11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess
Morgan, Stuart A, McCabe, Emma L, Gathercole, Laura L, Hassan-Smith, Zaki K, Larner, Dean P, Bujalska, Iwona J, Stewart, Paul M, Tomlinson, Jeremy W, Lavery, Gareth G
Published in Proceedings of the National Academy of Sciences - PNAS (17.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (17.06.2014)
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Journal Article
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
Gathercole, Laura L, Morgan, Stuart A, Bujalska, Iwona J, Hauton, David, Stewart, Paul M, Tomlinson, Jeremy W
Published in PloS one (14.10.2011)
Published in PloS one (14.10.2011)
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Journal Article
11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice
Doig, Craig L., Fletcher, Rachel S., Morgan, Stuart A., McCabe, Emma L., Larner, Dean P., Tomlinson, Jeremy W., Stewart, Paul M., Philp, Andrew, Lavery, Gareth G.
Published in Endocrinology (Philadelphia) (01.06.2017)
Published in Endocrinology (Philadelphia) (01.06.2017)
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Journal Article
MECHANISMS IN ENDOCRINOLOGY: Tissue-specific activation of cortisol in Cushing’s syndrome
Morgan, Stuart A, Hassan-Smith, Zaki K, Lavery, Gareth G
Published in European journal of endocrinology (01.08.2016)
Published in European journal of endocrinology (01.08.2016)
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Journal Article
11β-Hydroxysteroid Dehydrogenase Type 1 Regulates Glucocorticoid-Induced Insulin Resistance in Skeletal Muscle
MORGAN, Stuart A, SHERLOCK, Mark, HEGYI, Krisztina, SETHI, Jaswinder K, STEWART, Paul M, SMITH, David M, TOMLINSON, Jeremy W, GATHERCOLE, Laura L, LAVERY, Gareth G, LENAGHAN, Carol, BUJALSKA, Iwona J, LABER, David, YU, Alice, CONVEY, Gemma, MAYERS, Rachel
Published in Diabetes (New York, N.Y.) (01.11.2009)
Published in Diabetes (New York, N.Y.) (01.11.2009)
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Journal Article
25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression
Hassan-Smith, Zaki K, Jenkinson, Carl, Smith, David J, Hernandez, Ivan, Morgan, Stuart A, Crabtree, Nicola J, Gittoes, Neil J, Keevil, Brian G, Stewart, Paul M, Hewison, Martin
Published in PloS one (15.02.2017)
Published in PloS one (15.02.2017)
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Journal Article
Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid[S]
Penno, Carlos A., Morgan, Stuart A., Vuorinen, Anna, Schuster, Daniela, Lavery, Gareth G., Odermatt, Alex
Published in Journal of lipid research (01.10.2013)
Published in Journal of lipid research (01.10.2013)
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Journal Article
11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects
Tiganescu, Ana, Tahrani, Abd A, Morgan, Stuart A, Otranto, Marcela, Desmouliere, Alexis, Abrahams, Lianne, Hassan-Smith, Zaki, Walker, Elizabeth A, Rabbitt, Elizabeth H, Cooper, Mark S, Kurt, Amrein, Lavery, Gareth G, Stewart, Paul M
Published in The Journal of clinical investigation (01.07.2013)
Published in The Journal of clinical investigation (01.07.2013)
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Journal Article
The CRH-Transgenic Cushingoid Mouse Is a Model of Glucocorticoid-Induced Osteoporosis
Williams-Dautovich, Jasmine, Yogendirarajah, Keertika, Dela Cruz, Ariana, Patel, Rucha, Tsai, Ricky, Morgan, Stuart A, Mitchell, Jane, Grynpas, Marc D, Cummins, Carolyn L
Published in JBMR plus (01.08.2017)
Published in JBMR plus (01.08.2017)
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Journal Article
11β-HSD1 contributes to age-related metabolic decline in male mice
Morgan, Stuart A, Gathercole, Laura L, Hassan-Smith, Zaki K, Tomlinson, Jeremy, Stewart, Paul M, Lavery, Gareth G
Published in Journal of endocrinology (01.12.2022)
Published in Journal of endocrinology (01.12.2022)
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Journal Article
11β-Hydroxysteroid Dehydrogenase 1: Translational and Therapeutic Aspects
Gathercole, Laura L, Lavery, Gareth G, Morgan, Stuart A, Cooper, Mark S, Sinclair, Alexandra J, Tomlinson, Jeremy W, Stewart, Paul M
Published in Endocrine reviews (01.08.2013)
Published in Endocrine reviews (01.08.2013)
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Journal Article
11 beta -Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects
Tiganescu, Ana, Tahrani, Abd A, Morgan, Stuart A, Otranto, Marcela, Desmouliere, Alexis, Abrahams, Lianne, Hassan-Smith, Zaki, Walker, Elizabeth A, Rabbitt, Elizabeth H, Cooper, Mark S, Amrein, Kurt, Lavery, Gareth G, Stewart, Paul M
Published in The Journal of clinical investigation (01.07.2013)
Published in The Journal of clinical investigation (01.07.2013)
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Journal Article
Gender-Specific Differences in Skeletal Muscle 11β-HSD1 Expression Across Healthy Aging
Hassan-Smith, Zaki K, Morgan, Stuart A, Sherlock, Mark, Hughes, Beverly, Taylor, Angela E, Lavery, Gareth G, Tomlinson, Jeremy W, Stewart, Paul M
Published in The journal of clinical endocrinology and metabolism (01.07.2015)
Published in The journal of clinical endocrinology and metabolism (01.07.2015)
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Journal Article
Regulation of 11β-HSD1 by GH/IGF-1 in key metabolic tissues may contribute to metabolic disease in GH deficient patients
Morgan, Stuart A., Berryman, Darlene E., List, Edward O., Lavery, Gareth G., Stewart, Paul M., Kopchick, John J.
Published in Growth hormone & IGF research (01.02.2022)
Published in Growth hormone & IGF research (01.02.2022)
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Journal Article
11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation
Hardy, Rowan S, Doig, Craig L, Hussain, Zahrah, O'Leary, Mary, Morgan, Stuart A, Pearson, Mark J, Naylor, Amy, Jones, Simon W, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Lavery, Gareth G, Cooper, Mark S, Raza, Karim
Published in The Journal of pathology (01.12.2016)
Published in The Journal of pathology (01.12.2016)
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Journal Article
11[beta]-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation
Hardy, Rowan S, Doig, Craig L, Hussain, Zahrah, O'Leary, Mary, Morgan, Stuart A, Pearson, Mark J, Naylor, Amy, Jones, Simon W, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Lavery, Gareth G, Cooper, Mark S, Raza, Karim
Published in The Journal of pathology (01.12.2016)
Published in The Journal of pathology (01.12.2016)
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Journal Article
Loss of 5α-Reductase Type 1 Accelerates the Development of Hepatic Steatosis but Protects Against Hepatocellular Carcinoma in Male Mice
Dowman, Joanna K, Hopkins, Laurence J, Reynolds, Gary M, Armstrong, Matthew J, Nasiri, Maryam, Nikolaou, Nikolaos, van Houten, E. Leonie A. F, Visser, Jenny A, Morgan, Stuart A, Lavery, Gareth G, Oprescu, Andrei, Hübscher, Stefan G, Newsome, Philip N, Tomlinson, Jeremy W
Published in Endocrinology (Philadelphia) (01.12.2013)
Published in Endocrinology (Philadelphia) (01.12.2013)
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Journal Article
Lack of Significant Metabolic Abnormalities in Mice with Liver-Specific Disruption of 11β-Hydroxysteroid Dehydrogenase Type 1
Lavery, Gareth G, Zielinska, Agnieszka E, Gathercole, Laura L, Hughes, Beverly, Semjonous, Nina, Guest, Phillip, Saqib, Khalid, Sherlock, Mark, Reynolds, Gary, Morgan, Stuart A, Tomlinson, Jeremy W, Walker, Elizabeth A, Rabbitt, Elizabeth H, Stewart, Paul M
Published in Endocrinology (Philadelphia) (01.07.2012)
Published in Endocrinology (Philadelphia) (01.07.2012)
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Journal Article
Male 11[beta]-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease
Larner, Dean P, Morgan, Stuart A, Gathercole, Laura L, Doig, Craig L, Guest, Phil, Weston, Christopher, Hazeldine, Jon, Tomlinson, Jeremy W, Stewart, Paul M, Lavery, Gareth G
Published in Endocrinology (Philadelphia) (01.09.2016)
Published in Endocrinology (Philadelphia) (01.09.2016)
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Journal Article