Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin
Foster, Benjamin M., Stolz, Paul, Mulholland, Christopher B., Montoya, Alex, Kramer, Holger, Bultmann, Sebastian, Bartke, Till
Published in Molecular cell (15.11.2018)
Published in Molecular cell (15.11.2018)
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Journal Article
Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger
Hata, Keiichi, Kobayashi, Naohiro, Sugimura, Keita, Qin, Weihua, Haxholli, Deis, Chiba, Yoshie, Yoshimi, Sae, Hayashi, Gosuke, Onoda, Hiroki, Ikegami, Takahisa, Mulholland, Christopher B, Nishiyama, Atsuya, Nakanishi, Makoto, Leonhardt, Heinrich, Konuma, Tsuyoshi, Arita, Kyohei
Published in Nucleic acids research (28.11.2022)
Published in Nucleic acids research (28.11.2022)
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Journal Article
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation
Nishiyama, Atsuya, Mulholland, Christopher B., Bultmann, Sebastian, Kori, Satomi, Endo, Akinori, Saeki, Yasushi, Qin, Weihua, Trummer, Carina, Chiba, Yoshie, Yokoyama, Haruka, Kumamoto, Soichiro, Kawakami, Toru, Hojo, Hironobu, Nagae, Genta, Aburatani, Hiroyuki, Tanaka, Keiji, Arita, Kyohei, Leonhardt, Heinrich, Nakanishi, Makoto
Published in Nature communications (06.03.2020)
Published in Nature communications (06.03.2020)
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Journal Article
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex
Gasparoni, Gilles, Bultmann, Sebastian, Lutsik, Pavlo, Kraus, Theo F J, Sordon, Sabrina, Vlcek, Julia, Dietinger, Vanessa, Steinmaurer, Martina, Haider, Melanie, Mulholland, Christopher B, Arzberger, Thomas, Roeber, Sigrun, Riemenschneider, Matthias, Kretzschmar, Hans A, Giese, Armin, Leonhardt, Heinrich, Walter, Jörn
Published in Epigenetics & chromatin (25.07.2018)
Published in Epigenetics & chromatin (25.07.2018)
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Journal Article
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
Mulholland, Christopher B., Nishiyama, Atsuya, Ryan, Joel, Nakamura, Ryohei, Yiğit, Merve, Glück, Ivo M., Trummer, Carina, Qin, Weihua, Bartoschek, Michael D., Traube, Franziska R., Parsa, Edris, Ugur, Enes, Modic, Miha, Acharya, Aishwarya, Stolz, Paul, Ziegenhain, Christoph, Wierer, Michael, Enard, Wolfgang, Carell, Thomas, Lamb, Don C., Takeda, Hiroyuki, Nakanishi, Makoto, Bultmann, Sebastian, Leonhardt, Heinrich
Published in Nature communications (24.11.2020)
Published in Nature communications (24.11.2020)
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Journal Article
Ubiquitome Analysis Reveals PCNA-Associated Factor 15 (PAF15) as a Specific Ubiquitination Target of UHRF1 in Embryonic Stem Cells
Karg, Elisabeth, Smets, Martha, Ryan, Joel, Forné, Ignasi, Qin, Weihua, Mulholland, Christopher B., Kalideris, Georgia, Imhof, Axel, Bultmann, Sebastian, Leonhardt, Heinrich
Published in Journal of molecular biology (08.12.2017)
Published in Journal of molecular biology (08.12.2017)
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Journal Article
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation
Stolz, Paul, Mantero, Angelo Salazar, Tvardovskiy, Andrey, Ugur, Enes, Wange, Lucas E, Mulholland, Christopher B, Cheng, Yuying, Wierer, Michael, Enard, Wolfgang, Schneider, Robert, Bartke, Till, Leonhardt, Heinrich, Elsässer, Simon J, Bultmann, Sebastian
Published in Nucleic acids research (26.08.2022)
Published in Nucleic acids research (26.08.2022)
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Journal Article
Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency
Qin, Weihua, Ugur, Enes, Mulholland, Christopher B, Bultmann, Sebastian, Solovei, Irina, Modic, Miha, Smets, Martha, Wierer, Michael, Forné, Ignasi, Imhof, Axel, Cardoso, M Cristina, Leonhardt, Heinrich
Published in Nucleic acids research (21.07.2021)
Published in Nucleic acids research (21.07.2021)
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Journal Article
Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency
Mulholland, Christopher B., Traube, Franziska R., Ugur, Enes, Parsa, Edris, Eckl, Eva-Maria, Schönung, Maximilian, Modic, Miha, Bartoschek, Michael D., Stolz, Paul, Ryan, Joel, Carell, Thomas, Leonhardt, Heinrich, Bultmann, Sebastian
Published in Scientific reports (21.07.2020)
Published in Scientific reports (21.07.2020)
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Journal Article
A modular open platform for systematic functional studies under physiological conditions
Mulholland, Christopher B, Smets, Martha, Schmidtmann, Elisabeth, Leidescher, Susanne, Markaki, Yolanda, Hofweber, Mario, Qin, Weihua, Manzo, Massimiliano, Kremmer, Elisabeth, Thanisch, Katharina, Bauer, Christina, Rombaut, Pascaline, Herzog, Franz, Leonhardt, Heinrich, Bultmann, Sebastian
Published in Nucleic acids research (30.09.2015)
Published in Nucleic acids research (30.09.2015)
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Journal Article
Author Correction: Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
Mulholland, Christopher B., Nishiyama, Atsuya, Ryan, Joel, Nakamura, Ryohei, Yiğit, Merve, Glück, Ivo M., Trummer, Carina, Qin, Weihua, Bartoschek, Michael D., Traube, Franziska R., Parsa, Edris, Ugur, Enes, Modic, Miha, Acharya, Aishwarya, Stolz, Paul, Ziegenhain, Christoph, Wierer, Michael, Enard, Wolfgang, Carell, Thomas, Lamb, Don C., Takeda, Hiroyuki, Nakanishi, Makoto, Bultmann, Sebastian, Leonhardt, Heinrich
Published in Nature communications (17.12.2020)
Published in Nature communications (17.12.2020)
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Journal Article
Regular Nonsteroidal Anti-Inflammatory Drug Use Increases Stress Fracture Risk in the General Population: A Retrospective Case-Control Study
Ciuciu, Alexandra, Mulholland, Christopher, Bozzi, Michael A, Frymoyer, Chris C, Cavinatto, Leonardo, Yaron, David, Harwood, Marc I, Close, Jeremy D, Mehallo, Christopher J, Tomlinson, Ryan E
Published in Advances in orthopedics (12.10.2024)
Published in Advances in orthopedics (12.10.2024)
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Journal Article
Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis
Wenk, Catharina, Garz, Anne-Kathrin, Grath, Sonja, Huberle, Christina, Witham, Denis, Weickert, Marie, Malinverni, Roberto, Niggemeyer, Julia, Kyncl, Michèle, Hecker, Judith, Pagel, Charlotta, Mulholland, Christopher B., Müller-Thomas, Catharina, Leonhardt, Heinrich, Bassermann, Florian, Oostendorp, Robert A.J., Metzeler, Klaus H., Buschbeck, Marcus, Götze, Katharina S.
Published in Blood advances (11.12.2018)
Published in Blood advances (11.12.2018)
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Journal Article
A modular open platform for systematic functional studies under physiological conditions
Mulholland, Christopher B., Smets, Martha, Schmidtmann, Elisabeth, Leidescher, Susanne, Markaki, Yolanda, Hofweber, Mario, Qin, Weihua, Manzo, Massimiliano, Kremmer, Elisabeth, Thanisch, Katharina, Bauer, Christina, Rombaut, Pascaline, Herzog, Franz, Leonhardt, Heinrich, Bultmann, Sebastian
Published in Nucleic acids research (30.09.2015)
Published in Nucleic acids research (30.09.2015)
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Journal Article
Spatial organization of transcribed eukaryotic genes
Leidescher, Susanne, Ribisel, Johannes, Ullrich, Simon, Feodorova, Yana, Hildebrand, Erica, Galitsyna, Alexandra, Bultmann, Sebastian, Link, Stephanie, Thanisch, Katharina, Mulholland, Christopher, Dekker, Job, Leonhardt, Heinrich, Mirny, Leonid, Solovei, Irina
Published in Nature cell biology (01.03.2022)
Published in Nature cell biology (01.03.2022)
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Journal Article
Azacitidine Directly Acts on the Mesenchymal Stromal Cell Compartment in Myelodysplastic Syndromes to Alter Niche Function and Suppress Malignant Hematopoeitic Stem/Progenitor Cells
Wenk, Catharina, Garz, Anne-Kathrin, Huberle, Christina, Grath, Sonja, Witham, Denis, Weickert, Marie, Niggemeyer, Julia, Hecker, Judith, Kyncl, Michele, Müller-Thomas, Catharina, Mulholland, Christopher, Oostendorp, Robert A.J., Metzeler, Klaus H., Peschel, Christian, Götze, Katharina S
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger
Hata, Keiichi, Kobayashi, Naohiro, Sugimura, Keita, Qin, Weihua, Deis Haxholli, Chiba, Yoshie, Yoshimi, Sae, Hayashi, Gosuke, Onoda, Hiroki, Ikegami, Takahisa, Mulholland, Christopher B, Nishiyama, Atsuya, Nakanishi, Makoto, Leonhardt, Heinrich, Konuma, Tsuyoshi, Arita, Kyohei
Published in bioRxiv (04.10.2022)
Published in bioRxiv (04.10.2022)
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Paper
Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation
Modic, Miha, Igor Ruiz De Los Mozos, Steinhauser, Sebastian, Emiel Van Genderen, Schirge, Silvia, Bergant, Valter, Ryan, Joel, Mulholland, Christopher B, Faraway, Rupert, Lee, Flora C Y, Klobučar, Tajda, Merl-Pham, Juliane, Hauck, Stephanie M, Drukker, Micha, Bultmann, Sebastian, Leonhardt, Heinrich, Lickert, Heiko, Luscombe, Nicholas M, Derk Ten Berge, Ule, Jernej
Published in bioRxiv (16.03.2021)
Published in bioRxiv (16.03.2021)
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Paper
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive demethylation in mammals
Mulholland, Christopher B, Nishiyama, Atsuya, Ryan, Joel, Nakamura, Ryohei, Yigit, Merve, Glueck, Ivo M, Trummer, Carina, Qin, Weihua, Bartoschek, Michael D, Traube, Franziska R, Parsa, Edris, Enes Ugur, Modic, Miha, Acharya, Aishwarya, Stolz, Paul, Ziegenhain, Christoph, Wierer, Michael, Enard, Wolfgang, Carell, Thomas, Lamb, Don C, Takeda, Hiroyuki, Nakanashi, Makoto, Bultmann, Sebastian, Leonhardt, Heinrich
Published in bioRxiv (04.04.2020)
Published in bioRxiv (04.04.2020)
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Paper
Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency
Mulholland, Christopher B, Traube, Franziska R, Parsa, Edris, Eckl, Eva-Maria, Schoenung, Maximillian, Modic, Miha, Bartoschek, Michael D, Stolz, Paul, Ryan, Joel, Carell, Thomas, Leonhardt, Heinrich, Bultmann, Sebastian
Published in bioRxiv (13.03.2018)
Published in bioRxiv (13.03.2018)
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Paper