Immunogenicity of biologically-derived therapeutics: Assessment and interpretation of nonclinical safety studies
Ponce, Rafael, Abad, Leslie, Amaravadi, Lakshmi, Gelzleichter, Thomas, Gore, Elizabeth, Green, James, Gupta, Shalini, Herzyk, Danuta, Hurst, Christopher, Ivens, Inge A., Kawabata, Thomas, Maier, Curtis, Mounho, Barbara, Rup, Bonita, Shankar, Gopi, Smith, Holly, Thomas, Peter, Wierda, Dan
Published in Regulatory toxicology and pharmacology (01.07.2009)
Published in Regulatory toxicology and pharmacology (01.07.2009)
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Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
Lawrence, David, Shahrokh, Zahra, Marsters, Scot, Achilles, Kirsten, Shih, Danny, Mounho, Barbara, Hillan, Kenneth, Totpal, Klara, DeForge, Laura, Schow, Peter, Hooley, Jeffrey, Sherwood, Steve, Pai, Roger, Leung, Susan, Khan, Lolo, Gliniak, Brian, Bussiere, Jeanine, Smith, Craig A, Strom, Stephen S, Kelley, Sean, Fox, Judith A, Thomas, Deborah, Ashkenazi, Avi
Published in Nature medicine (01.04.2001)
Published in Nature medicine (01.04.2001)
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Antitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey
Zuch de Zafra, Christina L, Ashkenazi, Avi, Darbonne, Walter C, Cheu, Melissa, Totpal, Klara, Ortega, Shirley, Flores, Heather, Walker, Mark D, Kabakoff, Bruce, Lum, Bert L, Mounho-Zamora, Barbara J, Marsters, Scot A, Dybdal, Noël O
Published in Cell death & disease (11.08.2016)
Published in Cell death & disease (11.08.2016)
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Uses and Future Applications of Flow Cytometry in Immunotoxicity Testing
Burchiel, Scott W., Lauer, Fredine T., Gurulé, Debbie, Mounho, Barbara J., Salas, Virginia M.
Published in Methods (San Diego, Calif.) (01.09.1999)
Published in Methods (San Diego, Calif.) (01.09.1999)
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Duration of chronic toxicity studies for biotechnology-derived pharmaceuticals: Is 6 months still appropriate?
Clarke, Janet, Hurst, Christopher, Martin, Pauline, Vahle, John, Ponce, Rafael, Mounho, Barbara, Heidel, Shawn, Andrews, Laura, Reynolds, Theresa, Cavagnaro, Joy
Published in Regulatory toxicology and pharmacology (01.02.2008)
Published in Regulatory toxicology and pharmacology (01.02.2008)
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Cytokines: The Good, the Bad, and the Deadly
Ramani, Thulasi, Auletta, Carol S, Weinstock, Daniel, Mounho-Zamora, Barbara, Ryan, Patricia C, Salcedo, Theodora W, Bannish, Gregory
Published in International journal of toxicology (01.07.2015)
Published in International journal of toxicology (01.07.2015)
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Abstract SY03-02: Preclinical assessment of JTX-2011, an agonist antibody targeting ICOS, supports evaluation in ICONIC clinical trial
Michaelson, Jennifer S., Harvey, Christopher, Elpek, Kutlu, Duong, Ellen, Shallberg, Lindsey, Wallace, Matthew, Mabry, Robert, Shu, Jenny, Deshpande, Amit, Zi, Tong, Sazinsky, Stephen, Apgar, Joshua, Mounho-Zamora, Barbara, Briskin, Michael, Trehu, Elizabeth, Reeves, Jason, Hirsch, Heather, Sathyanarayanan, Sriram, Law, Deborah
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Alterations in Human B Cell Calcium Homeostasis by Polycyclic Aromatic Hydrocarbons: Possible Associations with Cytochrome P450 Metabolism and Increased Protein Tyrosine Phosphorylation
Mounho, Barbara J., Burchiel, Scott W.
Published in Toxicology and applied pharmacology (01.03.1998)
Published in Toxicology and applied pharmacology (01.03.1998)
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Concomitant Administration of Bevacizumab, Irinotecan, 5-Fluorouracil, and Leucovorin: Nonclinical Safety and Pharmacokinetics
Gaudreault, Jacques, Shiu, Vanessa, Bricarello, Ann, Christian, Brian J., Zuch, Christina L., Mounho, Barbara
Published in International journal of toxicology (01.09.2005)
Published in International journal of toxicology (01.09.2005)
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Depletion of Glutathione by Benzo(a)pyrene Metabolites, Ionomycin, Thapsigargin, and Phorbol Myristate in Human Peripheral Blood Mononuclear Cells
Romero, David L., Mounho, Barbara J., Lauer, Fredine T., Born, Jerry L., Burchiel, Scott W.
Published in Toxicology and applied pharmacology (01.05.1997)
Published in Toxicology and applied pharmacology (01.05.1997)
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Characterization of Intracellular Calcium Responses Produced by Polycyclic Aromatic Hydrocarbons in Surface Marker-Defined Human Peripheral Blood Mononuclear Cells
Mounho, Barbara J., Davila, Donna R., Burchiel, Scott W.
Published in Toxicology and applied pharmacology (01.08.1997)
Published in Toxicology and applied pharmacology (01.08.1997)
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Journal Article
Safety Assessment of Biotechnology-Derived Therapeutic Drugs
Published in Food Safety of Proteins in Agricultural Biotechnology
(2008)
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