Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis
Sarhan, Joseph, Liu, Beiyun C, Muendlein, Hayley I, Weindel, Chi G, Smirnova, Irina, Tang, Amy Y, Ilyukha, Vladimir, Sorokin, Maxim, Buzdin, Anton, Fitzgerald, Katherine A, Poltorak, Alexander
Published in Cell death and differentiation (01.02.2019)
Published in Cell death and differentiation (01.02.2019)
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Journal Article
ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1
Muendlein, Hayley I, Connolly, Wilson M, Magri, Zoie, Smirnova, Irina, Ilyukha, Vladimir, Gautam, Avishekh, Degterev, Alexei, Poltorak, Alexander
Published in Nature communications (04.01.2021)
Published in Nature communications (04.01.2021)
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Journal Article
Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses
Liu, Beiyun C., Sarhan, Joseph, Panda, Alexander, Muendlein, Hayley I., Ilyukha, Vladimir, Coers, Jörn, Yamamoto, Masahiro, Isberg, Ralph R., Poltorak, Alexander
Published in Cell reports (Cambridge) (03.07.2018)
Published in Cell reports (Cambridge) (03.07.2018)
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Journal Article
Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
Jetton, David, Muendlein, Hayley I., Connolly, Wilson M., Magri, Zoie, Smirnova, Irina, Batorsky, Rebecca, Mecsas, Joan, Degterev, Alexei, Poltorak, Alexander
Published in Cell reports (Cambridge) (27.08.2024)
Published in Cell reports (Cambridge) (27.08.2024)
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Journal Article
Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation
Muendlein, Hayley I., Sarhan, Joseph, Liu, Beiyun C., Connolly, Wilson M., Schworer, Stephen A., Smirnova, Irina, Tang, Amy Y., Ilyukha, Vladimir, Pietruska, Jodie, Tahmasebi, Soroush, Sonenberg, Nahum, Degterev, Alexei, Poltorak, Alexander
Published in Cell reports (Cambridge) (21.01.2020)
Published in Cell reports (Cambridge) (21.01.2020)
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Journal Article
Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
Sarhan, Joseph, Liu, Beiyun C., Muendlein, Hayley I., Li, Peng, Nilson, Rachael, Tang, Amy Y., Rongvaux, Anthony, Bunnell, Stephen C., Shao, Feng, Green, Douglas R., Poltorak, Alexander
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2018)
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Journal Article
cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
Muendlein, Hayley I, Jetton, David, Connolly, Wilson M, Eidell, Keith P, Magri, Zoie, Smirnova, Irina, Poltorak, Alexander
Published in Science (American Association for the Advancement of Science) (20.03.2020)
Published in Science (American Association for the Advancement of Science) (20.03.2020)
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Journal Article
ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF
Muendlein, Hayley I, Connolly, Wilson M, Magri, Zoie, Jetton, David, Smirnova, Irina, Degterev, Alexei, Balachandran, Siddharth, Poltorak, Alexander
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2022)
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Journal Article
CD14 is a decision-maker between Fas-mediated death and inflammation
Magri, Zoie, Jetton, David, Muendlein, Hayley I., Connolly, Wilson M., Russell, Hunter, Smirnova, Irina, Sharma, Shruti, Bunnell, Stephen, Poltorak, Alexander
Published in Cell reports (Cambridge) (24.09.2024)
Published in Cell reports (Cambridge) (24.09.2024)
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Journal Article
cFLIP L protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
Muendlein, Hayley I, Jetton, David, Connolly, Wilson M, Eidell, Keith P, Magri, Zoie, Smirnova, Irina, Poltorak, Alexander
Published in Science (American Association for the Advancement of Science) (20.03.2020)
Published in Science (American Association for the Advancement of Science) (20.03.2020)
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Journal Article
LFA-1 and kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motors
Eidell, Keith P., Lovy, Alenka, Sylvain, Nicholas R., Scangarello, Frank A., Muendlein, Hayley I., Ophir, Michael J., Nguyen, Ken, Seminario, Maria-Cristina, Bunnell, Stephen C.
Published in Journal of cell science (15.08.2021)
Published in Journal of cell science (15.08.2021)
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Journal Article
Neutrophils and macrophages drive TNF-induced lethality via TRIF/CD14-mediated responses
Muendlein, Hayley I, Connolly, Wilson M, Cameron, James, Jetton, David, Magri, Zoie, Smirnova, Irina, Vannier, Edouard, Li, Xudong, Martinot, Amanda J, Batorsky, Rebecca, Poltorak, Alexander
Published in Science immunology (23.12.2022)
Published in Science immunology (23.12.2022)
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