KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
Mahadevan, Krishnan K., McAndrews, Kathleen M., LeBleu, Valerie S., Yang, Sujuan, Lyu, Hengyu, Li, Bingrui, Sockwell, Amari M., Kirtley, Michelle L., Morse, Sami J., Moreno Diaz, Barbara A., Kim, Michael P., Feng, Ningping, Lopez, Anastasia M., Guerrero, Paola A., Paradiso, Francesca, Sugimoto, Hikaru, Arian, Kent A., Ying, Haoqiang, Barekatain, Yasaman, Sthanam, Lakshmi Kavitha, Kelly, Patience J., Maitra, Anirban, Heffernan, Timothy P., Kalluri, Raghu
Published in Cancer cell (11.09.2023)
Published in Cancer cell (11.09.2023)
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Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity
Luo, Xin, McAndrews, Kathleen M., Arian, Kent A., Morse, Sami J., Boeker, Viktoria, Kumbhar, Shreyasee V., Hu, Yingying, Mahadevan, Krishnan K., Church, Kaira A., Chitta, Sriram, Ryujin, Nicolas T., Hensel, Janine, Dai, Jianli, Dowlatshahi, Dara P., Sugimoto, Hikaru, Kirtley, Michelle L., LeBleu, Valerie S., Shalapour, Shabnam, Simmons, Joe H., Kalluri, Raghu
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Published in Journal of controlled release (01.10.2024)
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508 Collagen Deposition in White Adipose Tissue (WAT) Correlates With Hepatic Fibrosis in Non-Alcoholic Fatty Liver Disease (NAFLD) as Quantified by Computer-Assisted Morphometry (CAM)
Karrar, Azza, Abdelatif, Dinan, Ali, Irfan, Shaikh, Tasneem, Fazel, Sofie, Mohamed, Tibyan, Morse, Sami J, Monge, Fanny, Otgonsuren, Munkhzul, Nayer, Zacharia, Alaparthi, Lakshmi P, Goodman, Zachary, Younossi, Zobair M
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2016)
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KRASG12D inhibition reprograms the tumor microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
Mahadevan, Krishnan K., McAndrews, Kathleen M., LeBleu, Valerie S., Yang, Sujuan, Lyu, Hengyu, Li, Bingrui, Sockwell, Amari M., Kirtley, Michelle L., Morse, Sami J., Diaz, Barbara A. Moreno, Kim, Michael P., Feng, Ningping, Lopez, Anastasia M., Guerrero, Paola A., Paradiso, Francesca, Sugimoto, Hikaru, Arian, Kent A., Ying, Haoqiang, Barekatain, Yasaman, Sthanam, Lakshmi Kavitha, Kelly, Patience J., Maitra, Anirban, Heffernan, Timothy P., Kalluri, Raghu
Published in Cancer cell (24.08.2023)
Published in Cancer cell (24.08.2023)
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Abstract B092: CDK8 and CXCL2 remodel the tumor microenvironment to contribute to KRASG12D small molecule inhibition resistance in pancreatic ductal adenocarcinoma
McAndrews, Kathleen M., Mahadevan, Krishnan K., Li, Bingrui, Sockwell, Amari M., Morse, Sami J., Kelly, Patience J., Kirtley, Michelle L., Conner, Meagan R., Patel, Sarah I., Khumbar, Shreyasee V., Arian, Kent A., Barekatain, Yasaman, Moreno Diaz, Barbara A., Lyu, Hengyu, Sugimoto, Hikaru, Sthanam, Lakshmi Kavitha, Sobhani, Navid, Paradiso, Francesca, Bernard, Vincent, Guerrero, Paola, Ying, Haoqiang, Maitra, Anirban, Heffernan, Timothy P., Kalluri, Raghu
Published in Cancer research (Chicago, Ill.) (16.01.2024)
Published in Cancer research (Chicago, Ill.) (16.01.2024)
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Journal Article
KRAS G12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8 + T cells
Mahadevan, Krishnan K, McAndrews, Kathleen M, LeBleu, Valerie S, Yang, Sujuan, Lyu, Hengyu, Li, Bingrui, Sockwell, Amari M, Kirtley, Michelle L, Morse, Sami J, Moreno Diaz, Barbara A, Kim, Michael P, Feng, Ningping, Lopez, Anastasia M, Guerrero, Paola A, Paradiso, Francesca, Sugimoto, Hikaru, Arian, Kent A, Ying, Haoqiang, Barekatain, Yasaman, Sthanam, Lakshmi Kavitha, Kelly, Patience J, Maitra, Anirban, Heffernan, Timothy P, Kalluri, Raghu
Published in Cancer cell (11.09.2023)
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Published in Cancer cell (11.09.2023)
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Oncogenic Kras G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 + T cells dependent manner
Mahadevan, Krishnan K, McAndrews, Kathleen M, LeBleu, Valerie S, Yang, Sujuan, Lyu, Hengyu, Li, Bingrui, Sockwell, Amari M, Kirtley, Michelle L, Morse, Sami J, Moreno Diaz, Barbara A, Kim, Michael P, Feng, Ningping, Lopez, Anastasia M, Guerrero, Paola A, Sugimoto, Hikaru, Arian, Kent A, Ying, Haoqiang, Barekatain, Yasaman, Kelly, Patience J, Maitra, Anirban, Heffernan, Timothy P, Kalluri, Raghu
Published in bioRxiv : the preprint server for biology (18.02.2023)
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Published in bioRxiv : the preprint server for biology (18.02.2023)
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