Azetidine-2,4-diones (4-Oxo-β-lactams) as Scaffolds for Designing Elastase Inhibitors
Mulchande, Jalmira, Guedes, Rita C, Tsang, Wing-Yin, Page, Michael I, Moreira, Rui, Iley, Jim
Published in Journal of medicinal chemistry (27.03.2008)
Published in Journal of medicinal chemistry (27.03.2008)
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Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking
Hofbauer, Stefan, Brito, José A., Mulchande, Jalmira, Nogly, Przemyslaw, Pessanha, Miguel, Moreira, Rui, Archer, Margarida
Published in Acta crystallographica. Section F, Structural biology communications (01.10.2015)
Published in Acta crystallographica. Section F, Structural biology communications (01.10.2015)
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Journal Article
The efficiency of C-4 substituents in activating the beta-lactam scaffold towards serine proteases and hydroxide ion
Mulchande, Jalmira, Martins, Luisa, Moreira, Rui, Archer, Margarida, Oliveira, Tania F., Iley, Jim
Published in Organic & biomolecular chemistry (01.01.2007)
Published in Organic & biomolecular chemistry (01.01.2007)
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Synthesis, stability, biochemical and pharmacokinetic properties of a new potent and selective 4-oxo-β-lactam inhibitor of human leukocyte elastase
Mulchande, Jalmira, Simões, Sandra I., Gaspar, Maria M., Eleutério, Carla V., Oliveira, Rudi, Cruz, Maria E.M., Moreira, Rui, Iley, Jim
Published in Journal of enzyme inhibition and medicinal chemistry (01.04.2011)
Published in Journal of enzyme inhibition and medicinal chemistry (01.04.2011)
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