Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease
Peng, Shiyong, Garzon, Diego J, Marchese, Monica, Klein, William, Ginsberg, Stephen D, Francis, Beverly M, Mount, Howard T. J, Mufson, Elliott J, Salehi, Ahmad, Fahnestock, Margaret
Published in The Journal of neuroscience (22.07.2009)
Published in The Journal of neuroscience (22.07.2009)
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The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections
Watts, Joel C, Drisaldi, Bettina, Ng, Vivian, Yang, Jing, Strome, Bob, Horne, Patrick, Sy, Man-Sun, Yoong, Larry, Young, Rebecca, Mastrangelo, Peter, Bergeron, Catherine, Fraser, Paul E, Carlson, George A, Mount, Howard TJ, Schmitt-Ulms, Gerold, Westaway, David
Published in The EMBO journal (05.09.2007)
Published in The EMBO journal (05.09.2007)
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Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone
Dhume, Shreya H, Balogun, Kayode, Sarkar, Ambalika, Acosta, Sebastian, Mount, Howard T J, Cahill, Lindsay S, Sled, John G, Serghides, Lena
Published in Frontiers in molecular neuroscience (2024)
Published in Frontiers in molecular neuroscience (2024)
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PPARγ agonists improve survival and neurocognitive outcomes in experimental cerebral malaria and induce neuroprotective pathways in human malaria
Serghides, Lena, McDonald, Chloe R, Lu, Ziyue, Friedel, Miriam, Cui, Cheryl, Ho, Keith T, Mount, Howard T J, Sled, John G, Kain, Kevin C
Published in PLoS pathogens (01.03.2014)
Published in PLoS pathogens (01.03.2014)
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Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease
Auffret, Alexandra, Gautheron, Vanessa, Repici, Mariaelena, Kraftsik, Rudolf, Mount, Howard T. J, Mariani, Jean, Rovira, Catherine
Published in The Journal of neuroscience (12.08.2009)
Published in The Journal of neuroscience (12.08.2009)
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Journal Article
Object recognition memory and BDNF expression are reduced in young TgCRND8 mice
Francis, Beverly M, Kim, John, Barakat, Meredith E, Fraenkl, Stephan, Yücel, Yeni H, Peng, Shiyong, Michalski, Bernadeta, Fahnestock, Margaret, McLaurin, JoAnne, Mount, Howard T.J
Published in Neurobiology of aging (01.03.2012)
Published in Neurobiology of aging (01.03.2012)
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Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related γ-secretase
Sanjo, Nobuo, Katayama, Taiichi, Hasegawa, Hiroshi, Jin, Haifeng, Duthie, Monika, Mount, Howard T.J., Mizusawa, Hidehiro, George-Hyslop, Peter St, Fraser, Paul E.
Published in Neuroscience letters (08.10.2010)
Published in Neuroscience letters (08.10.2010)
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Brain-Derived Neurotrophic Factor Rapidly Enhances Phosphorylation of the Postsynaptic N-methyl-D-Aspartate Receptor Subunit 1
Suen, Piin-Chau, Wu, Kuo, Levine, Eric S., Howard T. J. Mount, Xu, Jia-Ling, Lin, Siang-Yo, Black, Ira B.
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.1997)
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Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model
McLaurin, JoAnne, Kierstead, Meredith E, Brown, Mary E, Hawkes, Cheryl A, Lambermon, Mark H L, Phinney, Amie L, Darabie, Audrey A, Cousins, Julian E, French, Janet E, Lan, Melissa F, Chen, Fusheng, Wong, Sydney S N, Mount, Howard T J, Fraser, Paul E, Westaway, David, George-Hyslop, Peter St
Published in Nature medicine (01.07.2006)
Published in Nature medicine (01.07.2006)
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Journal Article
Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia‐telangiectasia
Mount, Howard T. J., Martel, Jean‐Claude, Fluit, Paul, Wu, Yingji, Gallo‐Hendrikx, Eleanor, Cosi, Cristina, Marien, Marc R.
Published in Journal of neurochemistry (01.03.2004)
Published in Journal of neurochemistry (01.03.2004)
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Interactome Analyses of Mature γ-Secretase Complexes Reveal Distinct Molecular Environments of Presenilin (PS) Paralogs and Preferential Binding of Signal Peptide Peptidase to PS2
Jeon, Amy Hye Won, Böhm, Christopher, Chen, Fusheng, Huo, Hairu, Ruan, Xueying, Ren, Carl He, Ho, Keith, Qamar, Seema, Mathews, Paul M., Fraser, Paul E., Mount, Howard T.J., St George-Hyslop, Peter, Schmitt-Ulms, Gerold
Published in The Journal of biological chemistry (24.05.2013)
Published in The Journal of biological chemistry (24.05.2013)
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Journal Article
Alleles at the Nicastrin Locus Modify Presenilin 1-Deficiency Phenotype
Rozmahel, Richard, Howard T.J. Mount, Chen, Fusheng, Nguyen, Van, Huang, Jean, Erdebil, Serap, Liauw, Jennifer, Yu, Gang, Hasegawa, Hiroshe, Gu, YongJun, Song, You-Qiang, Schmidt, Stephen D., Nixon, Ralph A., Mathews, Paul M., Bergeron, Catherine, Fraser, Paul, Westaway, David, St George-Hyslop, Peter
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2002)
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Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins
Yang, Dun-Sheng, Tandon, Anurag, Chen, Fusheng, Yu, Gang, Yu, Haung, Arawaka, Shigeki, Hasegawa, Hiroshi, Duthie, Monika, Schmidt, Stephen D, Ramabhadran, Triprayer V, Nixon, Ralph A, Mathews, Paul M, Gandy, Samuel E, Mount, Howard T J, St George-Hyslop, Peter, Fraser, Paul E
Published in The Journal of biological chemistry (02.08.2002)
Published in The Journal of biological chemistry (02.08.2002)
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The sedative but not the memory-blocking properties of ethanol are modulated by α5-subunit-containing γ-aminobutyric acid type A receptors
Martin, Loren J., Zurek, Agnieszka A., Bonin, Robert P., Oh, Gabriel H.T., Kim, John H., Mount, Howard T.J., Orser, Beverley A.
Published in Behavioural brain research (01.03.2011)
Published in Behavioural brain research (01.03.2011)
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Journal Article
The sedative but not the memory-blocking properties of ethanol are modulated by alpha 5-subunit-containing gamma -aminobutyric acid type A receptors
Martin, Loren J, Zurek, Agnieszka A, Bonin, Robert P, Oh, Gabriel HT, Kim, John H, Mount, Howard TJ, Orser, Beverley A
Published in Behavioural brain research (01.03.2011)
Published in Behavioural brain research (01.03.2011)
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Journal Article
Glial Cell Line-Derived Neurotrophic Factor Promotes the Survival and Morphologic Differentiation of Purkinje Cells
Howard T. J. Mount, Dean, Deyrick O., Alberch, Jordi, Dreyfus, Cheryl F., Black, Ira B.
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.1995)
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.1995)
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