Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor
ABDI, Muna H, BESWICK, Paul J, LEJEUNE, Clarisse L, LIVERMORE, David G, MEDHURST, Stephen J, MICHEL, Anton D, MOSES, Andrew P, PAGE, Lee, PATEL, Sadhana, ROMAN, Shilina A, SENGER, Stefan, SLINGSBY, Brian, BILLINTON, Andy, STEADMAN, Jon G. A, STEVENS, Alexander J, WALTER, Daryl S, CHAMBERS, Laura J, CHARLTON, Andrew, COLLINS, Sue D, COLLIS, Katharine L, DEAN, David K, FONFRIA, Elena, GLEAVE, Robert J
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
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Journal Article
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X(7) receptor
Abberley, Lee, Bebius, Aude, Beswick, Paul J, Billinton, Andy, Collis, Katharine L, Dean, David K, Fonfria, Elena, Gleave, Robert J, Medhurst, Stephen J, Michel, Anton D, Moses, Andrew P, Patel, Sadhana, Roman, Shilina A, Scoccitti, Tiziana, Smith, Beverley, Steadman, Jon G A, Walter, Daryl S
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Journal Article
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X7 receptor
Abberley, Lee, Bebius, Aude, Beswick, Paul J., Billinton, Andy, Collis, Katharine L., Dean, David K., Fonfria, Elena, Gleave, Robert J., Medhurst, Stephen J., Michel, Anton D., Moses, Andrew P., Patel, Sadhana, Roman, Shilina A., Scoccitti, Tiziana, Smith, Beverley, Steadman, Jon G.A., Walter, Daryl S.
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Journal Article
Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor
Beswick, Paul J, Billinton, Andy, Chambers, Laura J, Dean, David K, Fonfria, Elena, Gleave, Robert J, Medhurst, Stephen J, Michel, Anton D, Moses, Andrew P, Patel, Sadhana, Roman, Shilina A, Roomans, Sue, Senger, Stefan, Stevens, Alexander J, Walter, Daryl S
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
CHAMBERS, Laura J, STEVENS, Alexander J, THEOBALD, Pam J, BESWICK, Paul J, GLEAVE, Robert J, ROMAN, Shilina A, SENGER, Stefan, MOSES, Andrew P, MICHEL, Anton D, WALTER, Daryl S, DAVIES, David J, LIVERMORE, David G, FONFRIA, Elena, DEMONT, Emmanuel H, VIMAL, Mythily
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
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Journal Article
Structure–activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
Beswick, Paul J., Billinton, Andy, Chambers, Laura J., Dean, David K., Fonfria, Elena, Gleave, Robert J., Medhurst, Stephen J., Michel, Anton D., Moses, Andrew P., Patel, Sadhana, Roman, Shilina A., Roomans, Sue, Senger, Stefan, Stevens, Alexander J., Walter, Daryl S.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X sub(7) receptor
Beswick, Paul J, Billinton, Andy, Chambers, Laura J, Dean, David K, Fonfria, Elena, Gleave, Robert J, Medhurst, Stephen J, Michel, Anton D, Moses, Andrew P, Patel, Sadhana, Roman, Shilina A, Roomans, Sue, Senger, Stefan, Stevens, Alexander J, Walter, Daryl S
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Get full text
Journal Article
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X sub(7) receptor
Abberley, Lee, Bebius, Aude, Beswick, Paul J, Billinton, Andy, Collis, Katharine L, Dean, David K, Fonfria, Elena, Gleave, Robert J, Medhurst, Stephen J, Michel, Anton D, Moses, Andrew P, Patel, Sadhana, Roman, Shilina A, Scoccitti, Tiziana, Smith, Beverley, Steadman, Jon GA, Walter, Daryl S
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Get full text
Journal Article
Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X sub(7) receptor
Chambers, Laura J, Stevens, Alexander J, Moses, Andrew P, Michel, Anton D, Walter, Daryl S, Davies, David J, Livermore, David G, Fonfria, Elena, Demont, Emmanuel H, Vimal, Mythily, Theobald, Pam J, Beswick, Paul J, Gleave, Robert J, Roman, Shilina A, Senger, Stefan
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
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Journal Article
Discovery and structure–activity relationships of a series of pyroglutamic acid amide antagonists of the P2X 7 receptor
Abdi, Muna H., Beswick, Paul J., Billinton, Andy, Chambers, Laura J., Charlton, Andrew, Collins, Sue D., Collis, Katharine L., Dean, David K., Fonfria, Elena, Gleave, Robert J., Lejeune, Clarisse L., Livermore, David G., Medhurst, Stephen J., Michel, Anton D., Moses, Andrew P., Page, Lee, Patel, Sadhana, Roman, Shilina A., Senger, Stefan, Slingsby, Brian, Steadman, Jon G.A., Stevens, Alexander J., Walter, Daryl S.
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
Get full text
Journal Article
Synthesis and structure–activity relationships of a series of (1 H-pyrazol-4-yl)acetamide antagonists of the P2X 7 receptor
Chambers, Laura J., Stevens, Alexander J., Moses, Andrew P., Michel, Anton D., Walter, Daryl S., Davies, David J., Livermore, David G., Fonfria, Elena, Demont, Emmanuel H., Vimal, Mythily, Theobald, Pam J., Beswick, Paul J., Gleave, Robert J., Roman, Shilina A., Senger, Stefan
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
Get full text
Journal Article