An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function
Cuesta-Hernández, Hipólito Nicolás, Contreras, Julia, Soriano-Maldonado, Pablo, Sánchez-Wandelmer, Jana, Yeung, Wayland, Martín-Hurtado, Ana, Muñoz, Inés G., Kannan, Natarajan, Llimargas, Marta, Muñoz, Javier, Plaza-Menacho, Iván
Published in Nature communications (17.10.2023)
Published in Nature communications (17.10.2023)
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Journal Article
Recommendations for the classification of germline variants in the exonuclease domain of POLE and POLD1
Mur, Pilar, Viana-Errasti, Julen, García-Mulero, Sandra, Magraner-Pardo, Lorena, Muéoz, Inés G, Pons, Tirso, Capellá, Gabriel, Pineda, Marta, Feliubadaló, Lidia, Valle, Laura
Published in Genome medicine (17.10.2023)
Published in Genome medicine (17.10.2023)
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Journal Article
Molecular basis of the final step of cell division in Streptococcus pneumoniae
Martínez-Caballero, Siseth, Freton, Céline, Molina, Rafael, Bartual, Sergio G., Gueguen-Chaignon, Virginie, Mercy, Chryslène, Gago, Federico, Mahasenan, Kiran V., Muñoz, Inés G., Lee, Mijoon, Hesek, Dusan, Mobashery, Shahriar, Hermoso, Juan A., Grangeasse, Christophe
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Journal Article
Molecular basis of Tousled-Like Kinase 2 activation
Mortuza, Gulnahar B., Hermida, Dario, Pedersen, Anna-Kathrine, Segura-Bayona, Sandra, López-Méndez, Blanca, Redondo, Pilar, Rüther, Patrick, Pozdnyakova, Irina, Garrote, Ana M., Muñoz, Inés G., Villamor-Payà, Marina, Jauset, Cristina, Olsen, Jesper V., Stracker, Travis H., Montoya, Guillermo
Published in Nature communications (28.06.2018)
Published in Nature communications (28.06.2018)
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Journal Article
Homing endonucleases: from basics to therapeutic applications
Marcaida, Maria J, Muñoz, Inés G, Blanco, Francisco J, Prieto, Jesús, Montoya, Guillermo
Published in Cellular and molecular life sciences : CMLS (01.03.2010)
Published in Cellular and molecular life sciences : CMLS (01.03.2010)
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Journal Article
Small molecule MMRi62 targets MDM4 for degradation and induces leukemic cell apoptosis regardless of p53 status
Lama, Rati, Xu, Chao, Galster, Samuel L, Querol-García, Javier, Portwood, Scott, Mavis, Cory K, Ruiz, Federico M, Martin, Diana, Wu, Jin, Giorgi, Marianna C, Bargonetti, Jill, Wang, Eunice S, Hernandez-Ilizaliturri, Francisco J, Koudelka, Gerald B, Chemler, Sherry R, Muñoz, Inés G, Wang, Xinjiang
Published in Frontiers in oncology (05.08.2022)
Published in Frontiers in oncology (05.08.2022)
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Journal Article
Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus, an essential component of the divisome machinery
Martínez-Caballero, Siseth, Mahasenan, Kiran V., Kim, Choon, Molina, Rafael, Feltzer, Rhona, Lee, Mijoon, Bouley, Renee, Hesek, Dusan, Fisher, Jed F., Muñoz, Inés G., Chang, Mayland, Mobashery, Shahriar, Hermoso, Juan A.
Published in Computational and structural biotechnology journal (01.01.2021)
Published in Computational and structural biotechnology journal (01.01.2021)
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Journal Article
Activation of Nucleoplasmin, an Oligomeric Histone Chaperone, Challenges Its Stability
Taneva, Stefka G, Muñoz, Inés G, Franco, Guillermo, Falces, Jorge, Arregi, Igor, Muga, Arturo, Montoya, Guillermo, Urbaneja, María A, Bañuelos, Sonia
Published in Biochemistry (Easton) (30.12.2008)
Published in Biochemistry (Easton) (30.12.2008)
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Journal Article
A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity
Compte, Marta, Harwood, Seandean Lykke, Muñoz, Ines G., Navarro, Rocio, Zonca, Manuela, Perez-Chacon, Gema, Erce-Llamazares, Ainhoa, Merino, Nekane, Tapia-Galisteo, Antonio, Cuesta, Angel M., Mikkelsen, Kasper, Caleiras, Eduardo, Nuñez-Prado, Natalia, Aznar, M. Angela, Lykkemark, Simon, Martínez-Torrecuadrada, Jorge, Melero, Ignacio, Blanco, Francisco J., Bernardino de la Serna, Jorge, Zapata, Juan M., Sanz, Laura, Alvarez-Vallina, Luis
Published in Nature communications (15.11.2018)
Published in Nature communications (15.11.2018)
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Journal Article
Family 7 cellobiohydrolases from Phanerochaete chrysosporium: crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 Å resolution and homology models of the isozymes
Muñoz, Inés G, Ubhayasekera, Wimal, Henriksson, Hongbin, Szabó, Istvan, Pettersson, Göran, Johansson, Gunnar, Mowbray, Sherry L, Ståhlberg, Jerry
Published in Journal of molecular biology (14.12.2001)
Published in Journal of molecular biology (14.12.2001)
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Journal Article
An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity
Compte, Marta, Harwood, Seandean L, Erce-Llamazares, Ainhoa, Tapia-Galisteo, Antonio, Romero, Eduardo, Ferrer, Irene, Garrido-Martin, Eva M, Enguita, Ana B, Ochoa, Maria C, Blanco, Belén, Oteo, Marta, Merino, Nekane, Nehme-Álvarez, Daniel, Hangiu, Oana, Domínguez-Alonso, Carmen, Zonca, Manuela, Ramírez-Fernández, Angel, Blanco, Francisco J, Morcillo, Miguel A, Muñoz, Ines G, Melero, Ignacio, Rodriguez-Peralto, José L, Paz-Ares, Luis, Sanz, Laura, Alvarez-Vallina, Luis
Published in Clinical cancer research (01.06.2021)
Published in Clinical cancer research (01.06.2021)
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Journal Article
Three-dimensional Crystal Structure and Enzymic Characterization of β-Mannanase Man5A from Blue Mussel Mytilus edulis
Larsson, Anna M., Anderson, Lars, Xu, Bingze, Muñoz, Inés G., Usón, Isabel, Janson, Jan-Christer, Stålbrand, Henrik, Ståhlberg, Jerry
Published in Journal of molecular biology (14.04.2006)
Published in Journal of molecular biology (14.04.2006)
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Journal Article
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases
Blanco, Francisco J, Prieto, Jesús, Arnould, Sylvain, Daboussi, Fayza, Redondo, Pilar, Perez, Christophe, Muñoz, Inés G, Duchateau, Philippe, Pâques, Frédéric, Alibés, Andreu, Montoya, Guillermo, Stricher, Francois, Serrano, Luis, Cabaniols, Jean-Pierre
Published in Nature (06.11.2008)
Published in Nature (06.11.2008)
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Journal Article
Chaperonins: two rings for folding
Yébenes, Hugo, Mesa, Pablo, Muñoz, Inés G., Montoya, Guillermo, Valpuesta, José M.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.08.2011)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.08.2011)
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Journal Article
Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin
Valpuesta, José M, Montoya, Guillermo, Muñoz, Inés G, Yébenes, Hugo, Zhou, Min, Mesa, Pablo, Serna, Marina, Park, Ah Young, Bragado-Nilsson, Elisabeth, Beloso, Ana, de Cárcer, Guillermo, Malumbres, Marcos, Robinson, Carol V
Published in Nature structural & molecular biology (01.01.2011)
Published in Nature structural & molecular biology (01.01.2011)
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Journal Article
Structural basis of PcsB-mediated cell separation in Streptococcus pneumoniae
Bartual, Sergio G., Straume, Daniel, Stamsås, Gro Anita, Muñoz, Inés G., Alfonso, Carlos, Martínez-Ripoll, Martín, Håvarstein, Leiv Sigve, Hermoso, Juan A.
Published in Nature communications (08.05.2014)
Published in Nature communications (08.05.2014)
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Journal Article
Structural and biochemical insights into an engineered high-redox potential laccase overproduced in Aspergillus
de Salas, Felipe, Cañadas, Rubén, Santiago, Gerard, Virseda-Jerez, Alicia, Vind, Jesper, Gentili, Patrizia, Martínez, Angel T., Guallar, Víctor, Muñoz, Inés G., Camarero, Susana
Published in International journal of biological macromolecules (01.12.2019)
Published in International journal of biological macromolecules (01.12.2019)
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Journal Article
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Muñoz, Inés G, Prieto, Jesús, Subramanian, Sunita, Coloma, Javier, Redondo, Pilar, Villate, Maider, Merino, Nekane, Marenchino, Marco, D'Abramo, Marco, Gervasio, Francesco L, Grizot, Sylvestre, Daboussi, Fayza, Smith, Julianne, Chion-Sotinel, Isabelle, Pâques, Frédéric, Duchateau, Philippe, Alibés, Andreu, Stricher, François, Serrano, Luis, Blanco, Francisco J, Montoya, Guillermo
Published in Nucleic acids research (01.01.2011)
Published in Nucleic acids research (01.01.2011)
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Journal Article