Individualized Dosing of Therapeutic Monoclonal Antibodies—a Changing Treatment Paradigm?
Strik, Anne S., Wang, Yow-Ming C., Ruff, Laura E., Yashar, William, Messmer, Bradley T., Mould, Diane R.
Published in The AAPS journal (05.09.2018)
Published in The AAPS journal (05.09.2018)
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Journal Article
Phase II-I-II Study of Two Different Doses and Schedules of Pralatrexate, a High-Affinity Substrate for the Reduced Folate Carrier, in Patients With Relapsed or Refractory Lymphoma Reveals Marked Activity in T-Cell Malignancies
O'CONNOR, Owen A, HORWITZ, Steven, PATTERSON, Molly, SESHAN, Venkatraman E, SIROTNAK, Frank, FLEISHER, Martin, MOULD, Diane R, SAUNDERS, Mike, ZELENETZ, Andrew D, HAMLIN, Paul, PORTLOCK, Carol, MOSKOWITZ, Craig H, SARASOHN, Debra, NEYLON, Ellen, MASTRELLA, Jill, HAMELERS, Rachel, MACGREGOR-CORTELLI, Barbara
Published in Journal of clinical oncology (10.09.2009)
Published in Journal of clinical oncology (10.09.2009)
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Journal Article
Pharmacokinetic and Pharmacodynamic Effects of Oral CXA‐10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects
Garner, Rachel M., Mould, Diane R., Chieffo, Carla, Jorkasky, Diane K.
Published in Clinical and translational science (01.11.2019)
Published in Clinical and translational science (01.11.2019)
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Journal Article
Approaches to handling missing or “problematic” pharmacology data: Pharmacokinetics
Irby, Donald J., Ibrahim, Mustafa E., Dauki, Anees M., Badawi, Mohamed A., Illamola, Sílvia M., Chen, Mingqing, Wang, Yuhuan, Liu, Xiaoxi, Phelps, Mitch A., Mould, Diane R.
Published in CPT: pharmacometrics and systems pharmacology (01.04.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.04.2021)
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Journal Article
Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non‐small cell lung cancer based on bintrafusp alfa trials
Milenković‐Grišić, Ana‐Marija, Terranova, Nadia, Mould, Diane R., Vugmeyster, Yulia, Mrowiec, Thomas, Machl, Andreas, Girard, Pascal, Venkatakrishnan, Karthik, Khandelwal, Akash
Published in CPT: pharmacometrics and systems pharmacology (01.01.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.01.2024)
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Journal Article
Model Informed Precision Dosing Tool Forecasts Trough Infliximab and Associates with Disease Status and Tumor Necrosis Factor-Alpha Levels of Inflammatory Bowel Diseases
Primas, Christian, Reinisch, Walter, Panetta, John C, Eser, Alexander, Mould, Diane R, Dervieux, Thierry
Published in Journal of clinical medicine (09.06.2022)
Published in Journal of clinical medicine (09.06.2022)
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Journal Article
Appropriateness of Testing for Anti–Tumor Necrosis Factor Agent and Antibody Concentrations, and Interpretation of Results
Melmed, Gil Y, Irving, Peter M, Jones, Jennifer, Kaplan, Gilaad G, Kozuch, Patricia L, Velayos, Fernando S, Baidoo, Leonard, Sparrow, Miles P, Bressler, Brian, Cheifetz, Adam S, Devlin, Shane M, Raffals, Laura E, Casteele, Niels Vande, Mould, Diane R, Colombel, Jean-Fred, Dubinsky, Marla, Sandborn, William J, Siegel, Corey A
Published in Clinical gastroenterology and hepatology (01.09.2016)
Published in Clinical gastroenterology and hepatology (01.09.2016)
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Journal Article
Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib
Hsyu, Poe-Hirr, Mould, Diane R, Abbas, Richat, Amantea, Michael
Published in DRUG METABOLISM AND PHARMACOKINETICS (2014)
Published in DRUG METABOLISM AND PHARMACOKINETICS (2014)
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Journal Article
Patient factors that increase infliximab clearance and shorten half-life in inflammatory bowel disease: a population pharmacokinetic study
Dotan, Iris, Ron, Yulia, Yanai, Henit, Becker, Stuart, Fishman, Sigal, Yahav, Lior, Ben Yehoyada, Merav, Mould, Diane R
Published in Inflammatory bowel diseases (01.12.2014)
Published in Inflammatory bowel diseases (01.12.2014)
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Journal Article
Dashboard-Driven Accelerated Infliximab Induction Dosing Increases Infliximab Durability and Reduces Immunogenicity
Dubinsky, Marla C, Mendiolaza, Michelle L, Phan, Becky L, Moran, Hunter R, Tse, Stacy S, Mould, Diane R
Published in Inflammatory bowel diseases (01.09.2022)
Published in Inflammatory bowel diseases (01.09.2022)
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Journal Article
Development and Implementation of Electronic Health Record-Integrated Model-Informed Clinical Decision Support Tools for the Precision Dosing of Drugs
Vinks, Alexander A, Peck, Richard W, Neely, Michael, Mould, Diane R
Published in Clinical pharmacology and therapeutics (01.01.2020)
Published in Clinical pharmacology and therapeutics (01.01.2020)
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Journal Article
Personalized Dosing of Infliximab in Patients With Inflammatory Bowel Disease Using a Bayesian Approach: A Next Step in Therapeutic Drug Monitoring
Desai, Devendra C, Dherai, Alpa J, Strik, Anne, Mould, Diane R
Published in Journal of clinical pharmacology (01.04.2023)
Published in Journal of clinical pharmacology (01.04.2023)
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Journal Article
Drug Development of Therapeutic Monoclonal Antibodies
Mould, Diane R., Meibohm, Bernd
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.08.2016)
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.08.2016)
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Journal Article