The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
Zahreddine, Hiba Ahmad, Culjkovic-Kraljacic, Biljana, Assouline, Sarit, Gendron, Patrick, Romeo, Andrea A., Morris, Stephen J., Cormack, Gregory, Jaquith, James B., Cerchietti, Leandro, Cocolakis, Eftihia, Amri, Abdellatif, Bergeron, Julie, Leber, Brian, Becker, Michael W., Pei, Shanshan, Jordan, Craig T., Miller, Wilson H., Borden, Katherine L. B.
Published in Nature (London) (03.07.2014)
Published in Nature (London) (03.07.2014)
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Phase I/II Trial of AEG35156 X-Linked Inhibitor of Apoptosis Protein Antisense Oligonucleotide Combined With Idarubicin and Cytarabine in Patients With Relapsed or Primary Refractory Acute Myeloid Leukemia
SCHIMMER, Aaron D, ESTEY, Elihu H, BRANDWEIN, Joseph, WEI XU, MAK, Duncan H, LACASSE, Eric, JACOB, Christine, MORRIS, Stephen J, JOLIVET, Jacques, ANDREEFF, Michael, BORTHAKUR, Gautam, CARTER, Bing Z, SCHILLER, Gary J, TALLMAN, Martin S, ALTMAN, Jessica K, KARP, Judith E, KASSIS, Jeannine, HEDLEY, David W
Published in Journal of clinical oncology (01.10.2009)
Published in Journal of clinical oncology (01.10.2009)
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Journal Article
Electric-Field Assisted Growth and Self-Assembly of Intrinsic Silicon Nanowires
Englander, Ongi, Christensen, Dane, Kim, Jongbaeg, Lin, Liwei, Morris, Stephen J. S
Published in Nano letters (01.04.2005)
Published in Nano letters (01.04.2005)
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Journal Article
Preclinical Characterization of AEG35156/GEM 640, a Second-Generation Antisense Oligonucleotide Targeting X-Linked Inhibitor of Apoptosis
LACASSE, Eric C, CHERTON-HORVAT, Gabriele G, AGRAWAL, Sudhir, GILLARD, John W, DURKIN, Jon P, HEWITT, Kimberley E, JEROME, Lori J, MORRIS, Stephen J, KANDIMALLA, Ekambar R, DONG YU, HUI WANG, WEI WANG, RUIWEN ZHANG
Published in Clinical cancer research (01.09.2006)
Published in Clinical cancer research (01.09.2006)
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Cytoprotective effects of IAPs revealed by a small molecule antagonist
Galbán, Stefanie, Hwang, Clara, Rumble, Julie M, Oetjen, Karolyn A, Wright, Casey W, Boudreault, Alain, Durkin, Jon, Gillard, John W, Jaquith, James B, Morris, Stephen J, Duckett, Colin S
Published in Biochemical journal (01.02.2009)
Published in Biochemical journal (01.02.2009)
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Journal Article
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
Gallo, David, Young, Jordan T. F., Fourtounis, Jimmy, Martino, Giovanni, Álvarez-Quilón, Alejandro, Bernier, Cynthia, Duffy, Nicole M., Papp, Robert, Roulston, Anne, Stocco, Rino, Szychowski, Janek, Veloso, Artur, Alam, Hunain, Baruah, Prasamit S., Fortin, Alexanne Bonneau, Bowlan, Julian, Chaudhary, Natasha, Desjardins, Jessica, Dietrich, Evelyne, Fournier, Sara, Fugère-Desjardins, Chloe, Goullet de Rugy, Theo, Leclaire, Marie-Eve, Liu, Bingcan, Bhaskaran, Vivek, Mamane, Yael, Melo, Henrique, Nicolas, Olivier, Singhania, Akul, Szilard, Rachel K., Tkáč, Ján, Yin, Shou Yun, Morris, Stephen J., Zinda, Michael, Marshall, C. Gary, Durocher, Daniel
Published in Nature (London) (28.04.2022)
Published in Nature (London) (28.04.2022)
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Journal Article
Differential Sorting of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal Neurons
Mowla, S. Javad, Pareek, Sangeeta, Farhadi, Hooman F, Petrecca, Kevin, Fawcett, James P, Seidah, Nabil G, Morris, Stephen J, Sossin, Wayne S, Murphy, Richard A
Published in The Journal of neuroscience (15.03.1999)
Published in The Journal of neuroscience (15.03.1999)
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Journal Article
cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination
Bertrand, Mathieu J.M., Milutinovic, Snezana, Dickson, Kathleen M., Ho, Wai Chi, Boudreault, Alain, Durkin, Jon, Gillard, John W., Jaquith, James B., Morris, Stephen J., Barker, Philip A.
Published in Molecular cell (20.06.2008)
Published in Molecular cell (20.06.2008)
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Journal Article
K252a and CEP1347 Are Neuroprotective Compounds That Inhibit Mixed-lineage Kinase-3 and Induce Activation of Akt and ERK
Roux, Philippe P., Dorval, Geneviève, Boudreau, Mathieu, Angers-Loustau, Alexandre, Morris, Stephen J., Makkerh, Joe, Barker, Philip A.
Published in The Journal of biological chemistry (20.12.2002)
Published in The Journal of biological chemistry (20.12.2002)
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Journal Article
Extremely low frequency electromagnetic field exposure promotes differentiation of pituitary corticotrope-derived AtT20 D16V cells
Lisi, Antonella, Ledda, Mario, Rosola, Emanuela, Pozzi, Deleana, Emilia, Enrico D′, Giuliani, Livio, Foletti, Alberto, Modesti, Andrea, Morris, Stephen J., Grimaldi, Settimio
Published in Bioelectromagnetics (01.12.2006)
Published in Bioelectromagnetics (01.12.2006)
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Journal Article
Differential desensitization of dopamine D2 receptor isoforms by protein kinase C : The importance of receptor phosphorylation and pseudosubstrate sites
MORRIS, Stephen J, ITZHAKI VAN-HAM, Irit, DAIGLE, Mireille, ROBILLARD, Liliane, SAJEDI, Naghmeh, ALBERT, Paul R
Published in European journal of pharmacology (22.12.2007)
Published in European journal of pharmacology (22.12.2007)
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Journal Article
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ
Bubenik, Monica, Mader, Pavel, Mochirian, Philippe, Vallée, Fréderic, Clark, Jillian, Truchon, Jean-François, Perryman, Alexander L., Pau, Victor, Kurinov, Igor, Zahn, Karl E., Leclaire, Marie-Eve, Papp, Robert, Mathieu, Marie-Claude, Hamel, Martine, Duffy, Nicole M., Godbout, Claude, Casas-Selves, Matias, Falgueyret, Jean-Pierre, Baruah, Prasamit S., Nicolas, Olivier, Stocco, Rino, Poirier, Hugo, Martino, Giovanni, Fortin, Alexanne Bonneau, Roulston, Anne, Chefson, Amandine, Dorich, Stéphane, St-Onge, Miguel, Patel, Purvish, Pellerin, Charles, Ciblat, Stéphane, Pinter, Thomas, Barabé, Francis, El Bakkouri, Majida, Parikh, Paranjay, Gervais, Christian, Sfeir, Agnel, Mamane, Yael, Morris, Stephen J., Black, W. Cameron, Sicheri, Frank, Gallant, Michel
Published in Journal of medicinal chemistry (13.10.2022)
Published in Journal of medicinal chemistry (13.10.2022)
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Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and Suicide
Lemonde, Sylvie, Turecki, Gustavo, Bakish, David, Du, Lisheng, Hrdina, Pavel D, Bown, Christopher D, Sequeira, Adolfo, Kushwaha, Neena, Morris, Stephen J, Basak, Ajoy, Ou, Xiao-Ming, Albert, Paul R
Published in The Journal of neuroscience (24.09.2003)
Published in The Journal of neuroscience (24.09.2003)
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Journal Article
XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34⁺38⁻ cells in a phase 1/2 study of patients with relapsed/refractory AML
Carter, Bing Z, Mak, Duncan H, Morris, Stephen J, Borthakur, Gautam, Estey, Elihu, Byrd, Anna L, Konopleva, Marina, Kantarjian, Hagop, Andreeff, Michael
Published in Apoptosis (London) (2011)
Published in Apoptosis (London) (2011)
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Journal Article
Biosynthesis and Post-translational Processing of the Precursor to Brain-derived Neurotrophic Factor
Mowla, S J, Farhadi, H F, Pareek, S, Atwal, J K, Morris, S J, Seidah, N G, Murphy, R A
Published in The Journal of biological chemistry (20.04.2001)
Published in The Journal of biological chemistry (20.04.2001)
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Journal Article
Deleted in Colorectal Cancer Binding Netrin-1 Mediates Cell Substrate Adhesion and Recruits Cdc42, Rac1, Pak1, and N-WASP into an Intracellular Signaling Complex That Promotes Growth Cone Expansion
Shekarabi, Masoud, Moore, Simon W, Tritsch, Nicolas X, Morris, Stephen J, Bouchard, Jean-Francois, Kennedy, Timothy E
Published in The Journal of neuroscience (23.03.2005)
Published in The Journal of neuroscience (23.03.2005)
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Journal Article
Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics
MCMANUS, Dan C, LEFEBVRE, Charles A, CHERTON-HORVAT, Gabriele, ST-JEAN, Martine, KANDIMALLA, Ekambar R, AGRAWAL, Sudhir, MORRIS, Stephen J, DURKIN, Jon P, LACASSE, Eric C
Published in Oncogene (21.10.2004)
Published in Oncogene (21.10.2004)
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Journal Article
X-linked Inhibitor of Apoptosis Regulates T Cell Effector Function
Zehntner, Simone P, Bourbonniere, Lyne, Moore, Craig S, Morris, Stephen J, Methot, Danielle, St. Jean, Martine, Lacasse, Eric, Hebb, Andrea L. O, Robertson, George S, Durkin, Jon, Gillard, John W, Owens, Trevor
Published in The Journal of immunology (1950) (01.12.2007)
Published in The Journal of immunology (1950) (01.12.2007)
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