Light activation of Orange Carotenoid Protein reveals bicycle-pedal single-bond isomerization
Chukhutsina, Volha U., Baxter, James M., Fadini, Alisia, Morgan, Rhodri M., Pope, Matthew A., Maghlaoui, Karim, Orr, Christian M., Wagner, Armin, van Thor, Jasper J.
Published in Nature communications (28.10.2022)
Published in Nature communications (28.10.2022)
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Journal Article
Auxiliary interfaces support the evolution of specific toxin–antitoxin pairing
Grabe, Grzegorz J., Giorgio, Rachel T., Hall, Alexander M. J., Morgan, Rhodri M. L., Dubois, Laurent, Sisley, Tyler A., Rycroft, Julian A., Hare, Stephen A., Helaine, Sophie
Published in Nature chemical biology (01.12.2021)
Published in Nature chemical biology (01.12.2021)
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Journal Article
Rapid Proteasomal Degradation of Mutant Proteins Is the Primary Mechanism Leading to Tumorigenesis in Patients With Missense AIP Mutations
Hernández-Ramírez, Laura C, Martucci, Federico, Morgan, Rhodri M. L, Trivellin, Giampaolo, Tilley, Daniel, Ramos-Guajardo, Nancy, Iacovazzo, Donato, D'Acquisto, Fulvio, Prodromou, Chrisostomos, Korbonits, Márta
Published in The journal of clinical endocrinology and metabolism (01.08.2016)
Published in The journal of clinical endocrinology and metabolism (01.08.2016)
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Journal Article
High‐Throughput Kinetic Analysis for Target‐Directed Covalent Ligand Discovery
Craven, Gregory B., Affron, Dominic P., Allen, Charlotte E., Matthies, Stefan, Greener, Joe G., Morgan, Rhodri M. L., Tate, Edward W., Armstrong, Alan, Mann, David J.
Published in Angewandte Chemie International Edition (04.05.2018)
Published in Angewandte Chemie International Edition (04.05.2018)
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Journal Article
Structure of the TPR domain of AIP: lack of client protein interaction with the C-terminal α-7 helix of the TPR domain of AIP is sufficient for pituitary adenoma predisposition
Morgan, Rhodri M L, Hernández-Ramírez, Laura C, Trivellin, Giampaolo, Zhou, Lihong, Roe, S Mark, Korbonits, Márta, Prodromou, Chrisostomos
Published in PloS one (31.12.2012)
Published in PloS one (31.12.2012)
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Journal Article
X-ray Free Electron Laser Determination of Crystal Structures of Dark and Light States of a Reversibly Photoswitching Fluorescent Protein at Room Temperature
Hutchison, Christopher D M, Cordon-Preciado, Violeta, Morgan, Rhodri M L, Nakane, Takanori, Ferreira, Josie, Dorlhiac, Gabriel, Sanchez-Gonzalez, Alvaro, Johnson, Allan S, Fitzpatrick, Ann, Fare, Clyde, Marangos, Jon P, Yoon, Chun Hong, Hunter, Mark S, DePonte, Daniel P, Boutet, Sébastien, Owada, Shigeki, Tanaka, Rie, Tono, Kensuke, Iwata, So, van Thor, Jasper J
Published in International journal of molecular sciences (07.09.2017)
Published in International journal of molecular sciences (07.09.2017)
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Journal Article
Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp
Krysztofinska, Ewelina M, Evans, Nicola J, Thapaliya, Arjun, Murray, James W, Morgan, Rhodri M L, Martinez-Lumbreras, Santiago, Isaacson, Rivka L
Published in Frontiers in molecular biosciences (11.10.2017)
Published in Frontiers in molecular biosciences (11.10.2017)
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Journal Article
Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM
Pathania, Monisha, Tosi, Tommaso, Millership, Charlotte, Hoshiga, Fumiya, Morgan, Rhodri M.L., Freemont, Paul S., Gründling, Angelika
Published in The Journal of biological chemistry (01.11.2021)
Published in The Journal of biological chemistry (01.11.2021)
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Journal Article
Bacillus subtilis YngB contributes to wall teichoic acid glucosylation and glycolipid formation during anaerobic growth
Wu, Chih-Hung, Rismondo, Jeanine, Morgan, Rhodri M.L., Shen, Yang, Loessner, Martin J., Larrouy-Maumus, Gerald, Freemont, Paul S., Gründling, Angelika
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Sequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β‑Sheet Fibrils
Wang, Shih-Ting, Lin, Yiyang, Spencer, Ryan K, Thomas, Michael R, Nguyen, Andy I, Amdursky, Nadav, Pashuck, E. Thomas, Skaalure, Stacey C, Song, Cheng Yu, Parmar, Paresh A, Morgan, Rhodri M, Ercius, Peter, Aloni, Shaul, Zuckermann, Ronald N, Stevens, Molly M
Published in ACS nano (26.09.2017)
Published in ACS nano (26.09.2017)
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Journal Article
Optical control of ultrafast structural dynamics in a fluorescent protein
Hutchison, Christopher D. M., Baxter, James M., Fitzpatrick, Ann, Dorlhiac, Gabriel, Fadini, Alisia, Perrett, Samuel, Maghlaoui, Karim, Lefèvre, Salomé Bodet, Cordon-Preciado, Violeta, Ferreira, Josie L., Chukhutsina, Volha U., Garratt, Douglas, Barnard, Jonathan, Galinis, Gediminas, Glencross, Flo, Morgan, Rhodri M., Stockton, Sian, Taylor, Ben, Yuan, Letong, Romei, Matthew G., Lin, Chi-Yun, Marangos, Jon P., Schmidt, Marius, Chatrchyan, Viktoria, Buckup, Tiago, Morozov, Dmitry, Park, Jaehyun, Park, Sehan, Eom, Intae, Kim, Minseok, Jang, Dogeun, Choi, Hyeongi, Hyun, HyoJung, Park, Gisu, Nango, Eriko, Tanaka, Rie, Owada, Shigeki, Tono, Kensuke, DePonte, Daniel P., Carbajo, Sergio, Seaberg, Matt, Aquila, Andrew, Boutet, Sebastien, Barty, Anton, Iwata, So, Boxer, Steven G., Groenhof, Gerrit, van Thor, Jasper J.
Published in Nature chemistry (01.11.2023)
Published in Nature chemistry (01.11.2023)
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Journal Article
Multiparameter Kinetic Analysis for Covalent Fragment Optimization by Using Quantitative Irreversible Tethering (qIT)
Craven, Gregory B., Affron, Dominic P., Kösel, Teresa, Wong, Tsz Lam M., Jukes, Zoë H., Liu, Chun‐Ting, Morgan, Rhodri M. L., Armstrong, Alan, Mann, David J.
Published in Chembiochem : a European journal of chemical biology (01.12.2020)
Published in Chembiochem : a European journal of chemical biology (01.12.2020)
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Journal Article
GenoChemetic Strategy for Derivatization of the Violacein Natural Product Scaffold
Lai, Hung-En, Obled, Alan M. C, Chee, Soo Mei, Morgan, Rhodri M, Lynch, Rosemary, Sharma, Sunil V, Moore, Simon J, Polizzi, Karen M, Goss, Rebecca J. M, Freemont, Paul S
Published in ACS chemical biology (19.11.2021)
Published in ACS chemical biology (19.11.2021)
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Journal Article
Identification of the first structurally validated covalent ligands of the small GTPase RAB27A
Jamshidiha, Mostafa, Lanyon-Hogg, Thomas, Sutherell, Charlotte L, Craven, Gregory B, Tersa, Montse, De Vita, Elena, Brustur, Delia, Pérez-Dorado, Inmaculada, Hassan, Sarah, Petracca, Rita, Morgan, Rhodri M, Sanz-Hernández, Máximo, Norman, Jim C, Armstrong, Alan, Mann, David J, Cota, Ernesto, Tate, Edward W
Published in MedChemComm (23.02.2022)
Published in MedChemComm (23.02.2022)
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Journal Article
Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease
Qin, Bo, Craven, Gregory B., Hou, Pengjiao, Chesti, Julian, Lu, Xinran, Child, Emma S., Morgan, Rhodri M.L., Niu, Wenchao, Zhao, Lina, Armstrong, Alan, Mann, David J., Cui, Sheng
Published in Acta pharmaceutica Sinica. B (01.10.2022)
Published in Acta pharmaceutica Sinica. B (01.10.2022)
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Journal Article
High‐Throughput Kinetic Analysis for Target‐Directed Covalent Ligand Discovery
Craven, Gregory B., Affron, Dominic P., Allen, Charlotte E., Matthies, Stefan, Greener, Joe G., Morgan, Rhodri M. L., Tate, Edward W., Armstrong, Alan, Mann, David J.
Published in Angewandte Chemie (04.05.2018)
Published in Angewandte Chemie (04.05.2018)
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Journal Article
Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland
Hernández-Ramírez, Laura C, Morgan, Rhodri M L, Barry, Sayka, D'Acquisto, Fulvio, Prodromou, Chrisostomos, Korbonits, Márta
Published in Oncotarget (06.02.2018)
Published in Oncotarget (06.02.2018)
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Journal Article
c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells
Dunn, Diana M., Woodford, Mark R., Truman, Andrew W., Jensen, Sandra M., Schulman, Jacqualyn, Caza, Tiffany, Remillard, Taylor C., Loiselle, David, Wolfgeher, Donald, Blagg, Brian S.J., Franco, Lucas, Haystead, Timothy A., Daturpalli, Soumya, Mayer, Matthias P., Trepel, Jane B., Morgan, Rhodri M.L., Prodromou, Chrisostomos, Kron, Stephen J., Panaretou, Barry, Stetler-Stevenson, William G., Landas, Steve K., Neckers, Len, Bratslavsky, Gennady, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (11.08.2015)
Published in Cell reports (Cambridge) (11.08.2015)
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Journal Article
Structure of the TPR Domain of AIP: Lack of Client Protein Interaction with the C-Terminal [alpha]-7 Helix of the TPR Domain of AIP Is Sufficient for Pituitary Adenoma Predisposition
Morgan, Rhodri M. L, Hernández-Ramírez, Laura C, Trivellin, Giampaolo, Zhou, Lihong, Roe, S. Mark, Korbonits, Márta, Prodromou, Chrisostomos
Published in PloS one (31.12.2012)
Published in PloS one (31.12.2012)
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Journal Article