Amylovis-201 is a new dual-target ligand, acting as an anti-amyloidogenic compound and a potent agonist of the σ1 chaperone protein
García-Pupo, Laura, Crouzier, Lucie, Bencomo-Martínez, Alberto, Meunier, Johann, Morilleau, Axelle, Delprat, Benjamin, Carrazana, Marquiza Sablón, Menéndez Soto del Valle, Roberto, Maurice, Tangui, Rodríguez-Tanty, Chryslaine
Published in Acta pharmaceutica Sinica. B (01.10.2024)
Published in Acta pharmaceutica Sinica. B (01.10.2024)
Get full text
Journal Article
Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer?s Disease Mouse Model
Spatz, Philipp, Steinmueller, Sophie A. M., Tutov, Anna, Poeta, Eleonora, Morilleau, Axelle, Carles, Allison, Deventer, Marie H., Hofmann, Julian, Stove, Christophe P., Monti, Barbara, Maurice, Tangui, Decker, Michael
Published in Journal of medicinal chemistry (11.05.2023)
Published in Journal of medicinal chemistry (11.05.2023)
Get full text
Journal Article
Convolamine, a tropane alkaloid extracted from Convolvulus plauricalis, is a potent sigma‐1 receptor‐positive modulator with cognitive and neuroprotective properties
Crouzier, Lucie, Meunier, Johann, Carles, Allison, Morilleau, Axelle, Vrigneau, Cassandre, Schmitt, Martine, Bourguignon, Jean‐Jacques, Delprat, Benjamin, Maurice, Tangui
Published in Phytotherapy research (01.02.2024)
Published in Phytotherapy research (01.02.2024)
Get full text
Journal Article
Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer’s Disease Mouse Model
Spatz, Philipp, Steinmüller, Sophie A. M., Tutov, Anna, Poeta, Eleonora, Morilleau, Axelle, Carles, Allison, Deventer, Marie H., Hofmann, Julian, Stove, Christophe P., Monti, Barbara, Maurice, Tangui, Decker, Michael
Published in Journal of medicinal chemistry (11.05.2023)
Published in Journal of medicinal chemistry (11.05.2023)
Get full text
Journal Article