NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension
Mulvaney, Eamon P, Reid, Helen M, Bialesova, Lucia, Bouchard, Annie, Salvail, Dany, Kinsella, B Therese
Published in BMC pulmonary medicine (06.04.2020)
Published in BMC pulmonary medicine (06.04.2020)
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Journal Article
Evaluation of NTP42 , a novel thromboxane receptor antagonist, in a first-in-human phase I clinical trial
Reid, Helen M, Maginn, Mark, Perkins, C Michael, Mulvaney, Eamon P, Boyce, Malcolm, Yamamoto, Takahiro, Kinsella, B Therese
Published in Frontiers in pharmacology (21.12.2023)
Published in Frontiers in pharmacology (21.12.2023)
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Journal Article
The thromboxane receptor antagonist NTP42 promotes beneficial adaptation and preserves cardiac function in experimental models of right heart overload
Mulvaney, Eamon P, Renzo, Fabiana, Adão, Rui, Dupre, Emilie, Bialesova, Lucia, Salvatore, Viviana, Reid, Helen M, Conceição, Glória, Grynblat, Julien, Llucià-Valldeperas, Aida, Michel, Jean-Baptiste, Brás-Silva, Carmen, Laurent, Charles E, Howard, Luke S, Montani, David, Humbert, Marc, Vonk Noordegraaf, Anton, Perros, Frédéric, Mendes-Ferreira, Pedro, Kinsella, B Therese
Published in Frontiers in cardiovascular medicine (14.12.2022)
Published in Frontiers in cardiovascular medicine (14.12.2022)
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Journal Article
Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension
Mulvaney, Eamon P., Reid, Helen M., Bialesova, Lucia, Mendes-Ferreira, Pedro, Adão, Rui, Brás-Silva, Carmen, Kinsella, B. Therese
Published in European journal of pharmacology (15.12.2020)
Published in European journal of pharmacology (15.12.2020)
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Journal Article
Regulation of protein kinase C-related kinase (PRK) signalling by the TPα and TPβ isoforms of the human thromboxane A 2 receptor: Implications for thromboxane- and androgen- dependent neoplastic and epigenetic responses in prostate cancer
O'Sullivan, Aine G, Mulvaney, Eamon P, Kinsella, B Therese
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2017)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2017)
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Journal Article
Interaction of the human prostacyclin receptor with Rab11. Characterization of a novel Rab11 binding domain within α-helix 8 that is regulated by palmitoylation
Reid, Helen M, Mulvaney, Eamon P, Turner, Elizebeth C, Kinsella, B Therese
Published in The Journal of biological chemistry (03.08.2018)
Published in The Journal of biological chemistry (03.08.2018)
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Journal Article
Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertension
Adão, Rui, Mendes-Ferreira, Pedro, Santos-Ribeiro, Diana, Maia-Rocha, Carolina, Pimentel, Luís D, Monteiro-Pinto, Cláudia, Mulvaney, Eamon P, Reid, Helen M, Kinsella, B Therese, Potus, François, Breuils-Bonnet, Sandra, Rademaker, Miriam T, Provencher, Steeve, Bonnet, Sébastien, Leite-Moreira, Adelino F, Brás-Silva, Carmen
Published in Cardiovascular research (01.07.2018)
Published in Cardiovascular research (01.07.2018)
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Journal Article
Regulated expression of the TPβ isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3.1: Implications for the role of thromboxane in prostate cancer
O'Sullivan, Aine G., Eivers, Sarah B., Mulvaney, Eamon P., Kinsella, B. Therese
Published in Biochimica et biophysica acta. Molecular basis of disease (01.12.2017)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.12.2017)
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Journal Article
Identification of α-helix 4 (α4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor
Mulvaney, Eamon P., O'Meara, Fergal, Khan, Amir R., O'Connell, David J., Kinsella, B. Therese
Published in Biochimica et biophysica acta. Molecular cell research (01.10.2017)
Published in Biochimica et biophysica acta. Molecular cell research (01.10.2017)
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Journal Article
Identification of an interaction between the TPα and TPβ isoforms of the human thromboxane A2 receptor with protein kinase C-related kinase (PRK) 1. Implications for prostate cancer
Turner, Elizebeth C, Kavanagh, David J, Mulvaney, Eamon P, McLean, Caitriona, Wikström, Katarina, Reid, Helen M, Kinsella, B Therese
Published in The Journal of biological chemistry (03.08.2018)
Published in The Journal of biological chemistry (03.08.2018)
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Journal Article
Regulation of protein kinase C-related kinase (PRK) signalling by the TPα and TPβ isoforms of the human thromboxane A2 receptor: Implications for thromboxane- and androgen- dependent neoplastic and epigenetic responses in prostate cancer
O'Sullivan, Aine G., Mulvaney, Eamon P., Kinsella, B. Therese
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2017)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2017)
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Journal Article
Differential expression of the TPα and TPβ isoforms of the human T Prostanoid receptor during chronic inflammation of the prostate: Role for FOXP1 in the transcriptional regulation of TPβ during monocyte-macrophage differentiation
Mulvaney, Eamon P., O'Sullivan, Áine G., Eivers, Sarah B., Reid, Helen M., Kinsella, B. Therese
Published in Experimental and molecular pathology (01.10.2019)
Published in Experimental and molecular pathology (01.10.2019)
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Journal Article
Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential
Mulvaney, Eamon P, Shilling, Christine, Eivers, Sarah B, Perry, Antoinette S, Bjartell, Anders, Kay, Elaine W, Watson, R William, Kinsella, B Therese
Published in Oncotarget (08.11.2016)
Published in Oncotarget (08.11.2016)
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Journal Article
Interaction of the Human Prostacyclin Receptor with Rab11: CHARACTERIZATION OF A NOVEL Rab11 BINDING DOMAIN WITHIN α-HELIX 8 THAT IS REGULATED BY PALMITOYLATION
Reid, Helen M., Mulvaney, Eamon P., Turner, Elizebeth C., Kinsella, B. Therese
Published in The Journal of biological chemistry (11.06.2010)
Published in The Journal of biological chemistry (11.06.2010)
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Journal Article
Transcriptional regulation of the human thromboxane A2 receptor gene by Wilms' tumor (WT)1 and hypermethylated in cancer (HIC) 1 in prostate and breast cancers
Keating, Garret L., Reid, Helen M., Eivers, Sarah B., Mulvaney, Eamon P., Kinsella, B. Therese
Published in Biochimica et biophysica acta (01.06.2014)
Published in Biochimica et biophysica acta (01.06.2014)
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Journal Article
Interaction of the human prostacyclin receptor and the NHERF4 family member intestinal and kidney enriched PDZ protein (IKEPP)
Reid, Helen M., Turner, Elizebeth C., Mulvaney, Eamon P., Hyland, Paula B., McLean, Caitriona, Kinsella, B. Therese
Published in Biochimica et biophysica acta (01.10.2012)
Published in Biochimica et biophysica acta (01.10.2012)
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