Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study
Papa, Sophie, Adami, Antonella, Metoudi, Michael, Beatson, Richard, George, Molly Sarah, Achkova, Daniela, Williams, Evangelia, Arif, Sefina, Reid, Fiona, Elstad, Maria, Beckley-Hoelscher, Nicholas, Douri, Abdel, Delord, Marc, Lyne, Mike, Shivapatham, Dharshene, Fisher, Christopher, Hope, Andrew, Gooljar, Sakina, Mitra, Arindam, Gomm, Linda, Morton, Cienne, Henley-Smith, Rhonda, Thavaraj, Selvam, Santambrogio, Alice, Andoniadou, Cynthia, Allen, Sarah, Gibson, Victoria, Cook, Gary J R, Parente-Pereira, Ana C, Davies, David M, Farzaneh, Farzin, Schurich, Anna, Guerrero-Urbano, Teresa, Jeannon, Jean-Pierre, Spicer, James, Maher, John
Published in Journal for immunotherapy of cancer (01.06.2023)
Published in Journal for immunotherapy of cancer (01.06.2023)
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Journal Article
Revitalising cancer trials post-pandemic: time for reform
Morton, Cienne, Sullivan, Richard, Sarker, Debashis, Posner, John, Spicer, James
Published in British journal of cancer (12.04.2023)
Published in British journal of cancer (12.04.2023)
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Journal Article
Next-generation sequencing and molecular therapy
Morton, Cienne, Sarker, Debashis, Ross, Paul
Published in Clinical medicine (London, England) (01.01.2023)
Published in Clinical medicine (London, England) (01.01.2023)
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Journal Article
75 Real world toxicity data for the use of ipilimumab plus nivolumab in malignant mesothelioma
Harriet, McGrath, Anam, Kaiser, Morton, Cienne, Gennatas, Spyridon, Ghosh, Sharmistha, Karapanagiotou, Eleni, Georgiou, Alexandras, Spicer, James
Published in Lung cancer (Amsterdam, Netherlands) (01.04.2024)
Published in Lung cancer (Amsterdam, Netherlands) (01.04.2024)
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Journal Article
Efficacy and safety of dendrimer-enhanced (DEP) cabazitaxel (DEP CTX) in patients with advanced solid cancers in a phase 1/2 trial (P1/2)
Spicer, James F., Pinato, David James, Forster, Martin, Joshua, Anthony M., Korolewicz, James, Aboud, Karam, Morton, Cienne, Liu, Jia (Jenny), Cosman, Rasha, Main, Nicola Jane, Le Meur, Julia, Paull, Jeremy, Edmondson, Stephanie Ruth, Jones, Robert Hugh
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
Dendrimer-enhanced (DEP) SN38 (DEP irinotecan) in patients (pts) with advanced solid tumors: A phase 1/2 trial
Liu, Jia (Jenny), Minchom, Anna Rachel, Greystoke, Alastair, Evans, T.R. Jeffry, Sarker, Debashis, Joshua, Anthony M., Morton, Cienne, Aktas, Burak Y, Cosman, Rasha, Chwialkowska, Dominika, Paull, Jeremy, Main, Nicola Jane, Jean-Francois, Bernadette Marie, Le Meur, Julia, Edmondson, Stephanie Ruth, Cook, Natalie
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
Evaluation of an automated artificial intelligence (AI)/ natural language processing (NLP) engine to match patients (pts) with advanced solid cancers to biomarker-driven early phase (EP) clinical trials
Morton, Cienne, Ruta, Daniel, Stavraka, Chara, Anam, Kaiser, Spicer, James F., Regan, Aoife, Sengul, Siru, Cernile, George, Borecki, Yulia, Schwering, Taralyn, Rai, Harpreet, Brierley, Phil, Duroe, Oenone, Quarterman, Alan, Sarker, Debashis
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Phase I trial of the RAF/MEK clamp VS-6766 in combination with everolimus using an intermittent schedule with expansion in NSCLC across multiple KRAS variants
Minchom, Anna Rachel, Sanchez Perez, Vicky, Morton, Cienne, Manickavasagar, Thubeena, Nintos, George, Lai-Kwon, Julia Elizabeth, Guo, Christina, Tunariu, Nina, Parker, Tom, Prout, Toby, Parmar, Mona, Turner, Alison Joanne, Finneran, Laura, Hall, Emma, Pachter, Jonathan A., Denis, Louis J., Spicer, James F., Banerji, Udai
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer
Wu, Yin, Biswas, Dhruva, Usaite, Ieva, Angelova, Mihaela, Boeing, Stefan, Karasaki, Takahiro, Veeriah, Selvaraju, Czyzewska-Khan, Justyna, Morton, Cienne, Joseph, Magdalene, Hessey, Sonya, Reading, James, Georgiou, Andrew, Al-Bakir, Maise, McGranahan, Nicholas, Jamal-Hanjani, Mariam, Hackshaw, Allan, Quezada, Sergio A, Hayday, Adrian C, Swanton, Charles
Published in Nature cancer (01.06.2022)
Published in Nature cancer (01.06.2022)
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Journal Article
PD-1 defines a distinct, functional, tissue-adapted state in Vδ1 + T cells with implications for cancer immunotherapy
Davies, Daniel, Kamdar, Shraddha, Woolf, Richard, Zlatareva, Iva, Iannitto, Maria Luisa, Morton, Cienne, Haque, Yasmin, Martin, Hannah, Biswas, Dhruva, Ndagire, Susan, Munonyara, Martina, Gillett, Cheryl, O'Neill, Olga, Nussbaumer, Oliver, Hayday, Adrian, Wu, Yin
Published in Nature cancer (01.03.2024)
Published in Nature cancer (01.03.2024)
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Journal Article
Abstract CT094: Phase I dose-escalation study evaluating the safety and tolerability of ginisortamab (UCB6114), a first-in-class anti-gremlin-1 monoclonal antibody (mAb), as monotherapy in advanced solid tumors
Sarker, Debashis, Blagden, Sarah, Cook, Natalie, Evans, Thomas R., Plummer, Ruth, Angelakas, Angelos, Bashir, Saira, Badri, Salma El, Mavroeidis, Leonidas, Morton, Cienne, Muhith, Abdul (Moe), White, Mark, Dixon, Rupert, Garric, Elodie, Mann, Joanne, Matthews, Ivan, Banerji, Udai
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Journal Article
Abstract 3461: Preclinical and clinical evaluation of the RAF/MEK clamp avutometinib (VS-6766) in combination with the mTOR inhibitor everolimus for the treatment of KRAS mutated non-small cell lung cancer
Rodney, Simon, Stewart, Adam R., Perez, Victoria Sanchez, Morton, Cienne, Pickard, Lisa A., Shakouri, Taleen, Prout, Toby, Parmar, Mona, Turner, Alison J., Coma, Silvia, Pachter, Jonathan, Finneran, Laura, Hall, Emma, Spicer, James, Minchom, Anna, Banerji, Udai
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
719 Phase 1 study of the porcupine (PORCN) inhibitor RXC004 in combination with the PD-1 inhibitor nivolumab in patients with advanced solid tumors
Cook, Natalie, Blagden, Sarah, Lopez, Juanita, Sarker, Debashis, Greystoke, Alastair, Bashir, Saira, Skolariki, Aglaia, ElBadri, Salma, Morton, Cienne, OrtegoFranco, Ana, MohamedKhan, Shybi, Eagle, Catherine, Flanagan, Eimear, Goodwin, Louise, Phillips, Caroline, Robertson, Jane, Tilston, Craig, Timmis, Helen, Woodcock, Simon, Plummer, Ruth
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Abstract B039: A phase 1/2 study of dendrimer-enhanced (DEP) SN38 (SN38-SPL9111/DEP irinotecan) in patients with advanced solid tumours
Liu, Jia, Minchom, Anna R, Greystoke, Alastair, Evans, Thomas R J, Sarker, Debashis, Joshua, Anthony M, Morton, Cienne, Gaus, Aisha, Yau, Wing, Cosman, Rasha, Chwialkowska, Dominika, Paull, Jeremy R A, Jean-Francois, Bernadette M, Fairley, Jacinth K, Main, Nicola J, Edmondson, Stephanie R, Cook, Natalie
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
Next-generation sequencing and molecular therapy
Morton, Cienne, Sarker, Debashis, Ross, Paul
Published in Clinical medicine (London, England) (01.01.2023)
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Published in Clinical medicine (London, England) (01.01.2023)
Journal Article