M., Munneke, Stefan, Dangerfield, Emma M., Stocker, Bridget L., Timmer, Mattie S. M.
Published in ChemInform (11.03.2014)
Published in ChemInform (11.03.2014)
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Journal Article
ChemInform Abstract: Applications and Limitations of the I2-Mediated Carbamate Annulation for the Synthesis of Piperidines: Five- versus Six-Membered Ring Formation
Corkran, Hilary M., Munneke, Stefan, Dangerfield, Emma M., Stocker, Bridget L., Timmer, Mattie S. M.
Published in ChemInform (11.03.2014)
Published in ChemInform (11.03.2014)
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