Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease
Flanagan, Sarah E, Haapaniemi, Emma, Russell, Mark A, Caswell, Richard, Allen, Hana Lango, De Franco, Elisa, McDonald, Timothy J, Rajala, Hanna, Ramelius, Anita, Barton, John, Heiskanen, Kaarina, Heiskanen-Kosma, Tarja, Kajosaari, Merja, Murphy, Nuala P, Milenkovic, Tatjana, Seppänen, Mikko, Lernmark, Åke, Mustjoki, Satu, Otonkoski, Timo, Kere, Juha, Morgan, Noel G, Ellard, Sian, Hattersley, Andrew T
Published in Nature genetics (2014)
Published in Nature genetics (2014)
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Journal Article
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells
Colli, Maikel L., Ramos-Rodríguez, Mireia, Nakayasu, Ernesto S., Alvelos, Maria I., Lopes, Miguel, Hill, Jessica L. E., Turatsinze, Jean-Valery, Coomans de Brachène, Alexandra, Russell, Mark A., Raurell-Vila, Helena, Castela, Angela, Juan-Mateu, Jonàs, Webb-Robertson, Bobbie-Jo M., Krogvold, Lars, Dahl-Jorgensen, Knut, Marselli, Lorella, Marchetti, Piero, Richardson, Sarah J., Morgan, Noel G., Metz, Thomas O., Pasquali, Lorenzo, Eizirik, Décio L.
Published in Nature communications (22.05.2020)
Published in Nature communications (22.05.2020)
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Journal Article
C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase
Shields, Beverley M, McDonald, Timothy J, Oram, Richard, Hill, Anita, Hudson, Michelle, Leete, Pia, Pearson, Ewan R, Richardson, Sarah J, Morgan, Noel G, Hattersley, Andrew T
Published in Diabetes care (01.07.2018)
Published in Diabetes care (01.07.2018)
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Journal Article
Abnormal islet sphingolipid metabolism in type 1 diabetes
Holm, Laurits J., Krogvold, Lars, Hasselby, Jane P., Kaur, Simranjeet, Claessens, Laura A., Russell, Mark A., Mathews, Clayton E., Hanssen, Kristian F., Morgan, Noel G., Koeleman, Bobby P. C., Roep, Bart O., Gerling, Ivan C., Pociot, Flemming, Dahl-Jørgensen, Knut, Buschard, Karsten
Published in Diabetologia (01.07.2018)
Published in Diabetologia (01.07.2018)
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Journal Article
GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans
Stone, Virginia M., Dhayal, Shalinee, Brocklehurst, Katy J., Lenaghan, Carol, Sörhede Winzell, Maria, Hammar, Mårten, Xu, Xiufeng, Smith, David M., Morgan, Noel G.
Published in Diabetologia (01.06.2014)
Published in Diabetologia (01.06.2014)
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Journal Article
An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation
Saarimäki-Vire, Jonna, Balboa, Diego, Russell, Mark A., Saarikettu, Juha, Kinnunen, Matias, Keskitalo, Salla, Malhi, Amrinder, Valensisi, Cristina, Andrus, Colin, Eurola, Solja, Grym, Heli, Ustinov, Jarkko, Wartiovaara, Kirmo, Hawkins, R. David, Silvennoinen, Olli, Varjosalo, Markku, Morgan, Noel G., Otonkoski, Timo
Published in Cell reports (Cambridge) (11.04.2017)
Published in Cell reports (Cambridge) (11.04.2017)
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Journal Article
Developmentally dynamic changes in DNA methylation in the human pancreas
MacCalman, Ailsa, De Franco, Elisa, Franklin, Alice, Flaxman, Christine S, Richardson, Sarah J, Murrall, Kathryn, Burrage, Joe, Walker, Emma M, Morgan, Noel G, Hattersley, Andrew T, Dempster, Emma L, Hannon, Eilis, Jeffries, Aaron R, Owens, Nick D L, Mill, Jonathan
Published in BMC genomics (03.06.2024)
Published in BMC genomics (03.06.2024)
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Journal Article
Pancreatic Pathology in Type 1 Diabetes Mellitus
Richardson, Sarah J., Morgan, Noel G., Foulis, Alan K.
Published in Endocrine pathology (01.03.2014)
Published in Endocrine pathology (01.03.2014)
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Journal Article
The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120
Bjursell, Mikael, Xu, Xiufeng, Admyre, Therése, Böttcher, Gerhard, Lundin, Sofia, Nilsson, Ralf, Stone, Virginia M, Morgan, Noel G, Lam, Yan Y, Storlien, Leonard H, Lindén, Daniel, Smith, David M, Bohlooly-Y, Mohammad, Oscarsson, Jan
Published in PloS one (26.12.2014)
Published in PloS one (26.12.2014)
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Journal Article
Long-chain saturated fatty acid species are not toxic to human pancreatic β-cells and may offer protection against pro-inflammatory cytokine induced β-cell death
Thomas, Patricia, Leslie, Kaiyven A, Welters, Hannah J, Morgan, Noel G
Published in Nutrition & metabolism (12.01.2021)
Published in Nutrition & metabolism (12.01.2021)
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Journal Article
Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection
Chaffey, Jessica R., Young, Jay, Leslie, Kaiyven A., Partridge, Katie, Akhbari, Pouria, Dhayal, Shalinee, Hill, Jessica L., Wedgwood, Kyle C. A., Burnett, Edward, Russell, Mark A., Richardson, Sarah J., Morgan, Noel G.
Published in Scientific reports (02.08.2021)
Published in Scientific reports (02.08.2021)
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Journal Article
Type 1 Diabetes: Interferons and the Aftermath of Pancreatic Beta-Cell Enteroviral Infection
Akhbari, Pouria, Richardson, Sarah J, Morgan, Noel G
Published in Microorganisms (Basel) (15.09.2020)
Published in Microorganisms (Basel) (15.09.2020)
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Journal Article
Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion
Viloria, Katrina, Nasteska, Daniela, Briant, Linford J.B., Heising, Silke, Larner, Dean P., Fine, Nicholas H.F., Ashford, Fiona B., da Silva Xavier, Gabriela, Ramos, Maria Jiménez, Hasib, Annie, Cuozzo, Federica, Manning Fox, Jocelyn E., MacDonald, Patrick E., Akerman, Ildem, Lavery, Gareth G., Flaxman, Christine, Morgan, Noel G., Richardson, Sarah J., Hewison, Martin, Hodson, David J.
Published in Cell reports (Cambridge) (16.06.2020)
Published in Cell reports (Cambridge) (16.06.2020)
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Journal Article
Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study
Krogvold, Lars, Leete, Pia, Mynarek, Ida M, Russell, Mark A, Gerling, Ivan C, Lenchik, Nataliya I, Mathews, Clayton, Richardson, Sarah J, Morgan, Noel G, Dahl-Jørgensen, Knut
Published in Frontiers in endocrinology (Lausanne) (26.07.2022)
Published in Frontiers in endocrinology (Lausanne) (26.07.2022)
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Journal Article
Life and death decisions of the pancreatic β-cell : the role of fatty acids
NEWSHOLME, Philip, KEANE, Deirdre, WELTERS, Hannah J, MORGAN, Noel G
Published in Clinical science (1979) (2007)
Published in Clinical science (1979) (2007)
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Journal Article
Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells
Thomas, Patricia, Arden, Catherine, Corcoran, Jenna, Hacker, Christian, Welters, Hannah J., Morgan, Noel G.
Published in Nutrition & diabetes (20.04.2022)
Published in Nutrition & diabetes (20.04.2022)
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