Inherited predisposition to malignant mesothelioma and overall survival following platinum chemotherapy
Hassan, Raffit, Morrow, Betsy, Thomas, Anish, Walsh, Tom, Lee, Ming K., Gulsuner, Suleyman, Gadiraju, Meghana, Panou, Vasiliki, Gao, Shaojian, Mian, Idrees, Khan, Javed, Raffeld, Mark, Patel, Snehal, Xi, Liqiang, Wei, Jun S., Hesdorffer, Mary, Zhang, Jingli, Calzone, Kathleen, Desai, Arpita, Padiernos, Emerson, Alewine, Christine, Schrump, David S., Steinberg, Seth M., Kindler, Hedy L., King, Mary-Claire, Churpek, Jane E.
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2019)
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Journal Article
Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial
Lopez-Chavez, Ariel, Thomas, Anish, Rajan, Arun, Raffeld, Mark, Morrow, Betsy, Kelly, Ronan, Carter, Corey Allan, Guha, Udayan, Killian, Keith, Lau, Christopher C, Abdullaev, Zied, Xi, Liqiang, Pack, Svetlana, Meltzer, Paul S, Corless, Christopher L, Sandler, Alan, Beadling, Carol, Warrick, Andrea, Liewehr, David J, Steinberg, Seth M, Berman, Arlene, Doyle, Austin, Szabo, Eva, Wang, Yisong, Giaccone, Giuseppe
Published in Journal of clinical oncology (20.03.2015)
Published in Journal of clinical oncology (20.03.2015)
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Journal Article
Mutations of epigenetic regulatory genes are common in thymic carcinomas
Wang, Yisong, Thomas, Anish, Lau, Christopher, Rajan, Arun, Zhu, Yuelin, Killian, J Keith, Petrini, Iacopo, Pham, Trung, Morrow, Betsy, Zhong, Xiaogang, Meltzer, Paul S, Giaccone, Giuseppe
Published in Scientific reports (08.12.2014)
Published in Scientific reports (08.12.2014)
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Journal Article
Tumor-Derived GM-CSF Promotes Granulocyte Immunosuppression in Mesothelioma Patients
Khanna, Swati, Graef, Suzanne, Mussai, Francis, Thomas, Anish, Wali, Neha, Yenidunya, Bahar Guliz, Yuan, Constance, Morrow, Betsy, Zhang, Jingli, Korangy, Firouzeh, Greten, Tim F, Steinberg, Seth M, Stetler-Stevenson, Maryalice, Middleton, Gary, De Santo, Carmela, Hassan, Raffit
Published in Clinical cancer research (15.06.2018)
Published in Clinical cancer research (15.06.2018)
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Journal Article
Phase 2 Study of Olaparib in Malignant Mesothelioma and Correlation of Efficacy With Germline or Somatic Mutations in BAP1 Gene
Ghafoor, Azam, Mian, Idrees, Wagner, Cathy, Mallory, Yvonne, Agra, Maria Garcia, Morrow, Betsy, Wei, Jun S., Khan, Javed, Thomas, Anish, Sengupta, Manjistha, Steinberg, Seth M., Hassan, Raffit
Published in JTO clinical and research reports (01.10.2021)
Published in JTO clinical and research reports (01.10.2021)
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Journal Article
Inherited predisposition to malignant mesothelioma (MM) due to mutations in DNA repair genes
Hassan, Raffit, Morrow, Betsy, Walsh, Tom, Lee, Ming K, Gao, James, Mian, Idrees, Khan, Javed, Raffeld, Mark, Patel, Snehal, Xi, Liqiang, Wei, Jun S., Schrump, David, Hesdorffer, Mary, Zhang, Jingli, Calzone, Kathy, Padiernos, Emerson, Alewine, Christine, Steinberg, Seth M., Thomas, Anish, King, Mary-Claire
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Malignant Mesothelioma Effusions Are Infiltrated by CD3+ T Cells Highly Expressing PD-L1 and the PD-L1+ Tumor Cells within These Effusions Are Susceptible to ADCC by the Anti–PD-L1 Antibody Avelumab
Khanna, Swati, Thomas, Anish, Abate-Daga, Daniel, Zhang, Jingli, Morrow, Betsy, Steinberg, Seth M., Orlandi, Augusto, Ferroni, Patrizia, Schlom, Jeffrey, Guadagni, Fiorella, Hassan, Raffit
Published in Journal of thoracic oncology (01.11.2016)
Published in Journal of thoracic oncology (01.11.2016)
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Journal Article
Sensitivity of Mesothelioma Cells to PARP Inhibitors Is Not Dependent on BAP1 but Is Enhanced by Temozolomide in Cells With High-Schlafen 11 and Low-O6-methylguanine-DNA Methyltransferase Expression
Rathkey, Daniel, Khanal, Manakamana, Murai, Junko, Zhang, Jingli, Sengupta, Manjistha, Jiang, Qun, Morrow, Betsy, Evans, Christine N., Chari, Raj, Fetsch, Patricia, Chung, Hye-Jung, Xi, Liqiang, Roth, Mark, Filie, Armando, Raffeld, Mark, Thomas, Anish, Pommier, Yves, Hassan, Raffit
Published in Journal of thoracic oncology (01.05.2020)
Published in Journal of thoracic oncology (01.05.2020)
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Journal Article
Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models
Jiang, Qun, Ghafoor, Azam, Mian, Idrees, Rathkey, Daniel, Thomas, Anish, Alewine, Christine, Sengupta, Manjistha, Ahlman, Mark A, Zhang, Jingli, Morrow, Betsy, Steinberg, Seth M, Pastan, Ira, Hassan, Raffit
Published in Science translational medicine (01.07.2020)
Published in Science translational medicine (01.07.2020)
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Journal Article
Anaplastic Lymphoma Kinase Gene Rearrangement in Children and Young Adults With Mesothelioma
Mian, Idrees, Abdullaev, Zied, Morrow, Betsy, Kaplan, Rosandra N., Gao, Shaojian, Miettinen, Markku, Schrump, David S., Zgonc, Valerie, Wei, Jun S., Khan, Javed, Pack, Svetlana, Hassan, Raffit
Published in Journal of thoracic oncology (01.03.2020)
Published in Journal of thoracic oncology (01.03.2020)
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Journal Article
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma
Bononi, Angela, Goto, Keisuke, Ak, Guntulu, Yoshikawa, Yoshie, Emi, Mitsuru, Pastorino, Sandra, Carparelli, Lorenzo, Ferro, Angelica, Nasu, Masaki, Kim, Jin-Hee, Suarez, Joelle S., Xu, Ronghui, Tanji, Mika, Takinishi, Yasutaka, Minaai, Michael, Novelli, Flavia, Pagano, Ian, Gaudino, Giovanni, Pass, Harvey I., Groden, Joanna, Grzymski, Joseph J., Metintas, Muzaffer, Akarsu, Muhittin, Morrow, Betsy, Hassan, Raffit, Yang, Haining, Carbone, Michele
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2020)
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Journal Article
A Pilot Study of Sirolimus in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in PTEN
Komiya, Takefumi, Blumenthal, Gideon M., DeChowdhury, Roopa, Fioravanti, Susan, Ballas, Marc S., Morris, John, Hornyak, Thomas J., Wank, Stephen, Hewitt, Stephen M., Morrow, Betsy, Memmott, Regan M., Rajan, Arun, Dennis, Phillip A.
Published in The oncologist (Dayton, Ohio) (01.12.2019)
Published in The oncologist (Dayton, Ohio) (01.12.2019)
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Journal Article
Phase II study of olaparib in malignant mesothelioma (MM) to correlate efficacy with germline and somatic mutations in DNA repair genes
Hassan, Raffit, Mian, Idrees, Wagner, Cathy, Mallory, Yvonne, Agra, Maria, Padiernos, Emerson, Sengupta, Manjistha, Morrow, Betsy, Wei, Jun S., Thomas, Anish, Steinberg, Seth M., Khan, Javed, Ghafoor, Azam
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Abstract 667: Genomic and transcriptomic profiling of malignant mesothelioma patients identifies gene signatures predictive of survival and response to immuno and chemotherapy
Nair, Nishanth Ulhas, Jiang, Qun, Wei, Jun S., Misra, Vikram A., Morrow, Betsy, Hermida, Leandro C., Lee, Joo Sang, Mian, Idrees, Zhang, Jingli, Sengupta, Manjistha, Khan, Javed, Ruppin, Eytan, Hassan, Raffit
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 3103: The reduced immunogenicity anti-mesothelin immunotoxin RG7787 in combination with nab-paclitaxel has significant anti-tumor efficacy against primary mesothelioma cell lines and patient derived mesothelioma tumor xenografts
Zhang, Jingli, Jiang, Qun, Alewine, Christine, Khanna, Swati, Morrow, Betsy, Thomas, Anish, Pastan, Ira, Hassan, Raffit
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Brief Report: Anaplastic lymphoma kinase (ALK) Gene Rearrangement in Children and Young Adults with Mesothelioma
Mian, Idrees, Abdullaev, Zied, Morrow, Betsy, Kaplan, Rosandra N., Gao, Shaojian, Mettienen, Markku, Schrump, David S., Zgonc, Valerie, Wei, Jun S., Khan, Javed, Pack, Svetlana, Hassan, Raffit
Published in Journal of thoracic oncology (26.11.2019)
Published in Journal of thoracic oncology (26.11.2019)
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Journal Article
Sensitivity of mesothelioma cells to PARP inhibitors is not dependent on BAP1 but is enhanced by temozolomide in cells with high-Schlafen 11and low-MGMT expression
Rathkey, Daniel, Khanal, Manakamana, Murai, Junko, Zhang, Jingli, Sengupta, Manjistha, Jiang, Qun, Morrow, Betsy, Evans, Christine N., Chari, Raj, Fetsch, Patricia, Chung, Hye-Jung, Xi, Liqiang, Roth, Mark, Filie, Armando, Raffeld, Mark, Thomas, Anish, Pommier, Yves, Hassan, Raffit
Published in Journal of thoracic oncology (28.01.2020)
Published in Journal of thoracic oncology (28.01.2020)
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Journal Article
Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma
Nair, Nishanth Ulhas, Jiang, Qun, Wei, Jun Stephen, Misra, Vikram Alexander, Morrow, Betsy, Kesserwan, Chimene, Hermida, Leandro C., Lee, Joo Sang, Mian, Idrees, Zhang, Jingli, Lebensohn, Alexandra, Miettinen, Markku, Sengupta, Manjistha, Khan, Javed, Ruppin, Eytan, Hassan, Raffit
Published in Cell reports. Medicine (21.02.2023)
Published in Cell reports. Medicine (21.02.2023)
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Abstract 3247: Granulocytic MDSCs (CD11b+CD15+CD14-HLADR-) in peripheral blood of mesothelioma patients are elevated and suppress T cell proliferation and function via reactive oxygen species
Khanna, Swati, Mussai, Francis, Thomas, Anish, Middleton, Gary, Yuan, Constance, Morrow, Betsy, Zhang, Jingli, Pastan, Ira, Stetler-Stevenson, Maryalice, Hassan, Raffit
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors
Blumenthal, Gideon M, Gills, Joell J, Ballas, Marc S, Bernstein, Wendy B, Komiya, Takefumi, Dechowdhury, Roopa, Morrow, Betsy, Root, Hyejeong, Chun, Guinevere, Helsabeck, Cynthia, Steinberg, Seth M, LoPiccolo, Jaclyn, Kawabata, Shigeru, Gardner, Erin R, Figg, William D, Dennis, Phillip A
Published in Oncotarget (30.09.2014)
Published in Oncotarget (30.09.2014)
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