Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
Webber, Beau R., Lonetree, Cara-lin, Kluesner, Mitchell G., Johnson, Matthew J., Pomeroy, Emily J., Diers, Miechaleen D., Lahr, Walker S., Draper, Garrett M., Slipek, Nicholas J., Smeester, Branden A., Lovendahl, Klaus N., McElroy, Amber N., Gordon, Wendy R., Osborn, Mark J., Moriarity, Branden S.
Published in Nature communications (19.11.2019)
Published in Nature communications (19.11.2019)
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Journal Article
EditR: A Method to Quantify Base Editing from Sanger Sequencing
Kluesner, Mitchell G., Nedveck, Derek A., Lahr, Walker S., Garbe, John R., Abrahante, Juan E., Webber, Beau R., Moriarity, Branden S.
Published in CRISPR journal (01.06.2018)
Published in CRISPR journal (01.06.2018)
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Journal Article
CRISPR/Cas9 library screening for drug target discovery
Kurata, Morito, Yamamoto, Kouhei, Moriarity, Branden S, Kitagawa, Masanobu, Largaespada, David A
Published in Journal of human genetics (01.02.2018)
Published in Journal of human genetics (01.02.2018)
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Journal Article
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy
Pomeroy, Emily J., Hunzeker, John T., Kluesner, Mitchell G., Lahr, Walker S., Smeester, Branden A., Crosby, Margaret R., Lonetree, Cara-lin, Yamamoto, Kenta, Bendzick, Laura, Miller, Jeffrey S., Geller, Melissa A., Walcheck, Bruce, Felices, Martin, Webber, Beau R., Starr, Timothy K., Moriarity, Branden S.
Published in Molecular therapy (08.01.2020)
Published in Molecular therapy (08.01.2020)
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Journal Article
Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease
Johnson, Matthew J., Laoharawee, Kanut, Lahr, Walker S., Webber, Beau R., Moriarity, Branden S.
Published in Scientific reports (14.08.2018)
Published in Scientific reports (14.08.2018)
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Journal Article
Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments
Tabdanov, Erdem D., Rodríguez-Merced, Nelson J., Cartagena-Rivera, Alexander X., Puram, Vikram V., Callaway, Mackenzie K., Ensminger, Ethan A., Pomeroy, Emily J., Yamamoto, Kenta, Lahr, Walker S., Webber, Beau R., Moriarity, Branden S., Zhovmer, Alexander S., Provenzano, Paolo P.
Published in Nature communications (14.05.2021)
Published in Nature communications (14.05.2021)
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Journal Article
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells
Kluesner, Mitchell G., Lahr, Walker S., Lonetree, Cara-lin, Smeester, Branden A., Qiu, Xiaohong, Slipek, Nicholas J., Claudio Vázquez, Patricia N., Pitzen, Samuel P., Pomeroy, Emily J., Vignes, Madison J., Lee, Samantha C., Bingea, Samuel P., Andrew, Aneesha A., Webber, Beau R., Moriarity, Branden S.
Published in Nature communications (23.04.2021)
Published in Nature communications (23.04.2021)
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Journal Article
A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers
Wong, Derek P., Roy, Nand K., Zhang, Keman, Anukanth, Anusha, Asthana, Abhishek, Shirkey-Son, Nicole J., Dunmire, Samantha, Jones, Bryan J., Lahr, Walker S., Webber, Beau R., Moriarity, Branden S., Caimi, Paolo, Parameswaran, Reshmi
Published in Nature communications (11.01.2022)
Published in Nature communications (11.01.2022)
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Journal Article
Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Scott, Milcah C, Temiz, Nuri A, Sarver, Anne E, LaRue, Rebecca S, Rathe, Susan K, Varshney, Jyotika, Wolf, Natalie K, Moriarity, Branden S, O'Brien, Timothy D, Spector, Logan G, Largaespada, David A, Modiano, Jaime F, Subramanian, Subbaya, Sarver, Aaron L
Published in Cancer research (Chicago, Ill.) (15.01.2018)
Published in Cancer research (Chicago, Ill.) (15.01.2018)
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Journal Article
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
Huang, Miller, Tailor, Jignesh, Zhen, Qiqi, Gillmor, Aaron H., Miller, Matthew L., Weishaupt, Holger, Chen, Justin, Zheng, Tina, Nash, Emily K., McHenry, Lauren K., An, Zhenyi, Ye, Fubaiyang, Takashima, Yasuhiro, Clarke, James, Ayetey, Harold, Cavalli, Florence M.G., Luu, Betty, Moriarity, Branden S., Ilkhanizadeh, Shirin, Chavez, Lukas, Yu, Chunying, Kurian, Kathreena M., Magnaldo, Thierry, Sevenet, Nicolas, Koch, Philipp, Pollard, Steven M., Dirks, Peter, Snyder, Michael P., Largaespada, David A., Cho, Yoon Jae, Phillips, Joanna J., Swartling, Fredrik J., Morrissy, A. Sorana, Kool, Marcel, Pfister, Stefan M., Taylor, Michael D., Smith, Austin, Weiss, William A.
Published in Cell stem cell (05.09.2019)
Published in Cell stem cell (05.09.2019)
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Journal Article
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays
Kurata, Morito, Wolf, Natalie K, Lahr, Walker S, Weg, Madison T, Kluesner, Mitchell G, Lee, Samantha, Hui, Kai, Shiraiwa, Masano, Webber, Beau R, Moriarity, Branden S
Published in PloS one (17.09.2018)
Published in PloS one (17.09.2018)
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Journal Article
Efficient targeted integration directed by short homology in zebrafish and mammalian cells
Wierson, Wesley A, Welker, Jordan M, Almeida, Maira P, Mann, Carla M, Webster, Dennis A, Torrie, Melanie E, Weiss, Trevor J, Kambakam, Sekhar, Vollbrecht, Macy K, Lan, Merrina, McKeighan, Kenna C, Levey, Jacklyn, Ming, Zhitao, Wehmeier, Alec, Mikelson, Christopher S, Haltom, Jeffrey A, Kwan, Kristen M, Chien, Chi-Bin, Balciunas, Darius, Ekker, Stephen C, Clark, Karl J, Webber, Beau R, Moriarity, Branden S, Solin, Stacy L, Carlson, Daniel F, Dobbs, Drena L, McGrail, Maura, Essner, Jeffrey
Published in eLife (15.05.2020)
Published in eLife (15.05.2020)
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Journal Article
Nonviral genome engineering of natural killer cells
Robbins, Gabrielle M, Wang, Minjing, Pomeroy, Emily J, Moriarity, Branden S
Published in Stem cell research & therapy (16.06.2021)
Published in Stem cell research & therapy (16.06.2021)
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Journal Article
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis
Rahrmann, Eric P, Watson, Adrienne L, Keng, Vincent W, Choi, Kwangmin, Moriarity, Branden S, Beckmann, Dominic A, Wolf, Natalie K, Sarver, Aaron, Collins, Margaret H, Moertel, Christopher L, Wallace, Margaret R, Gel, Bernat, Serra, Eduard, Ratner, Nancy, Largaespada, David A
Published in Nature genetics (01.07.2013)
Published in Nature genetics (01.07.2013)
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Journal Article
Germline T cell receptor exchange results in physiological T cell development and function
Rollins, Meagan R., Raynor, Jackson F., Miller, Ebony A., Butler, Jonah Z., Spartz, Ellen J., Lahr, Walker S., You, Yun, Burrack, Adam L., Moriarity, Branden S., Webber, Beau R., Stromnes, Ingunn M.
Published in Nature communications (01.02.2023)
Published in Nature communications (01.02.2023)
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Journal Article
PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma
Smeester, Branden A., Slipek, Nicholas J., Pomeroy, Emily J., Laoharawee, Kanut, Osum, Sara H., Larsson, Alex T., Williams, Kyle B., Stratton, Natalie, Yamamoto, Kenta, Peterson, Joseph J., Rathe, Susan K., Mills, Lauren J., Hudson, Wendy A., Crosby, Margaret R., Wang, Minjing, Rahrmann, Eric P., Moriarity, Branden S., Largaespada, David A.
Published in Bone (New York, N.Y.) (01.07.2020)
Published in Bone (New York, N.Y.) (01.07.2020)
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Journal Article
Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3
Chaudhary, Ritu, Gryder, Berkley, Woods, Wendy S, Subramanian, Murugan, Jones, Matthew F, Li, Xiao Ling, Jenkins, Lisa M, Shabalina, Svetlana A, Mo, Min, Dasso, Mary, Yang, Yuan, Wakefield, Lalage M, Zhu, Yuelin, Frier, Susan M, Moriarity, Branden S, Prasanth, Kannanganattu V, Perez-Pinera, Pablo, Lal, Ashish
Published in eLife (05.06.2017)
Published in eLife (05.06.2017)
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Journal Article
HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism
Chiu, Amy P, Tschida, Barbara R, Sham, Tung-Ting, Lo, Lilian H, Moriarity, Branden S, Li, Xiao-Xiao, Lo, Regina C, Hinton, David E, Rowlands, Dewi K, Chan, Chi-On, Mok, Daniel K W, Largaespada, David A, Warner, Nadia, Keng, Vincent W
Published in Molecular cancer research (01.07.2019)
Published in Molecular cancer research (01.07.2019)
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Journal Article
Genetic and epigenetic modification of human primary NK cells for enhanced antitumor activity
Naeimi Kararoudi, Meisam, Tullius, Brian P, Chakravarti, Nitin, Pomeroy, Emily J, Moriarity, Branden S, Beland, Kathie, Colamartino, Aurelien B L, Haddad, Elie, Chu, Yaya, Cairo, Mitchell S, Lee, Dean A
Published in Seminars in hematology (01.10.2020)
Published in Seminars in hematology (01.10.2020)
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Journal Article
RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens
Temiz, Nuri A, Moriarity, Branden S, Wolf, Natalie K, Riordan, Jesse D, Dupuy, Adam J, Largaespada, David A, Sarver, Aaron L
Published in Genome research (01.01.2016)
Published in Genome research (01.01.2016)
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