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Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2017)
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Published in The Journal of biological chemistry (14.02.2014)
Published in The Journal of biological chemistry (14.02.2014)
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Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion
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Published in mBio (04.04.2017)
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Published in Nature chemical biology (01.04.2016)
Published in Nature chemical biology (01.04.2016)
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Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase
Tso, Shih-Chia, Qi, Xiangbing, Gui, Wen-Jun, Chuang, Jacinta L., Morlock, Lorraine K., Wallace, Amy L., Ahmed, Kamran, Laxman, Sunil, Campeau, Philippe M., Lee, Brendan H., Hutson, Susan M., Tu, Benjamin P., Williams, Noelle S., Tambar, Uttam K., Wynn, R. Max, Chuang, David T.
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2013)
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Discovery of a Neuroprotective Chemical, (S)‑N‑(3-(3,6-Dibromo‑9H‑carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(−)-P7C3-S243], with Improved Druglike Properties
Naidoo, Jacinth, De Jesus-Cortes, Hector, Huntington, Paula, Estill, Sandi, Morlock, Lorraine K, Starwalt, Ruth, Mangano, Thomas J, Williams, Noelle S, Pieper, Andrew A, Ready, Joseph M
Published in Journal of medicinal chemistry (08.05.2014)
Published in Journal of medicinal chemistry (08.05.2014)
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Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors
Tso, Shih-Chia, Lou, Mingliang, Wu, Cheng-Yang, Gui, Wen-Jun, Chuang, Jacinta L, Morlock, Lorraine K, Williams, Noelle S, Wynn, R. Max, Qi, Xiangbing, Chuang, David T
Published in Journal of medicinal chemistry (09.02.2017)
Published in Journal of medicinal chemistry (09.02.2017)
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Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase
Tso, Shih-Chia, Gui, Wen-Jun, Wu, Cheng-Yang, Chuang, Jacinta L., Qi, Xiangbing, Skvorak, Kristen J., Dorko, Kenneth, Wallace, Amy L., Morlock, Lorraine K., Lee, Brendan H., Hutson, Susan M., Strom, Stephen C., Williams, Noelle S., Tambar, Uttam K., Wynn, R.Max, Chuang, David T.
Published in The Journal of biological chemistry (25.07.2014)
Published in The Journal of biological chemistry (25.07.2014)
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Discovery of a Neuroprotective Chemical, (S)-N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxyp y ridin-2-amine [(-)-P7C3-S243], with Improved Druglike Properties
Naidoo, Jacinth, De Jesus-Cortes, Hector, Huntington, Paula, Estill, Sandi, Morlock, Lorraine K, Starwalt, Ruth, Mangano, Thomas J, Williams, Noelle S, Pieper, Andrew A, Ready, Joseph M
Published in Journal of medicinal chemistry (03.04.2014)
Published in Journal of medicinal chemistry (03.04.2014)
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Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain [alpha]-ketoacid dehydrogenase kinase
Tso, Shih-Chia, Qi, Xiangbing, Gui, Wen-Jun, Chuang, Jacinta L, Morlock, Lorraine K, Wallace, Amy L, Ahmed, Kamran, Laxman, Sunil, Campeau, Philippe M, Lee, Brendan H, Hutson, Susan M, Tu, Benjamin P, Williams, Noelle S, Tambar, Uttam K, Wynn, R Max, Chuang, David T
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2013)
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Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2013)
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