Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1
Krabill, Aaron D, Chen, Hao, Hussain, Sajjad, Hewitt, Chad S, Imhoff, Ryan D, Muli, Christine S, Das, Chittaranjan, Galardy, Paul J, Wendt, Michael K, Flaherty, Daniel P
Published in Molecules (Basel, Switzerland) (25.02.2021)
Published in Molecules (Basel, Switzerland) (25.02.2021)
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Journal Article
Small‐Molecule Inhibitors of the Proteasome's Regulatory Particle
Muli, Christine S., Tian, Wenzhi, Trader, Darci J.
Published in Chembiochem : a European journal of chemical biology (15.07.2019)
Published in Chembiochem : a European journal of chemical biology (15.07.2019)
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Journal Article
Discovery and Development of Cyclic Peptide Proteasome Stimulators
Nelson, Samantha, Harris, Timothy J., Muli, Christine S., Maresh, Marianne E., Baker, Braden, Smith, Chloe, Neumann, Chris, Trader, Darci J., Parkinson, Elizabeth I.
Published in Chembiochem : a European journal of chemical biology (01.02.2024)
Published in Chembiochem : a European journal of chemical biology (01.02.2024)
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Journal Article
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C‑terminal Hydrolase L1
Imhoff, Ryan D., Patel, Rishi, Safdar, Muhammad Hassan, Jones, Hannah B. L., Pinto-Fernandez, Adan, Vendrell, Iolanda, Chen, Hao, Muli, Christine S., Krabill, Aaron D., Kessler, Benedikt M., Wendt, Michael K., Das, Chittaranjan, Flaherty, Daniel P.
Published in Journal of medicinal chemistry (28.03.2024)
Published in Journal of medicinal chemistry (28.03.2024)
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Journal Article
Analysis of chain length, substitution patterns, and unsaturation of AM-404 derivatives as 20S proteasome stimulators
Coleman, Rachel A., Muli, Christine S., Zhao, Yizhou, Bhardwaj, Atul, Newhouse, Timothy R., Trader, Darci J.
Published in Bioorganic & medicinal chemistry letters (01.02.2019)
Published in Bioorganic & medicinal chemistry letters (01.02.2019)
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Journal Article
Discovery of a non-covalent ligand for Rpn-13, a therapeutic target for hematological cancers
Loy, Cody A., Muli, Christine S., Ali, Eslam M.H., Xie, Dan, Ahmed, Mostafa H., Beth Post, Carol, Trader, Darci J.
Published in Bioorganic & medicinal chemistry letters (15.10.2023)
Published in Bioorganic & medicinal chemistry letters (15.10.2023)
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Journal Article
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5‑Fluoro-4-(3H)‑quinazolinone Aryl Urea pan-RAF Kinase Inhibitor
Huestis, Malcolm P, Dela Cruz, Darlene, DiPasquale, Antonio G, Durk, Matthew R, Eigenbrot, Charles, Gibbons, Paul, Gobbi, Alberto, Hunsaker, Thomas L, La, Hank, Leung, Dennis H, Liu, Wendy, Malek, Shiva, Merchant, Mark, Moffat, John G, Muli, Christine S, Orr, Christine J, Parr, Brendan T, Shanahan, Frances, Sneeringer, Christopher J, Wang, Weiru, Yen, Ivana, Yin, Jianping, Siu, Michael, Rudolph, Joachim
Published in Journal of medicinal chemistry (08.04.2021)
Published in Journal of medicinal chemistry (08.04.2021)
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Journal Article
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor
Huestis, Malcolm P, Durk, Matthew R, Eigenbrot, Charles, Gibbons, Paul, Hunsaker, Thomas L, La, Hank, Leung, Dennis H, Liu, Wendy, Malek, Shiva, Merchant, Mark, Moffat, John G, Muli, Christine S, Orr, Christine J, Parr, Brendan T, Shanahan, Frances, Sneeringer, Christopher J, Wang, Weiru, Yen, Ivana, Yin, Jianping, Rudolph, Joachim, Siu, Michael
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Journal Article
Synthesis of sugar oxime ether surfactants
Ewan, Harrison S., Muli, Christine S., Touba, Steven, Bellinghiere, Amy T., Veitschegger, Anne M., Smith, Travis B., Pistel, William L., Jewell, William T., Rowe, Rebecca K., Hagen, John P., Palandoken, Hasan
Published in Tetrahedron letters (27.08.2014)
Published in Tetrahedron letters (27.08.2014)
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Journal Article
Small Molecular Inhibitors of the Proteasome’s Regulatory Particle
Muli, Christine S., Tian, Wenzhi, Trader, Darci J.
Published in Chembiochem : a European journal of chemical biology (24.05.2019)
Published in Chembiochem : a European journal of chemical biology (24.05.2019)
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Journal Article
Abstract 1973: Discovery of the first-in-class SHP1 covalent inhibitor for cancer immunotherapy
Qu, Zihan, Meke, Frederick Nguele, Zhang, Zheng, Bai, Yunpeng, Krabill, Aaron D., Muli, Christine S., Jassim, Brenson A., Dong, Jiajun, Li, Jinyue, Yuyen, Nguyen, Tao, Andy W., Trader, Darci T., Zhang, Zhong-Yin
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
The Physico-Chemical Properties of Sugar-Oxime-Ether Surfactants
Rowe, Rebecca K., Matasci, Katherine R., Rickelmann, Abbey R., Muli, Christine S., Doherty, Erin E., Smith, Travis B., Pistel, William L., McIntyre, Sean, Palandoken, Hasan, Hagen, John P.
Published in Tenside Surfactants Detergents (21.01.2020)
Published in Tenside Surfactants Detergents (21.01.2020)
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Journal Article