Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models
Suominen, Mari I, Fagerlund, Katja M, Rissanen, Jukka P, Konkol, Yvonne M, Morko, Jukka P, Peng, ZhiQi, Alhoniemi, Esa J, Laine, Salla K, Corey, Eva, Mumberg, Dominik, Ziegelbauer, Karl, Käkönen, Sanna-Maria, Halleen, Jussi M, Vessella, Robert L, Scholz, Arne
Published in Clinical cancer research (01.08.2017)
Published in Clinical cancer research (01.08.2017)
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Journal Article
Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio
Kiviranta, Riku, Morko, Jukka, Alatalo, Sari L., NicAmhlaoibh, Roisin, Risteli, Juha, Laitala-Leinonen, Tiina, Vuorio, Eero
Published in Bone (New York, N.Y.) (01.01.2005)
Published in Bone (New York, N.Y.) (01.01.2005)
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Journal Article
Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
Srivastava, Mrigank, Steinwede, Kathrin, Kiviranta, Riku, Morko, Jukka, Hoymann, Heinz-Gerd, Länger, Florian, Buhling, Frank, Welte, Tobias, Maus, Ulrich A
Published in Respiratory research (18.07.2008)
Published in Respiratory research (18.07.2008)
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Journal Article
Short-Term Changes in Serum PINP Predict Long-Term Changes in Trabecular Bone in the Rat Ovariectomy Model
Rissanen, Jukka P., Suominen, Mari I., Peng, Zhiqi, Morko, Jukka, Rasi, Simo, Risteli, Juha, Halleen, Jussi M.
Published in Calcified tissue international (01.02.2008)
Published in Calcified tissue international (01.02.2008)
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Journal Article
Novel 2,7-Diazaspiro[4,4]nonane Derivatives to Inhibit Mouse and Human Osteoclast Activities and Prevent Bone Loss in Ovariectomized Mice without Affecting Bone Formation
Mounier, Lucile, Morel, Anne, Ferrandez, Yann, Morko, Jukka, Vääräniemi, Jukka, Gilardone, Marine, Roche, Didier, Cherfils, Jacqueline, Blangy, Anne
Published in Journal of medicinal chemistry (25.11.2020)
Published in Journal of medicinal chemistry (25.11.2020)
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Journal Article
Differences in knee osteoarthritis between surgically and chemically induced rat models
Vääräniemi, Jukka, Morko, Jukka, Fagerlund, Katja M., Rissanen, Jukka P.
Published in Bone Reports (01.05.2022)
Published in Bone Reports (01.05.2022)
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Journal Article
Abstract 381: PI3K inhibitor BAY 1082439 and radium-223 dichloride decrease tumor burden and tumor-induced bone formation in an established bone metastatic prostate cancer model in mice
Suominen, Mari I., Morko, Jukka, Fagerlund, Katja M., Alhoniemi, Esa, Mumberg, Dominik, Ziegelbauer, Karl, Halleen, Jussi M., Scholz, Arne, Liu, Ningshu
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 3447: Radium-223 dichloride exhibits dual mode-of-action inhibiting both tumor and tumor-induced bone growth in two osteoblastic prostate cancer models
Suominen, Mari I., Fagerlund, Katja M., Rissanen, Jukka P., Konkol, Yvonne, Morko, Jukka, Peng, Zhiqi, Alhoniemi, Esa, Mumberg, Dominik, Ziegelbauer, Karl, Käkönen, Sanna-Maria, Halleen, Jussi M., Vessella, Robert L., Scholz, Arne
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Effects of Diet-Induced Obesity and Voluntary Wheel Running on Bone Properties in Young Male C57BL/6J Mice
Ma, Hongqiang, Torvinen, Sira, Silvennoinen, Mika, Rinnankoski-Tuikka, Rita, Kainulainen, Heikki, Morko, Jukka, Peng, Zhiqi, Kujala, Urho M., Rahkila, Paavo, Suominen, Harri
Published in Calcified tissue international (01.05.2010)
Published in Calcified tissue international (01.05.2010)
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Journal Article
ZP2307, a novel, cyclic PTH(1-17) analog that augments bone mass in ovariectomized rats
Neerup, Trine S.R, Stahlhut, Martin, Petersen, Jørgen S, Daugaard, Jens R, Jensen, Jens-Erik B, Peng, ZhiQi, Morko, Jukka, Thorkildsen, Christian
Published in Bone (New York, N.Y.) (01.06.2011)
Published in Bone (New York, N.Y.) (01.06.2011)
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Journal Article
Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro
Morko, Jukka, Kiviranta, Riku, Mulari, Mika T.K, Ivaska, Kaisa K, Väänänen, H. Kalervo, Vuorio, Eero, Laitala-Leinonen, Tiina
Published in Bone (New York, N.Y.) (01.04.2009)
Published in Bone (New York, N.Y.) (01.04.2009)
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Journal Article
Differential turnover of cortical and trabecular bone in transgenic mice overexpressing cathepsin K
Morko, Jukka, Kiviranta, Riku, Hurme, Sara, Rantakokko, Juho, Vuorio, Eero
Published in Bone (New York, N.Y.) (01.05.2005)
Published in Bone (New York, N.Y.) (01.05.2005)
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Journal Article
Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene
Savontaus, M, Rintala-Jämsä, M, Morko, J, Rönning, O, Metsäranta, M, Vuorio, E
Published in Orthodontics & craniofacial research (01.11.2004)
Published in Orthodontics & craniofacial research (01.11.2004)
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