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Prasugrel 5 mg in the Very Elderly Attenuates Platelet Inhibition But Maintains Noninferiority to Prasugrel 10 mg in Nonelderly Patients
Erlinge, David, Gurbel, Paul A., James, Stefan, Lindahl, Tomas L., Svensson, Peter, Ten Berg, Jurrien M., Foley, David P., Wagner, Henrik, Brown, Patricia B., Luo, Junxiang, Zhou, Chunmei, Moser, Brian A., Jakubowski, Joseph A., Small, David S., Winters, Kenneth J., Angiolillo, Dominick J.
Published in Journal of the American College of Cardiology (13.08.2013)
Published in Journal of the American College of Cardiology (13.08.2013)
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Higher body weight patients on clopidogrel maintenance therapy have lower active metabolite concentrations, lower levels of platelet inhibition, and higher rates of poor responders than low body weight patients
Wagner, Henrik, Angiolillo, Dominick J., ten Berg, Jurrien M., Bergmeijer, Thomas O., Jakubowski, Joseph A., Small, David S., Moser, Brian A., Zhou, Chunmei, Brown, Patricia, James, Stefan, Winters, Kenneth J., Erlinge, David
Published in Journal of thrombosis and thrombolysis (2014)
Published in Journal of thrombosis and thrombolysis (2014)
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Impaired Responsiveness to the Platelet P2Y12 Receptor Antagonist Clopidogrel in Patients With Type 2 Diabetes and Coronary Artery Disease
Angiolillo, Dominick J., Jakubowski, Joseph A., Ferreiro, José Luis, Tello-Montoliu, Antonio, Rollini, Fabiana, Franchi, Francesco, Ueno, Masafumi, Darlington, Andrew, Desai, Bhaloo, Moser, Brian A., Sugidachi, Atsuhiro, Guzman, Luis A., Bass, Theodore A.
Published in Journal of the American College of Cardiology (09.09.2014)
Published in Journal of the American College of Cardiology (09.09.2014)
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Addition of ramucirumab or merestinib to standard first-line chemotherapy for locally advanced or metastatic biliary tract cancer: a randomised, double-blind, multicentre, phase 2 study
Valle, Juan W, Vogel, Arndt, Denlinger, Crystal S, He, Aiwu Ruth, Bai, Li-Yuan, Orlova, Rashida, Van Cutsem, Eric, Adeva, Jorge, Chen, Li-Tzong, Obermannova, Radka, Ettrich, Thomas J, Chen, Jen-Shi, Wasan, Harpreet, Girvan, Allicia C, Zhang, Wei, Liu, Jiangang, Tang, Chunlao, Ebert, Philip J, Aggarwal, Amit, McNeely, Samuel C, Moser, Brian A, Oliveira, Joana M, Carlesi, Roberto, Walgren, Richard A, Oh, Do-Youn
Published in The lancet oncology (01.10.2021)
Published in The lancet oncology (01.10.2021)
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A Phase Ib/II Study of Ramucirumab in Combination with Emibetuzumab in Patients with Advanced Cancer
Harding, James J., Zhu, Andrew X., Bauer, Todd M., Choueiri, Toni K., Drilon, Alexander, Voss, Martin H., Fuchs, Charles S., Abou-Alfa, Ghassan K., Wijayawardana, Sameera R., Wang, Xuejing Aimee, Moser, Brian A., Uruñuela, Arantxa, Wacheck, Volker, Bendell, Johanna C.
Published in Clinical cancer research (01.09.2019)
Published in Clinical cancer research (01.09.2019)
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Assessment of immunogenicity from galcanezumab phase 3 trials in patients with episodic or chronic migraine
Martinez, James M, Hindiyeh, Nada, Anglin, Greg, Kalidas, Kavita, Hodsdon, Michael E, Kielbasa, William, Moser, Brian A, Pearlman, Eric M, Garces, Sandra
Published in Cephalalgia (01.08.2020)
Published in Cephalalgia (01.08.2020)
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Prasugrel 5 mg in the Very Elderly Attenuates Platelet Inhibition But Maintains Noninferiority to Prasugrel 10 mg in Nonelderly Patients: The GENERATIONS Trial, A Pharmacodynamic and Pharmacokinetic Study in Stable Coronary Artery Disease Patients
ERLINGE, David, GURBEL, Paul A, CHUNMEI ZHOU, MOSER, Brian A, JAKUBOWSKI, Joseph A, SMALL, David S, WINTERS, Kenneth J, ANGIOLILLO, Dominick J, JAMES, Stefan, LINDAHL, Tomas L, SVENSSON, Peter, TEN BERG, Jurrien M, FOLEY, David P, WAGNER, Henrik, BROWN, Patricia B, JUNXIANG LUO
Published in Journal of the American College of Cardiology (13.08.2013)
Published in Journal of the American College of Cardiology (13.08.2013)
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A first-in-human phase I trial of LY2780301, a dual p70 S6 kinase and Akt Inhibitor, in patients with advanced or metastatic cancer
Azaro, Analia, Rodon, Jordi, Calles, Antonio, Braña, Irene, Hidalgo, Manuel, Lopez-Casas, Pedro P., Munoz, Manuel, Westwood, Paul, Miller, Joel, Moser, Brian A., Ohnmacht, Ute, Bumgardner, William, Benhadji, Karim A., Calvo, Emiliano
Published in Investigational new drugs (01.06.2015)
Published in Investigational new drugs (01.06.2015)
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The influence of body size on the pharmacodynamic and pharmacokinetic response to clopidogrel and prasugrel: A retrospective analysis of the FEATHER study
Jakubowski, Joseph A., Angiolillo, Dominick J., Zhou, Chunmei, Small, David S., Moser, Brian A., ten Berg, Jurrien M., Brown, Patricia B., James, Stefan, Winters, Kenneth J., Erlinge, David
Published in Thrombosis research (01.09.2014)
Published in Thrombosis research (01.09.2014)
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The effect of CYP2C19 gene polymorphisms on the pharmacokinetics and pharmacodynamics of prasugrel 5-mg, prasugrel 10-mg and clopidogrel 75-mg in patients with coronary artery disease
Gurbel, P A, Bergmeijer, T O, Tantry, U S, ten Berg, J M, Angiolillo, D J, James, S, Lindahl, T L, Svensson, P, Jakubowski, J A, Brown, P B, Duvvuru, S, Sundseth, S, Walker, J R, Small, D, Moser, B A, Winters, K J, Erlinge, D
Published in Thrombosis and haemostasis (2014)
Published in Thrombosis and haemostasis (2014)
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Clopidogrel metaboliser status based on point-of-care CYP2C19 genetic testing in patients with coronary artery disease
Erlinge, David, James, Stefan, Duvvuru, Suman, Jakubowski, Joseph A, Wagner, Henrik, Varenhorst, Christoph, Tantry, Udaya S, Brown, Patricia B, Small, David, Moser, Brian A, Sundseth, Scott S, Walker, Joseph R, Winters, Kenneth J, Gurbel, Paul A
Published in Thrombosis and haemostasis (2014)
Published in Thrombosis and haemostasis (2014)
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Prasugrel in children with sickle cell disease: pharmacokinetic and pharmacodynamic data from an open-label, adaptive-design, dose-ranging study
Styles, Lori, Heiselman, Darell, Heath, Lori E, Moser, Brian A, Small, David S, Jakubowski, Joseph A, Zhou, Chunmei, Redding-Lallinger, Rupa, Heeney, Matthew M, Quinn, Charles T, Rana, Sohail R, Kanter, Julie, Winters, Kenneth J
Published in Journal of pediatric hematology/oncology (01.01.2015)
Published in Journal of pediatric hematology/oncology (01.01.2015)
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Impaired Responsiveness to the Platelet P2Y12Receptor Antagonist Clopidogrel in Patients With Type 2 Diabetes and Coronary Artery Disease
Angiolillo, Dominick J, Jakubowski, Joseph A, Ferreiro, José Luis, Tello-Montoliu, Antonio, Rollini, Fabiana, Franchi, Francesco, Ueno, Masafumi, Darlington, Andrew, Desai, Bhaloo, Moser, Brian A, Sugidachi, Atsuhiro, Guzman, Luis A, Bass, Theodore A
Published in Journal of the American College of Cardiology (09.09.2014)
Published in Journal of the American College of Cardiology (09.09.2014)
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Prasugrel in Children with Sickle Cell Disease: Pharmacokinetic and Pharmacodynamic Characteristics from an Open-Label, Adaptive-Design, Dose-Ranging Study
Styles, Lori, Jakubowski, Joseph A., Heiselman, Darell E., Heath, Lori E., Zhou, Chunmei, Quinn, Charles T., Heeney, Matthew M., Redding-Lallinger, Rupa, Small, David S., Moser, Brian A., Winters, Kenneth J.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Impaired Responsiveness to the Platelet P2Y 12 Receptor Antagonist Clopidogrel in Patients With Type 2 Diabetes and Coronary Artery Disease
Angiolillo, Dominick J., MD, PhD, Jakubowski, Joseph A., PhD, Ferreiro, José Luis, MD, Tello-Montoliu, Antonio, MD, PhD, Rollini, Fabiana, MD, Franchi, Francesco, MD, Ueno, Masafumi, MD, Darlington, Andrew, MD, Desai, Bhaloo, PhD, Moser, Brian A., MS, Sugidachi, Atsuhiro, PhD, Guzman, Luis A., MD, Bass, Theodore A., MD
Published in Journal of the American College of Cardiology (2014)
Published in Journal of the American College of Cardiology (2014)
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Prasugrel 5-mg in the very elderly attenuates platelet inhibition but maintains non-inferiority to prasugrel 10-mg in non-elderly patients: The GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients
Erlinge, David, Gurbel, Paul A, James, Stefan, Lindahl, Tomas L, Svensson, Peter, Ten Berg, Jurrien M, Foley, David P, Wagner, Henrik, Brown, Patricia B, Luo, Junxiang, Zhou, Chunmei, Moser, Brian A, Jakubowski, Joseph A, Small, David S, Winters, Kenneth J, Angiolillo, Dominick J
Published in Journal of the American College of Cardiology (2013)
Published in Journal of the American College of Cardiology (2013)
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Abstract 1439: Cytochrome P450 Genetic Variants Predict Cardiovascular Outcomes following Treatment with Clopidogrel but not with Prasugrel
Mega, Jessica L, Shen, Lei, Wiviott, Stephen D, Walker, Joseph R, Hockett, Richard D, Brandt, John T, Moser, Brian A, Macias, William, Antman, Elliott M, Close, Sandra L, Lilly, Eli, Sabatine, Marc S
Published in Circulation (New York, N.Y.) (28.10.2008)
Published in Circulation (New York, N.Y.) (28.10.2008)
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