Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells
Kumar, Santhosh V, Er, Pei X, Lawlor, Kynan T, Motazedian, Ali, Scurr, Michelle, Ghobrial, Irene, Combes, Alexander N, Zappia, Luke, Oshlack, Alicia, Stanley, Edouard G, Little, Melissa H
Published in Development (Cambridge) (01.03.2019)
Published in Development (Cambridge) (01.03.2019)
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Journal Article
Efficient generation of human NOTCH ligand-expressing haemogenic endothelial cells as infrastructure for in vitro haematopoiesis and lymphopoiesis
Sun, Shicheng, Motazedian, Ali, Li, Jacky Y., Wijanarko, Kevin, Zhu, Joe Jiang, Tharmarajah, Kothila, Strumila, Kathleen A., Shkaruta, Anton, Nigos, L. Rayburn, Schiesser, Jacqueline V., Yu, Yi, Neeson, Paul J., Ng, Elizabeth S., Elefanty, Andrew G., Stanley, Edouard G.
Published in Nature communications (04.09.2024)
Published in Nature communications (04.09.2024)
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Journal Article
An Engineered N-Cadherin Substrate for Differentiation, Survival, and Selection of Pluripotent Stem Cell-Derived Neural Progenitors
Haque, Amranul, Adnan, Nihad, Motazedian, Ali, Akter, Farhima, Hossain, Sharif, Kutsuzawa, Koichi, Nag, Kakon, Kobatake, Eiry, Akaike, Toshihiro
Published in PloS one (05.08.2015)
Published in PloS one (05.08.2015)
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Journal Article
Human yolk sac-like haematopoiesis generates RUNX1- and GFI1/1B-dependent blood and SOX17-positive endothelium
Bruveris, Freya F, Ng, Elizabeth S, Leitoguinho, Ana Rita, Motazedian, Ali, Vlahos, Katerina, Sourris, Koula, Mayberry, Robyn, McDonald, Penelope, Azzola, Lisa, Davidson, Nadia M, Oshlack, Alicia, Stanley, Edouard G, Elefanty, Andrew G
Published in Development (Cambridge) (01.01.2020)
Published in Development (Cambridge) (01.01.2020)
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Journal Article
Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing
Hosseini Far, Hani, Patria, Yudha Nur, Motazedian, Ali, Elefanty, Andrew G., Stanley, Edouard G., Lamandé, Shireen R., Bateman, John F.
Published in Stem cell research (01.05.2019)
Published in Stem cell research (01.05.2019)
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Journal Article
The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line
Howden, Sara, Hosseini Far, Hani, Motazedian, Ali, Elefanty, Andrew G., Stanley, Edouard G., Lamandé, Shireen R., Bateman, John F.
Published in Stem cell research (01.07.2019)
Published in Stem cell research (01.07.2019)
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Journal Article
GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives
Kao, Tim, Labonne, Tanya, Niclis, Jonathan C., Chaurasia, Ritu, Lokmic, Zerina, Qian, Elizabeth, Bruveris, Freya F., Howden, Sara E., Motazedian, Ali, Schiesser, Jacqueline V., Costa, Magdaline, Sourris, Koula, Ng, Elizabeth, Anderson, David, Giudice, Antonietta, Farlie, Peter, Cheung, Michael, Lamande, Shireen R., Penington, Anthony J., Parish, Clare L., Thomson, Lachlan H., Rafii, Arash, Elliott, David A., Elefanty, Andrew G., Stanley, Edouard G.
Published in Current stem cell reports (13.09.2016)
Published in Current stem cell reports (13.09.2016)
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3135 – DECIPHERING THE CELL-INTRINSIC MECHANISMS CONTROLLING CELL FATE AND OUTPUT OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AT SINGLE CLONE RESOLUTION
Motazedian, Ali, Wainwright, Elanor, Lam, Enid, Fei, Liyang, Vassiliadis, Dane, Oshlack, Alicia, Dawson, Mark
Published in Experimental hematology (2023)
Published in Experimental hematology (2023)
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Journal Article
Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium
Bruveris, Freya F., Ng, Elizabeth S., Leitoguinho, Ana Rita, Motazedian, Ali, Vlahos, Katerina, Sourris, Koula, Mayberry, Robyn, McDonald, Penelope, Azzola, Lisa, Davidson, Nadia M., Oshlack, Alicia, Stanley, Edouard G., Elefanty, Andrew G.
Published in Development (Cambridge) (01.10.2021)
Published in Development (Cambridge) (01.10.2021)
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Journal Article
3042 – GROUP F SOX GENES DIRECT HUMAN EMBRYONIC VASCULAR AND HAEMATOPOIETIC DEVELOPMENT
Bruveris, Freya, Elefanty, Andrew, Leitoguinho, Ana Rita, Motazedian, Ali, Ng, Elizabeth, Sourris, Koula, Stanley, Edouard, Vlahos, Katerina
Published in Experimental hematology (2022)
Published in Experimental hematology (2022)
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Journal Article
Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids
Motazedian, Ali, Bruveris, Freya F., Kumar, Santhosh V., Schiesser, Jacqueline V., Chen, Tyrone, Ng, Elizabeth S., Chidgey, Ann P., Wells, Christine A., Elefanty, Andrew G., Stanley, Edouard G.
Published in Nature cell biology (01.01.2020)
Published in Nature cell biology (01.01.2020)
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Journal Article
3005 – GROUP F SOX GENES CONTROL HUMAN EMBRYONIC VASCULAR PATTERNING VIA NOTCH SIGNALING
Bruveris, Freya, Elefanty, Andrew, Leitoguinho, Ana Rita, Motazedian, Ali, Ng, Elizabeth, Sourris, Koula, Stanley, Ed, Vlahos, Katerina
Published in Experimental hematology (01.08.2021)
Published in Experimental hematology (01.08.2021)
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Journal Article
Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells
Ng, Elizabeth S, Sarila, Gulcan, Li, Jacky Y, Edirisinghe, Hasindu S, Saxena, Ritika, Sun, Shicheng, Bruveris, Freya F, Labonne, Tanya, Sleebs, Nerida, Maytum, Alexander, Yow, Raymond Y, Inguanti, Chantelle, Motazedian, Ali, Calvanese, Vincenzo, Capellera-Garcia, Sandra, Ma, Feiyang, Nim, Hieu T, Ramialison, Mirana, Bonifer, Constanze, Mikkola, Hanna K A, Stanley, Edouard G, Elefanty, Andrew G
Published in Nature biotechnology (02.09.2024)
Published in Nature biotechnology (02.09.2024)
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Journal Article
Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes
Joshi, Kriti, Elso, Colleen, Motazedian, Ali, Labonne, Tanya, Schiesser, Jacqueline V., Cameron, Fergus, Mannering, Stuart I., Elefanty, Andrew G., Stanley, Edouard G.
Published in Diabetologia (01.12.2019)
Published in Diabetologia (01.12.2019)
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Journal Article
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
Guirguis, Andrew A., Ofir-Rosenfeld, Yaara, Knezevic, Kathy, Blackaby, Wesley, Hardick, David, Chan, Yih-Chih, Motazedian, Ali, Gillespie, Andrea, Vassiliadis, Dane, Lam, Enid Y.N., Tran, Kevin, Andrews, Byron, Harbour, Michael E., Vasiliauskaite, Lina, Saunders, Claire J., Tsagkogeorga, Georgia, Azevedo, Aleksandra, Obacz, Joanna, Pilka, Ewa S., Carkill, Marie, MacPherson, Laura, Wainwright, Elanor N., Liddicoat, Brian, Blyth, Benjamin J., Albertella, Mark R., Rausch, Oliver, Dawson, Mark A.
Published in Cancer discovery (05.10.2023)
Published in Cancer discovery (05.10.2023)
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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
Chan, Kah Lok, Gomez, Juliana, Cardinez, Chelisa, Kumari, Nishi, Sparbier, Christina E., Lam, Enid Y.N., Yeung, Miriam M., Garciaz, Sylvain, Kuzich, James A., Ong, Doen Ming, Brown, Fiona C., Chan, Yih-Chih, Vassiliadis, Dane, Wainwright, Elanor N., Motazedian, Ali, Gillespie, Andrea, Fennell, Katie A., Lai, Junyun, House, Imran G., Macpherson, Laura, Ang, Ching-Seng, Dawson, Sarah-Jane, Beavis, Paul A., Wei, Andrew H., Burr, Marian L., Dawson, Mark A.
Published in Cancer cell (10.10.2022)
Published in Cancer cell (10.10.2022)
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Journal Article
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes
Sparbier, Christina E., Gillespie, Andrea, Gomez, Juliana, Kumari, Nishi, Motazedian, Ali, Chan, Kah Lok, Bell, Charles C., Gilan, Omer, Chan, Yih-Chih, Popp, Sarah, Gough, Daniel J., Eckersley-Maslin, Melanie A., Dawson, Sarah-Jane, Lehner, Paul J., Sutherland, Kate D., Ernst, Patricia, McGeehan, Gerard M., Lam, Enid Y. N., Burr, Marian L., Dawson, Mark A.
Published in Nature cell biology (01.02.2023)
Published in Nature cell biology (01.02.2023)
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