Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma
Bischoff, Philip, Trinks, Alexandra, Obermayer, Benedikt, Pett, Jan Patrick, Wiederspahn, Jennifer, Uhlitz, Florian, Liang, Xizi, Lehmann, Annika, Jurmeister, Philipp, Elsner, Aron, Dziodzio, Tomasz, Rückert, Jens-Carsten, Neudecker, Jens, Falk, Christine, Beule, Dieter, Sers, Christine, Morkel, Markus, Horst, David, Blüthgen, Nils, Klauschen, Frederick
Published in Oncogene (16.12.2021)
Published in Oncogene (16.12.2021)
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Journal Article
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
Brandt, Raphael, Sell, Thomas, Lüthen, Mareen, Uhlitz, Florian, Klinger, Bertram, Riemer, Pamela, Giesecke-Thiel, Claudia, Schulze, Silvia, El-Shimy, Ismail Amr, Kunkel, Desiree, Fauler, Beatrix, Mielke, Thorsten, Mages, Norbert, Herrmann, Bernhard G., Sers, Christine, Blüthgen, Nils, Morkel, Markus
Published in Nature communications (02.07.2019)
Published in Nature communications (02.07.2019)
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Journal Article
Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Uhlitz, Florian, Bischoff, Philip, Peidli, Stefan, Sieber, Anja, Trinks, Alexandra, Lüthen, Mareen, Obermayer, Benedikt, Blanc, Eric, Ruchiy, Yana, Sell, Thomas, Mamlouk, Soulafa, Arsie, Roberto, Wei, Tzu‐Ting, Klotz‐Noack, Kathleen, Schwarz, Roland F, Sawitzki, Birgit, Kamphues, Carsten, Beule, Dieter, Landthaler, Markus, Sers, Christine, Horst, David, Blüthgen, Nils, Morkel, Markus
Published in EMBO molecular medicine (07.10.2021)
Published in EMBO molecular medicine (07.10.2021)
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Journal Article
Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis
Aguilar, Carmen, Pauzuolis, Mindaugas, Pompaiah, Malvika, Vafadarnejad, Ehsan, Arampatzi, Panagiota, Fischer, Mara, Narres, Dominik, Neyazi, Mastura, Kayisoglu, Özge, Sell, Thomas, Blüthgen, Nils, Morkel, Markus, Wiegering, Armin, Germer, Christoph-Thomas, Kircher, Stefan, Rosenwald, Andreas, Saliba, Antoine-Emmanuel, Bartfeld, Sina
Published in Nature communications (05.10.2022)
Published in Nature communications (05.10.2022)
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Journal Article
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
Starossom, Sarah C., Campo Garcia, Juliana, Woelfle, Tim, Romero-Suarez, Silvina, Olah, Marta, Watanabe, Fumihiro, Cao, Li, Yeste, Ada, Tukker, John J., Quintana, Francisco J., Imitola, Jaime, Witzel, Franziska, Schmitz, Dietmar, Morkel, Markus, Paul, Friedemann, Infante-Duarte, Carmen, Khoury, Samia J.
Published in Nature communications (15.01.2019)
Published in Nature communications (15.01.2019)
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Journal Article
c-Met is essential for wound healing in the skin
Chmielowiec, Jolanta, Borowiak, Malgorzata, Morkel, Markus, Stradal, Theresia, Munz, Barbara, Werner, Sabine, Wehland, Jürgen, Birchmeier, Carmen, Birchmeier, Walter
Published in The Journal of cell biology (09.04.2007)
Published in The Journal of cell biology (09.04.2007)
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Journal Article
DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer
Mamlouk, Soulafa, Childs, Liam Harold, Aust, Daniela, Heim, Daniel, Melching, Friederike, Oliveira, Cristiano, Wolf, Thomas, Durek, Pawel, Schumacher, Dirk, Bläker, Hendrik, von Winterfeld, Moritz, Gastl, Bastian, Möhr, Kerstin, Menne, Andrea, Zeugner, Silke, Redmer, Torben, Lenze, Dido, Tierling, Sascha, Möbs, Markus, Weichert, Wilko, Folprecht, Gunnar, Blanc, Eric, Beule, Dieter, Schäfer, Reinhold, Morkel, Markus, Klauschen, Frederick, Leser, Ulf, Sers, Christine
Published in Nature communications (25.01.2017)
Published in Nature communications (25.01.2017)
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Journal Article
Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression
Mamlouk, Soulafa, Simon, Tincy, Tomás, Laura, Wedge, David C, Arnold, Alexander, Menne, Andrea, Horst, David, Capper, David, Morkel, Markus, Posada, David, Sers, Christine, Bläker, Hendrik
Published in BMC biology (07.09.2020)
Published in BMC biology (07.09.2020)
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Journal Article
DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors
Simon, Tincy, Riemer, Pamela, Jarosch, Armin, Detjen, Katharina, Di Domenico, Annunziata, Bormann, Felix, Menne, Andrea, Khouja, Slim, Monjé, Nanna, Childs, Liam H, Lenze, Dido, Leser, Ulf, Rossner, Florian, Morkel, Markus, Blüthgen, Nils, Pavel, Marianne, Horst, David, Capper, David, Marinoni, Ilaria, Perren, Aurel, Mamlouk, Soulafa, Sers, Christine
Published in Genome medicine (01.03.2022)
Published in Genome medicine (01.03.2022)
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Journal Article
In vivo knockdown of Brachyury results in skeletal defects and urorectal malformations resembling caudal regression syndrome
Pennimpede, Tracie, Proske, Judith, König, Andrea, Vidigal, Joana A., Morkel, Markus, Bramsen, Jesper B., Herrmann, Bernhard G., Wittler, Lars
Published in Developmental biology (01.12.2012)
Published in Developmental biology (01.12.2012)
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Journal Article
Wnt and BMP signals control intestinal adenoma cell fates
Farrall, Alexandra L., Riemer, Pamela, Leushacke, Marc, Sreekumar, Amulya, Grimm, Christina, Herrmann, Bernhard G., Morkel, Markus
Published in International journal of cancer (15.11.2012)
Published in International journal of cancer (15.11.2012)
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Journal Article
SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
Klotz-Noack, Kathleen, Klinger, Bertram, Rivera, Maria, Bublitz, Natalie, Uhlitz, Florian, Riemer, Pamela, Lüthen, Mareen, Sell, Thomas, Kasack, Katharina, Gastl, Bastian, Ispasanie, Sylvia S.S., Simon, Tincy, Janssen, Nicole, Schwab, Matthias, Zuber, Johannes, Horst, David, Blüthgen, Nils, Schäfer, Reinhold, Morkel, Markus, Sers, Christine
Published in Cell reports (Cambridge) (22.09.2020)
Published in Cell reports (Cambridge) (22.09.2020)
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Journal Article
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells
Jürchott, Karsten, Kuban, Ralf-Jürgen, Krech, Till, Blüthgen, Nils, Stein, Ulrike, Walther, Wolfgang, Friese, Christian, Kiełbasa, Szymon M, Ungethüm, Ute, Lund, Per, Knösel, Thomas, Kemmner, Wolfgang, Morkel, Markus, Fritzmann, Johannes, Schlag, Peter M, Birchmeier, Walter, Krueger, Tammo, Sperling, Silke, Sers, Christine, Royer, Hans-Dieter, Herzel, Hanspeter, Schäfer, Reinhold
Published in PLoS genetics (01.12.2010)
Published in PLoS genetics (01.12.2010)
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Journal Article
DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer
Grimm, Christina, Chavez, Lukas, Vilardell, Mireia, Farrall, Alexandra L, Tierling, Sascha, Böhm, Julia W, Grote, Phillip, Lienhard, Matthias, Dietrich, Jörn, Timmermann, Bernd, Walter, Jörn, Schweiger, Michal R, Lehrach, Hans, Herwig, Ralf, Herrmann, Bernhard G, Morkel, Markus
Published in PLoS genetics (01.02.2013)
Published in PLoS genetics (01.02.2013)
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Journal Article
An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression
Leushacke, Marc, Spörle, Ralf, Bernemann, Christof, Brouwer-Lehmitz, Antje, Fritzmann, Johannes, Theis, Mirko, Buchholz, Frank, Herrmann, Bernhard G, Morkel, Markus
Published in PloS one (11.08.2011)
Published in PloS one (11.08.2011)
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Journal Article
A Role for E2F6 in the Restriction of Male-Germ-Cell-Specific Gene Expression
Pohlers, Michael, Truss, Matthias, Frede, Ute, Scholz, Axel, Strehle, Michael, Kuban, Ralf-Jürgen, Hoffmann, Bettina, Morkel, Markus, Birchmeier, Carmen, Hagemeier, Christian
Published in Current biology (07.06.2005)
Published in Current biology (07.06.2005)
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Journal Article
GPA33 expression in colorectal cancer can be induced by WNT inhibition and targeted by cellular therapy
Börding, Teresa, Janik, Tobias, Bischoff, Philip, Morkel, Markus, Sers, Christine, Horst, David
Published in Oncogene (29.10.2024)
Published in Oncogene (29.10.2024)
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Journal Article
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
Gassen, Nils C., Papies, Jan, Bajaj, Thomas, Emanuel, Jackson, Dethloff, Frederik, Chua, Robert Lorenz, Trimpert, Jakob, Heinemann, Nicolas, Niemeyer, Christine, Weege, Friderike, Hönzke, Katja, Aschman, Tom, Heinz, Daniel E., Weckmann, Katja, Ebert, Tim, Zellner, Andreas, Lennarz, Martina, Wyler, Emanuel, Schroeder, Simon, Richter, Anja, Niemeyer, Daniela, Hoffmann, Karen, Meyer, Thomas F., Heppner, Frank L., Corman, Victor M., Landthaler, Markus, Hocke, Andreas C., Morkel, Markus, Osterrieder, Nikolaus, Conrad, Christian, Eils, Roland, Radbruch, Helena, Giavalisco, Patrick, Drosten, Christian, Müller, Marcel A.
Published in Nature communications (21.06.2021)
Published in Nature communications (21.06.2021)
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