Enterohemorrhagic Escherichia coli and a Fresh View on Shiga Toxin-Binding Glycosphingolipids of Primary Human Kidney and Colon Epithelial Cells and Their Toxin Susceptibility
Detzner, Johanna, Pohlentz, Gottfried, Müthing, Johannes
Published in International journal of molecular sciences (21.06.2022)
Published in International journal of molecular sciences (21.06.2022)
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MALDI‑2 Mass Spectrometry and Immunohistochemistry Imaging of Gb3Cer, Gb4Cer, and Further Glycosphingolipids in Human Colorectal Cancer Tissue
Bien, Tanja, Perl, Markus, Machmüller, Andrea C, Nitsche, Ulrich, Conrad, Anja, Johannes, Ludger, Müthing, Johannes, Soltwisch, Jens, Janssen, Klaus-Peter, Dreisewerd, Klaus
Published in Analytical chemistry (Washington) (19.05.2020)
Published in Analytical chemistry (Washington) (19.05.2020)
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Combining Mass Spectrometry, Surface Acoustic Wave Interaction Analysis, and Cell Viability Assays for Characterization of Shiga Toxin Subtypes of Pathogenic Escherichia coli Bacteria
Steil, Daniel, Pohlentz, Gottfried, Legros, Nadine, Mormann, Michael, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Published in Analytical chemistry (Washington) (07.08.2018)
Published in Analytical chemistry (Washington) (07.08.2018)
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RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells
Kouzel, Ivan U, Kehl, Alexander, Berger, Petya, Liashkovich, Ivan, Steil, Daniel, Makalowski, Wojciech, Suzuki, Yutaka, Pohlentz, Gottfried, Karch, Helge, Mellmann, Alexander, Müthing, Johannes
Published in Scientific reports (18.03.2020)
Published in Scientific reports (18.03.2020)
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MALDI Mass Spectrometry Imaging of Bioactive Lipids in Mouse Brain with a Synapt G2‑S Mass Spectrometer Operated at Elevated Pressure: Improving the Analytical Sensitivity and the Lateral Resolution to Ten Micrometers
Kettling, Hans, Vens-Cappell, Simeon, Soltwisch, Jens, Pirkl, Alexander, Haier, Jörg, Müthing, Johannes, Dreisewerd, Klaus
Published in Analytical chemistry (Washington) (05.08.2014)
Published in Analytical chemistry (Washington) (05.08.2014)
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Label-free quantitative cell division monitoring of endothelial cells by digital holographic microscopy
Kemper, Bjrn, Bauwens, Andreas, Vollmer, Angelika, Ketelhut, Steffi, Langehanenberg, Patrik, Muthing, Johannes, Karch, Helge, von Bally, Gert
Published in Journal of Biomedical Optics (01.05.2010)
Published in Journal of Biomedical Optics (01.05.2010)
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On-Tissue Phospholipase C Digestion for Enhanced MALDI-MS Imaging of Neutral Glycosphingolipids
Vens-Cappell, Simeon, Kouzel, Ivan U, Kettling, Hans, Soltwisch, Jens, Bauwens, Andreas, Porubsky, Stefan, Müthing, Johannes, Dreisewerd, Klaus
Published in Analytical chemistry (Washington) (07.06.2016)
Published in Analytical chemistry (Washington) (07.06.2016)
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How bacterial pathogens of the gastrointestinal tract use the mucosal glyco-code to harness mucus and microbiota: New ways to study an ancient bag of tricks
Josenhans, Christine, Müthing, Johannes, Elling, Lothar, Bartfeld, Sina, Schmidt, Herbert
Published in International journal of medical microbiology (01.02.2020)
Published in International journal of medical microbiology (01.02.2020)
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Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure
Porubsky, Stefan, Federico, Giuseppina, Müthing, Johannes, Jennemann, Richard, Gretz, Norbert, Büttner, Stefan, Obermüller, Nicholas, Jung, Oliver, Hauser, Ingeborg A, Gröne, Elisabeth, Geiger, Helmut, Gröne, Hermann-Josef, Betz, Christoph
Published in The Journal of pathology (01.09.2014)
Published in The Journal of pathology (01.09.2014)
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Shiga toxin of enterohaemorrhagic Escherichia coli directly injures developing human erythrocytes
Betz, Josefine, Dorn, Isabel, Kouzel, Ivan U., Bauwens, Andreas, Meisen, Iris, Kemper, Björn, Bielaszewska, Martina, Mormann, Michael, Weymann, Lena, Sibrowski, Walter, Karch, Helge, Schlenke, Peter, Müthing, Johannes
Published in Cellular microbiology (01.10.2016)
Published in Cellular microbiology (01.10.2016)
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Primary Human Colon Epithelial Cells (pHCoEpiCs) Do Express the Shiga Toxin (Stx) Receptor Glycosphingolipids Gb3Cer and Gb4Cer and Are Largely Refractory but Not Resistant towards Stx
Detzner, Johanna, Püttmann, Charlotte, Pohlentz, Gottfried, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Published in International journal of molecular sciences (16.09.2021)
Published in International journal of molecular sciences (16.09.2021)
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Blockade of Glycosphingolipid Synthesis Inhibits Cell Cycle and Spheroid Growth of Colon Cancer Cells In Vitro and Experimental Colon Cancer Incidence In Vivo
Jennemann, Richard, Volz, Martina, Bestvater, Felix, Schmidt, Claudia, Richter, Karsten, Kaden, Sylvia, Müthing, Johannes, Gröne, Hermann-Josef, Sandhoff, Roger
Published in International journal of molecular sciences (01.10.2021)
Published in International journal of molecular sciences (01.10.2021)
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Shiga toxins, glycosphingolipid diversity, and endothelial cell injury
Müthing, Johannes, Schweppe, Christian H, Karch, Helge, Friedrich, Alexander W
Published in Thrombosis and haemostasis (01.02.2009)
Published in Thrombosis and haemostasis (01.02.2009)
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Shiga Toxin (Stx)-Binding Glycosphingolipids of Primary Human Renal Cortical Epithelial Cells (pHRCEpiCs) and Stx-Mediated Cytotoxicity
Detzner, Johanna, Krojnewski, Elisabeth, Pohlentz, Gottfried, Steil, Daniel, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Published in Toxins (12.02.2021)
Published in Toxins (12.02.2021)
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Progress in Detection and Structural Characterization of Glycosphingolipids in Crude Lipid Extracts by Enzymatic Phospholipid Disintegration Combined with Thin-Layer Chromatography Immunodetection and IR-MALDI Mass Spectrometry
Kouzel, Ivan U, Pirkl, Alexander, Pohlentz, Gottfried, Soltwisch, Jens, Dreisewerd, Klaus, Karch, Helge, Müthing, Johannes
Published in Analytical chemistry (Washington) (21.01.2014)
Published in Analytical chemistry (Washington) (21.01.2014)
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Shiga toxin glycosphingolipid receptors of Vero-B4 kidney epithelial cells and their membrane microdomain lipid environment1
Steil, Daniel, Schepers, Catherine-Louise, Pohlentz, Gottfried, Legros, Nadine, Runde, Jana, Humpf, Hans-Ulrich, Karch, Helge, Müthing, Johannes
Published in Journal of lipid research (01.12.2015)
Published in Journal of lipid research (01.12.2015)
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Primary Human Renal Proximal Tubular Epithelial Cells (pHRPTEpiCs): Shiga Toxin (Stx) Glycosphingolipid Receptors, Stx Susceptibility, and Interaction with Membrane Microdomains
Detzner, Johanna, Klein, Anna-Lena, Pohlentz, Gottfried, Krojnewski, Elisabeth, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Published in Toxins (28.07.2021)
Published in Toxins (28.07.2021)
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