Translation of nanomedicines from lab to industrial scale synthesis: The case of squalene-adenosine nanoparticles
Dormont, Flavio, Rouquette, Marie, Mahatsekake, Clement, Gobeaux, Frédéric, Peramo, Arnaud, Brusini, Romain, Calet, Serge, Testard, Fabienne, Lepetre-Mouelhi, Sinda, Desmaële, Didier, Varna, Mariana, Couvreur, Patrick
Published in Journal of controlled release (10.08.2019)
Published in Journal of controlled release (10.08.2019)
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Journal Article
Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery
Sobot, Dunja, Mura, Simona, Yesylevskyy, Semen O., Dalbin, Laura, Cayre, Fanny, Bort, Guillaume, Mougin, Julie, Desmaële, Didier, Lepetre-Mouelhi, Sinda, Pieters, Grégory, Andreiuk, Bohdan, Klymchenko, Andrey S., Paul, Jean-Louis, Ramseyer, Christophe, Couvreur, Patrick
Published in Nature communications (30.05.2017)
Published in Nature communications (30.05.2017)
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Journal Article
A new nanomedicine of gemcitabine displays enhanced anticancer activity in sensitive and resistant leukemia types
Reddy, L. Harivardhan, Dubernet, Catherine, Mouelhi, Sinda Lepetre, Marque, Pierre Emmanuel, Desmaele, Didier, Couvreur, Patrick
Published in Journal of controlled release (04.12.2007)
Published in Journal of controlled release (04.12.2007)
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Journal Article
Self-Assembly of Squalene-Based Nucleolipids: Relating the Chemical Structure of the Bioconjugates to the Architecture of the Nanoparticles
Lepeltier, Elise, Bourgaux, Claudie, Rosilio, Véronique, Poupaert, Jacques H, Meneau, Florian, Zouhiri, Fatima, Lepêtre-Mouelhi, Sinda, Desmaële, Didier, Couvreur, Patrick
Published in Langmuir (03.12.2013)
Published in Langmuir (03.12.2013)
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Journal Article
Assessment of Squalene-Adenosine Nanoparticles in Two Rodent Models of Cardiac Ischemia-Reperfusion
Brusini, Romain, Tran, Natalie Lan Linh, Cailleau, Catherine, Domergue, Valérie, Nicolas, Valérie, Dormont, Flavio, Calet, Serge, Cajot, Caroline, Jouran, Albin, Lepetre-Mouelhi, Sinda, Laloy, Julie, Couvreur, Patrick, Varna, Mariana
Published in Pharmaceutics (21.06.2023)
Published in Pharmaceutics (21.06.2023)
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Journal Article
Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury
Gaudin, Alice, Yemisci, Müge, Eroglu, Hakan, Lepetre-Mouelhi, Sinda, Turkoglu, Omer Faruk, Dönmez-Demir, Buket, Caban, Seçil, Sargon, Mustafa Fevzi, Garcia-Argote, Sébastien, Pieters, Grégory, Loreau, Olivier, Rousseau, Bernard, Tagit, Oya, Hildebrandt, Niko, Le Dantec, Yannick, Mougin, Julie, Valetti, Sabrina, Chacun, Hélène, Nicolas, Valérie, Desmaële, Didier, Andrieux, Karine, Capan, Yilmaz, Dalkara, Turgay, Couvreur, Patrick
Published in Nature nanotechnology (24.11.2014)
Published in Nature nanotechnology (24.11.2014)
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Journal Article
Discovery of New Hexagonal Supramolecular Nanostructures Formed by Squalenoylation of an Anticancer Nucleoside Analogue
Couvreur, Patrick, Reddy, L. Harivardhan, Mangenot, Stéphanie, Poupaert, Jacques H., Desmaële, Didier, Lepêtre-Mouelhi, Sinda, Pili, Barbara, Bourgaux, Claudie, Amenitsch, H., Ollivon, Michel
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2008)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2008)
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Journal Article
Novel PEGylated Nanoassemblies Made of Self‐Assembled Squalenoyl Nucleoside Analogues
Bekkara‐Aounallah, Fawzia, Gref, Ruxandra, Othman, Mohammad, Reddy, L. Harivardhan, Pili, Barbara, Allain, Vanessa, Bourgaux, Claudie, Hillaireau, Hervé, Lepêtre‐Mouelhi, Sinda, Desmaële, Didier, Nicolas, Julien, Chafi, Nafa, Couvreur, Patrick
Published in Advanced functional materials (24.11.2008)
Published in Advanced functional materials (24.11.2008)
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Journal Article
Preclinical Toxicology (Subacute and Acute) and Efficacy of a New Squalenoyl Gemcitabine Anticancer Nanomedicine
Reddy, L Harivardhan, Marque, Pierre-Emmanuel, Dubernet, Catherine, Mouelhi, Sinda-Lepêtre, Desmaële, Didier, Couvreur, Patrick
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
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Journal Article
Squalenoyl Gemcitabine Monophosphate: Synthesis, Characterisation of Nanoassemblies and Biological Evaluation
Caron, Joachim, Lepeltier, Elise, Reddy, L. Harivardhan, Lepêtre-Mouelhi, Sinda, Wack, Séverine, Bourgaux, Claudie, Couvreur, Patrick, Desmaële, Didier
Published in European Journal of Organic Chemistry (01.05.2011)
Published in European Journal of Organic Chemistry (01.05.2011)
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Book Review
Journal Article
Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury
Gaudin, Alice, Yemisci, Müge, Eroglu, Hakan, Lepetre-Mouelhi, Sinda, Turkoglu, Omer Faruk, Dönmez-Demir, Buket, Caban, Seçil, Sargon, Mustafa Fevzi, Garcia-Argote, Sébastien, Pieters, Grégory, Loreau, Olivier, Rousseau, Bernard, Tagit, Oya, Hildebrandt, Niko, Le Dantec, Yannick, Mougin, Julie, Valetti, Sabrina, Chacun, Hélène, Nicolas, Valérie, Desmaële, Didier, Andrieux, Karine, Capan, Yilmaz, Dalkara, Turgay, Couvreur, Patrick
Published in Nature nanotechnology (2014)
Published in Nature nanotechnology (2014)
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Journal Article
Adenosine and lipids: A forced marriage or a love match?
Rouquette, Marie, Lepetre-Mouelhi, Sinda, Couvreur, Patrick
Published in Advanced drug delivery reviews (01.11.2019)
Published in Advanced drug delivery reviews (01.11.2019)
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Journal Article
Micro- and nanocarriers for pain alleviation
da Silva, Alexandre, Lepetre-Mouelhi, Sinda, Couvreur, Patrick
Published in Advanced drug delivery reviews (01.08.2022)
Published in Advanced drug delivery reviews (01.08.2022)
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Journal Article
Squalenoyl Nanomedicines as Potential Therapeutics
Couvreur, Patrick, Stella, Barbara, Reddy, L. Harivardhan, Hillaireau, Hervé, Dubernet, Catherine, Desmaële, Didier, Lepêtre-Mouelhi, Sinda, Rocco, Flavio, Dereuddre-Bosquet, Nathalie, Clayette, Pascal, Rosilio, Véronique, Marsaud, Véronique, Renoir, Jack-Michel, Cattel, Luigi
Published in Nano letters (01.11.2006)
Published in Nano letters (01.11.2006)
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Journal Article
Albumin-driven disassembly of lipidic nanoparticles: the specific case of the squalene-adenosine nanodrug
Gobeaux, Frédéric, Bizeau, Joëlle, Samson, Firmin, Marichal, Laurent, Grillo, Isabelle, Wien, Frank, Yesylevsky, Semen O, Ramseyer, Christophe, Rouquette, Marie, Lepêtre-Mouelhi, Sinda, Desmaële, Didier, Couvreur, Patrick, Guenoun, Patrick, Renault, Jean-Philippe, Testard, Fabienne
Published in Nanoscale (28.01.2020)
Published in Nanoscale (28.01.2020)
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Journal Article
A nanomedicine approach for the treatment of long-lasting pain
Hazam, Hadjer, Prades, Lucas, Cailleau, Catherine, Mougin, Julie, Feng, Jiao, Benhamou, Dan, Gobeaux, Frédéric, Hamdi, Leïla, Couvreur, Patrick, Sitbon, Philippe, Lepetre-Mouelhi, Sinda
Published in Journal of controlled release (01.09.2024)
Published in Journal of controlled release (01.09.2024)
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Journal Article
Leu-Enkephalin Lipid Prodrug Nanoparticles: Relationship between Nanoparticles’ Structure, Interaction with Bovine Serum Albumin, and Analgesic Activity
Lepetre-Mouelhi, Sinda, Gobeaux, Fréderic, Da Silva, Alexandre, Prades, Lucas, Feng, Jiao, Wien, Frank, Couvreur, Patrick, Testard, Fabienne
Published in Chemistry of materials (23.01.2024)
Published in Chemistry of materials (23.01.2024)
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