Mouse and human urothelial cancer organoids: A tool for bladder cancer research
Mullenders, Jasper, de Jongh, Evelien, Brousali, Anneta, Roosen, Mieke, Blom, Jan P. A., Begthel, Harry, Korving, Jeroen, Jonges, Trudy, Kranenburg, Onno, Meijer, Richard, Clevers, Hans C.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
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Journal Article
Patient-derived organoids as a predictive biomarker for treatment response in cancer patients
Wensink, G. Emerens, Elias, Sjoerd G., Mullenders, Jasper, Koopman, Miriam, Boj, Sylvia F., Kranenburg, Onno W., Roodhart, Jeanine M. L.
Published in NPJ precision oncology (12.04.2021)
Published in NPJ precision oncology (12.04.2021)
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Journal Article
CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank
Geurts, Maarten H., de Poel, Eyleen, Amatngalim, Gimano D., Oka, Rurika, Meijers, Fleur M., Kruisselbrink, Evelien, van Mourik, Peter, Berkers, Gitte, de Winter-de Groot, Karin M., Michel, Sabine, Muilwijk, Danya, Aalbers, Bente L., Mullenders, Jasper, Boj, Sylvia F., Suen, Sylvia W.F., Brunsveld, Jesse E., Janssens, Hettie M., Mall, Marcus A., Graeber, Simon Y., van Boxtel, Ruben, van der Ent, Cornelis K., Beekman, Jeffrey M., Clevers, Hans
Published in Cell stem cell (02.04.2020)
Published in Cell stem cell (02.04.2020)
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Journal Article
TET1 is a tumor suppressor of hematopoietic malignancy
Cimmino, Luisa, Dawlaty, Meelad M, Ndiaye-Lobry, Delphine, Yap, Yoon Sing, Bakogianni, Sofia, Yu, Yiting, Bhattacharyya, Sanchari, Shaknovich, Rita, Geng, Huimin, Lobry, Camille, Mullenders, Jasper, King, Bryan, Trimarchi, Thomas, Aranda-Orgilles, Beatriz, Liu, Cynthia, Shen, Steven, Verma, Amit K, Jaenisch, Rudolf, Aifantis, Iannis
Published in Nature immunology (01.06.2015)
Published in Nature immunology (01.06.2015)
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Journal Article
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
Mullenders, Jasper, Aranda-Orgilles, Beatriz, Lhoumaud, Priscillia, Keller, Matthew, Pae, Juhee, Wang, Kun, Kayembe, Clarisse, Rocha, Pedro P, Raviram, Ramya, Gong, Yixiao, Premsrirut, Prem K, Tsirigos, Aristotelis, Bonneau, Richard, Skok, Jane A, Cimmino, Luisa, Hoehn, Daniela, Aifantis, Iannis
Published in The Journal of experimental medicine (19.10.2015)
Published in The Journal of experimental medicine (19.10.2015)
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Journal Article
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis
Aranda-Orgilles, Beatriz, Saldaña-Meyer, Ricardo, Wang, Eric, Trompouki, Eirini, Fassl, Anne, Lau, Stephanie, Mullenders, Jasper, Rocha, Pedro P., Raviram, Ramya, Guillamot, María, Sánchez-Díaz, María, Wang, Kun, Kayembe, Clarisse, Zhang, Nan, Amoasii, Leonela, Choudhuri, Avik, Skok, Jane A., Schober, Markus, Reinberg, Danny, Sicinski, Piotr, Schrewe, Heinrich, Tsirigos, Aristotelis, Zon, Leonard I., Aifantis, Iannis
Published in Cell stem cell (01.12.2016)
Published in Cell stem cell (01.12.2016)
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Journal Article
Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids
Vonk, Annelotte M., van Mourik, Peter, Ramalho, Anabela S., Silva, Iris A.L., Statia, Marvin, Kruisselbrink, Evelien, Suen, Sylvia W.F., Dekkers, Johanna F., Vleggaar, Frank P., Houwen, Roderick H.J., Mullenders, Jasper, Boj, Sylvia F., Vries, Robert, Amaral, Margarida D., de Boeck, Kris, van der Ent, Cornelis K., Beekman, Jeffrey M.
Published in STAR protocols (19.06.2020)
Published in STAR protocols (19.06.2020)
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Journal Article
Mechanisms of Epigenetic Regulation of Leukemia Onset and Progression
Ntziachristos, Panagiotis, Mullenders, Jasper, Trimarchi, Thomas, Aifantis, Iannis
Published in Advances in Immunology (2013)
Published in Advances in Immunology (2013)
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Book Chapter
Journal Article
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
Beijersbergen, Roderick L, Bernards, René, Berns, Katrien, Hijmans, E. Marielle, Mullenders, Jasper, Brummelkamp, Thijn R, Velds, Arno, Heimerikx, Mike, Kerkhoven, Ron M, Madiredjo, Mandy, Nijkamp, Wouter, Weigelt, Britta, Agami, Reuven, Ge, Wei, Cavet, Guy, Linsley, Peter S
Published in Nature (25.03.2004)
Published in Nature (25.03.2004)
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Journal Article
A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway
Mullenders, Jasper, Fabius, Armida W M, Madiredjo, Mandy, Bernards, René, Beijersbergen, Roderick L
Published in PloS one (11.03.2009)
Published in PloS one (11.03.2009)
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Journal Article
Involvement of MINK, a Ste20 Family Kinase, in Ras Oncogene-Induced Growth Arrest in Human Ovarian Surface Epithelial Cells
Nicke, Barbara, Bastien, Julie, Khanna, Sophia J., Warne, Patricia H., Cowling, Victoria, Cook, Simon J., Peters, Gordon, Delpuech, Oona, Schulze, Almut, Berns, Katrien, Mullenders, Jasper, Beijersbergen, Roderick L., Bernards, René, Ganesan, Trivadi S., Downward, Julian, Hancock, David C.
Published in Molecular cell (09.12.2005)
Published in Molecular cell (09.12.2005)
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Journal Article
Candidate Biomarkers of Response to an Experimental Cancer Drug Identified through a Large-scale RNA Interference Genetic Screen
MULLENDERS, Jasper, VON DER SAAL, Wolfgang, VAN DONGEN, Miranda M. W, REIFF, Ulrike, VAN WILLIGEN, Rogier, BEIJERSBERGEN, Roderick L, TIEFENTHALER, Georg, KLEIN, Christian, BERNARDS, René
Published in Clinical cancer research (15.09.2009)
Published in Clinical cancer research (15.09.2009)
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Journal Article
The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
King, Bryan, Trimarchi, Thomas, Reavie, Linsey, Xu, Luyao, Mullenders, Jasper, Ntziachristos, Panagiotis, Aranda-Orgilles, Beatriz, Perez-Garcia, Arianne, Shi, Junwei, Vakoc, Christopher, Sandy, Peter, Shen, Steven S., Ferrando, Adolfo, Aifantis, Iannis
Published in Cell (20.06.2013)
Published in Cell (20.06.2013)
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Journal Article
Targeting G542X CFTR nonsense alleles with ELX-02 restores CFTR function in human-derived intestinal organoids
Crawford, Daniel K., Mullenders, Jasper, Pott, Johanna, Boj, Sylvia F., Landskroner-Eiger, Shira, Goddeeris, Matthew M.
Published in Journal of cystic fibrosis (01.05.2021)
Published in Journal of cystic fibrosis (01.05.2021)
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Journal Article
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
Ntziachristos, Panagiotis, Tsirigos, Aristotelis, Welstead, G. Grant, Trimarchi, Thomas, Bakogianni, Sofia, Xu, Luyao, Loizou, Evangelia, Holmfeldt, Linda, Strikoudis, Alexandros, King, Bryan, Mullenders, Jasper, Becksfort, Jared, Nedjic, Jelena, Paietta, Elisabeth, Tallman, Martin S., Rowe, Jacob M., Tonon, Giovanni, Satoh, Takashi, Kruidenier, Laurens, Prinjha, Rab, Akira, Shizuo, Van Vlierberghe, Pieter, Ferrando, Adolfo A., Jaenisch, Rudolf, Mullighan, Charles G., Aifantis, Iannis
Published in Nature (London) (23.10.2014)
Published in Nature (London) (23.10.2014)
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Journal Article
Abstract 126: HUB Organoids: bringing the 'patient in the lab' for preclinical and clinical development
Mullenders, Jasper, Buijs, Annemarie, Fielmich, Lars-Eric, Sluimer, Jasper, Sun, Jane, Vries, Robert G., Boj, Sylvia F.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 2977: Organoid-T-cell co-cultures for preclinical testing of adoptive cell and cancer immunotherapy
Hombrink, Pleun, Mardpour, Soura, Spaan, Ewout, Hanrath, Jarmil, Pourfarzad, Farzin, Mullenders, Jasper, Overmeer, Rene, Robert, G.J, Vries, Sylvia, F, Boj
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia
Kourtis, Nikos, Lazaris, Charalampos, Hockemeyer, Kathryn, Balandrán, Juan Carlos, Jimenez, Alejandra R., Mullenders, Jasper, Gong, Yixiao, Trimarchi, Thomas, Bhatt, Kamala, Hu, Hai, Shrestha, Liza, Ambesi-Impiombato, Alberto, Kelliher, Michelle, Paietta, Elisabeth, Chiosis, Gabriela, Guzman, Monica L., Ferrando, Adolfo A., Tsirigos, Aristotelis, Aifantis, Iannis
Published in Nature medicine (01.08.2018)
Published in Nature medicine (01.08.2018)
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Journal Article
Abstract LB-008: Patient derived organoids: Bringing the "patient in the lab" for pre-clinical and clinical development
Mullenders, Jasper, Buijs, Annemarie, Van Maanen, Inge, Piani, Carol, Mardpour, Soura, Clevers, Hans, Vries, Rob, Boj, Sylvia
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Urine-derived bladder cancer organoids (urinoids) as a tool for cancer longitudinal response monitoring and therapy adaptation
Viergever, Bastiaan J., Raats, Daniëlle A. E., Geurts, Veerle, Mullenders, Jasper, Jonges, Trudy N., van der Heijden, Michiel S., van Es, Johan H., Kranenburg, Onno, Meijer, Richard P.
Published in British journal of cancer (24.02.2024)
Published in British journal of cancer (24.02.2024)
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Journal Article