SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape
Cele, Sandile, Karim, Farina, Lustig, Gila, San, James Emmanuel, Hermanus, Tandile, Tegally, Houriiyah, Snyman, Jumari, Moyo-Gwete, Thandeka, Wilkinson, Eduan, Bernstein, Mallory, Khan, Khadija, Hwa, Shi-Hsia, Tilles, Sasha W., Singh, Lavanya, Giandhari, Jennifer, Mthabela, Ntombifuthi, Mazibuko, Matilda, Ganga, Yashica, Gosnell, Bernadett I., Karim, Salim S. Abdool, Hanekom, Willem, Van Voorhis, Wesley C., Ndung’u, Thumbi, Lessells, Richard J., Moore, Penny L., Moosa, Mahomed-Yunus S., de Oliveira, Tulio, Sigal, Alex
Published in Cell host & microbe (09.02.2022)
Published in Cell host & microbe (09.02.2022)
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Journal Article
HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway
Krause, Robert, Snyman, Jumari, Shi-Hsia, Hwa, Muema, Daniel, Karim, Farina, Ganga, Yashica, Ngoepe, Abigail, Zungu, Yenzekile, Gazy, Inbal, Bernstein, Mallory, Khan, Khadija, Mazibuko, Matilda, Mthabela, Ntombifuthi, Ramjit, Dirhona, Limbo, Oliver, Jardine, Joseph, Sok, Devin, Wilson, Ian A, Hanekom, Willem, Sigal, Alex, Kløverpris, Henrik, Ndung'u, Thumbi, Leslie, Alasdair
Published in eLife (27.10.2022)
Published in eLife (27.10.2022)
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Journal Article
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave
Karim, Farina, Gazy, Inbal, Cele, Sandile, Zungu, Yenzekile, Krause, Robert, Bernstein, Mallory, Khan, Khadija, Ganga, Yashica, Rodel, Hylton, Mthabela, Ntombifuthi, Mazibuko, Matilda, Muema, Daniel, Ramjit, Dirhona, Ndung'u, Thumbi, Hanekom, Willem, Gosnell, Bernadett, Lessells, Richard J, Wong, Emily B, de Oliveira, Tulio, Moosa, Mahomed-Yunus S, Lustig, Gil, Leslie, Alasdair, Kløverpris, Henrik, Sigal, Alex
Published in eLife (05.10.2021)
Published in eLife (05.10.2021)
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Journal Article
HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control
Fardoos, Rabiah, Nyquist, Sarah K., Asowata, Osaretin E., Kazer, Samuel W., Singh, Alveera, Ngoepe, Abigail, Giandhari, Jennifer, Mthabela, Ntombifuthi, Ramjit, Dirhona, Singh, Samita, Karim, Farina, Buus, Søren, Anderson, Frank, Porterfield, J. Zachary, Sibiya, Andile L., Bipath, Rishan, Moodley, Kumeshan, Kuhn, Warren, Berger, Bonnie, Nguyen, Son, de Oliveira, Tulio, Ndung’u, Thumbi, Goulder, Philip, Shalek, Alex K., Leslie, Alasdair, Kløverpris, Henrik N.
Published in Frontiers in immunology (18.10.2022)
Published in Frontiers in immunology (18.10.2022)
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Journal Article
Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection
Asowata, Osaretin E, Singh, Alveera, Ngoepe, Abigail, Herbert, Nicholas, Fardoos, Rabiah, Reddy, Kavidha, Zungu, Yenzekile, Nene, Faith, Mthabela, Ntombifuthi, Ramjit, Dirhona, Karim, Farina, Govender, Katya, Ndung'u, Thumbi, Porterfield, J Zachary, Adamson, John H, Madela, Fusi G, Manzini, Vukani T, Anderson, Frank, Leslie, Alasdair, Kløverpris, Henrik N
Published in JCI insight (22.11.2021)
Published in JCI insight (22.11.2021)
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Journal Article
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells
Fardoos, Rabiah, Asowata, Osaretin E., Herbert, Nicholas, Nyquist, Sarah K., Zungu, Yenzekile, Singh, Alveera, Ngoepe, Abigail, Mbano, Ian M., Mthabela, Ntombifuthi, Ramjit, Dirhona, Karim, Farina, Kuhn, Warren, Madela, Fusi G., Manzini, Vukani T., Anderson, Frank, Berger, Bonnie, Pers, Tune H., Shalek, Alex K., Leslie, Alasdair, Kløverpris, Henrik N.
Published in JCI insight (23.08.2021)
Published in JCI insight (23.08.2021)
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Journal Article
Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave
Snyman, Jumari, Hwa, Shi Hsia, Krause, Robert, Muema, Daniel, Reddy, Tarylee, Ganga, Yashica, Karim, Farina, Leslie, Alasdair, Sigal, Alex, Ndung’u, Thumbi
Published in Clinical infectious diseases (24.08.2022)
Published in Clinical infectious diseases (24.08.2022)
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Journal Article
Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Ad26.CoV2.S Vaccination in People Living With Human Immunodeficiency Virus (HIV)
Khan, Khadija, Lustig, Gila, Bernstein, Mallory, Archary, Derseree, Cele, Sandile, Karim, Farina, Smith, Muneerah, Ganga, Yashica, Jule, Zesuliwe, Reedoy, Kajal, Miya, Yoliswa, Mthabela, Ntombifuthi, Magula, Nombulelo P, Lessells, Richard, de Oliveira, Tulio, Gosnell, Bernadett I, Abdool Karim, Salim, Garrett, Nigel, Hanekom, Willem, Bekker, Linda-Gail, Gray, Glenda, Blackburn, Jonathan M, Moosa, Mahomed-Yunus S, Sigal, Alex
Published in Clinical infectious diseases (24.08.2022)
Published in Clinical infectious diseases (24.08.2022)
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Journal Article
HIV specific CD8 + T RM -like cells in tonsils express exhaustive signatures in the absence of natural HIV control
Fardoos, Rabiah, Nyquist, Sarah K, Asowata, Osaretin E, Kazer, Samuel W, Singh, Alveera, Ngoepe, Abigail, Giandhari, Jennifer, Mthabela, Ntombifuthi, Ramjit, Dirhona, Singh, Samita, Karim, Farina, Buus, Søren, Anderson, Frank, Porterfield, J Zachary, Sibiya, Andile L, Bipath, Rishan, Moodley, Kumeshan, Kuhn, Warren, Berger, Bonnie, Nguyen, Son, de Oliveira, Tulio, Ndung'u, Thumbi, Goulder, Philip, Shalek, Alex K, Leslie, Alasdair, Kløverpris, Henrik N
Published in Frontiers in immunology (2022)
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Published in Frontiers in immunology (2022)
Journal Article
Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant
Khan, Khadija, Karim, Farina, Cele, Sandile, San, James Emmanuel, Lustig, Gila, Tegally, Houriiyah, Rosenberg, Yuval, Bernstein, Mallory, Ganga, Yashica, Jule, Zesuliwe, Reedoy, Kajal, Ngcobo, Nokuthula, Miya, Yoliswa, Mazibuko, Matilda, Mthabela, Ntombifuthi, Mhlane, Zoey, Mbatha, Nikiwe, Giandhari, Jennifer, Ramphal, Yajna, Naidoo, Taryn, Manickchund, Nithendra, Magula, Nombulelo, Karim, Salim Abdool, Gray, Glenda, Hanekom, Willem, von Gottberg, Anne, Milo, Ron, Gosnell, Bernadett, Lessells, Richard, de Oliveira, Tulio, Moore, Penny, Moosa, Yunus S, Sigal, Alex
Published in medRxiv : the preprint server for health sciences (28.01.2022)
Published in medRxiv : the preprint server for health sciences (28.01.2022)
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Journal Article
SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity
Cele, Sandile, Karim, Farina, Lustig, Gila, San, James Emmanuel, Hermanus, Tandile, Tegally, Houriiyah, Snyman, Jumari, Moyo-Gwete, Thandeka, Wilkinson, Eduan, Bernstein, Mallory, Khan, Khadija, Hwa, Shi-Hsia, Tilles, Sasha W, Singh, Lavanya, Giandhari, Jennifer, Mthabela, Ntombifuthi, Mazibuko, Matilda, Ganga, Yashica, Gosnell, Bernadett I, Karim, Salim Abdool, Hanekom, Willem, Van Voorhis, Wesley C, Ndung'u, Thumbi, Lessells, Richard J, Moore, Penny L, Moosa, Mahomed-Yunus S, de Oliveira, Tulio, Sigal, Alex
Published in medRxiv : the preprint server for health sciences (07.12.2021)
Published in medRxiv : the preprint server for health sciences (07.12.2021)
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