Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead
Moriarty, Kevin J., Winters, Michael, Qiao, Lei, Ryan, Declan, DesJarlis, Renee, Robinson, Darius, Cook, Brian N., Kashem, Mohammed A., Kaplita, Paul V., Liu, Lisa H., Farrell, Thomas M., Khine, Hnin Hnin, King, Josephine, Pullen, Steven S., Roth, Gregory P., Magolda, Ronald, Takahashi, Hidenori
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
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Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists
Chiba, Jun, Takayama, Gensuke, Takashi, Tohru, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Moriarty, Kevin J., Sarko, Christopher R., Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela, Machinaga, Nobuo
Published in Bioorganic & medicinal chemistry (15.04.2006)
Published in Bioorganic & medicinal chemistry (15.04.2006)
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Studies on the Synthesis of Nargenicin A1: Highly Stereoselective Synthesis of the Complete Carbon Framework via the Transannular Diels−Alder Reaction of an 18-Membered Macrolide
Roush, William R, Koyama, Kazuo, Curtin, Michael L, Moriarty, Kevin J
Published in Journal of the American Chemical Society (14.08.1996)
Published in Journal of the American Chemical Society (14.08.1996)
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The synthesis and SAR of 2-amino-pyrrolo[2,3- d]pyrimidines: A new class of Aurora-A kinase inhibitors
Moriarty, Kevin J., Koblish, Holly K., Garrabrant, Thomas, Maisuria, Jahanvi, Khalil, Ehab, Ali, Farah, Petrounia, Ioanna P., Crysler, Carl S., Maroney, Anna C., Johnson, Dana L., Galemmo, Robert A.
Published in Bioorganic & medicinal chemistry letters (15.11.2006)
Published in Bioorganic & medicinal chemistry letters (15.11.2006)
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Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)
MORIARTY, Kevin J, TAKAHASHI, Hidenori, LEI QIAO, RYAN, Declan, DESJARLAIS, Renee, ROBINSON, Darius, WILSON, Matthew, BOBKO, Mark, COOK, Brian N, HO YIN LO, NEMOTO, Peter A, KASHEM, Mohammed A, PULLEN, Steven S, WOLAK, John P, WHITE, André, MAGOLDA, Ronald L, TOMCZUK, Bruce, HNIN HNIN KHINE, SALLATI, Rosemarie H, RAYMOND, Ernest L, WOSKA, Joseph R, JEANFAVRE, Deborah D, ROTH, Gregory P, WINTERS, Michael P
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
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The Discovery of Orally Active Triaminotriazine Aniline Amides as Inhibitors of p38 MAP Kinase
Leftheris, Katerina, Ahmed, Gulzar, Chan, Ran, Dyckman, Alaric J, Hussain, Zahid, Ho, Kan, Hynes, John, Letourneau, Jeffrey, Li, Wei, Lin, Shuqun, Metzger, Axel, Moriarty, Kevin J, Riviello, Chris, Shimshock, Yvonne, Wen, James, Wityak, John, Wrobleski, Stephen T, Wu, Hong, Wu, Junjun, Desai, Madhuri, Gillooly, Kathleen M, Lin, Tsung H, Loo, Derek, McIntyre, Kim W, Pitt, Sidney, Shen, Ding Ren, Shuster, David J, Zhang, Rosemary, Diller, David, Doweyko, Arthur, Sack, John, Baldwin, Jack, Barrish, Joel, Dodd, John, Henderson, Ian, Kanner, Steve, Schieven, Gary L, Webb, Maria
Published in Journal of medicinal chemistry (02.12.2004)
Published in Journal of medicinal chemistry (02.12.2004)
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Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors
Qiao, Lei, Baumann, Christian A., Crysler, Carl S., Ninan, Nisha S., Abad, Marta C., Spurlino, John C., DesJarlais, Renee L., Kervinen, Jukka, Neeper, Mike P., Bayoumy, Shariff S., Williams, Robyn, Deckman, Ingrid C., Dasgupta, Malini, Reed, Rolanda L., Huebert, Norman D., Tomczuk, Bruce E., Moriarty, Kevin J.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Comprehensive Survey of Combinatorial Library Synthesis: 2005
Dolle, Roland E, Le Bourdonnec, Bertrand, Morales, Guillermo A, Moriarty, Kevin J, Salvino, Joseph M
Published in Journal of combinatorial chemistry (01.09.2006)
Published in Journal of combinatorial chemistry (01.09.2006)
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Journal Article
Enantioselective synthesis of the bottom half of chlorothricolide. 3. Studies of the steric directing group strategy for stereocontrol in intramolecular Diels-Alder reactions
Roush, William R, Kageyama, Masanori, Riva, Renata, Brown, Bradley B, Warmus, Joseph S, Moriarty, Kevin J
Published in Journal of organic chemistry (01.02.1991)
Published in Journal of organic chemistry (01.02.1991)
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Synthetic, x-ray structural and photoluminescence studies on pentamethylcyclopentadienyl derivatives of lanthanum, cerium and praseodymium
Rausch, Marvin D, Moriarty, Kevin J, Atwood, Jerry L, Weeks, James A, Hunter, William E, Brittain, Harry G
Published in Organometallics (01.06.1986)
Published in Organometallics (01.06.1986)
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A Novel Series of [2-[Methyl(2-phenethyl)amino]-2-oxoethyl]benzene-Containing Leukotriene B4 Antagonists: Initial Structure−Activity Relationships
Huang, Fu-Chih, Chan, Wan-Kit, Moriarty, Kevin J, Poli, Gregory, Morrissette, Matthew M, Galemmo, Robert A, Warus, James D, Dankulich, William P, Sutherland, Charles A
Published in Journal of medicinal chemistry (13.09.1996)
Published in Journal of medicinal chemistry (13.09.1996)
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Journal Article
Structure−Activity Relationships Study of Two Series of Leukotriene B4 Antagonists: Novel Indolyl and Naphthyl Compounds Substituted with a 2-[Methyl(2-phenethyl)amino]-2-oxoethyl Side Chain
Chan, Wan K, Huang, Fu-Chih, Morrissette, Matthew M, Warus, James D, Moriarty, Kevin J, Galemmo, Robert A, Dankulich, William D, Poli, Gregory, Sutherland, Charles A
Published in Journal of medicinal chemistry (13.09.1996)
Published in Journal of medicinal chemistry (13.09.1996)
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4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2-naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist
Huang, Fu Chih, Chan, Wan Kit, Warus, James D, Morrissette, Mathew M, Moriarty, Kevin J, Chang, Michael N, Travis, Jeffrey J, Mitchell, Laurie S, Nuss, George W, Sutherland, Charles A
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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Isodicyclopentadienes and related molecules. 45. (1R)-(-)-Nopol as the source of an optically pure fused cyclopentadienyl ligand. Stereochemical course of complexation to cyclopentadienyltitanium and -zirconium dichloride fragments [Erratum to document cited in CA111(1):7549e]
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Isodicyclopentadienes and related molecules. Part 40. Stereocontrolled bifacial complexation of the isodicyclopentadienyl ligand to cyclopentadienyltitanium dichloride fragments
Paquette, Leo A, Moriarty, Kevin J, Meunier, Philippe, Gautheron, Bernard, Crocq, Veronique
Published in Organometallics (01.08.1988)
Published in Organometallics (01.08.1988)
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