Search Results - "Moretti, Loris" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Thieno[3,2‑b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure–Activity Relationship

Thieno[3,2‑b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure–Activity Relationship

by Vianello, Paola, Sartori, Luca, Amigoni, Federica, Cappa, Anna, Fagá, Giovanni, Fattori, Raimondo, Legnaghi, Elena, Ciossani, Giuseppe, Mattevi, Andrea, Meroni, Giuseppe, Moretti, Loris, Cecatiello, Valentina, Pasqualato, Sebastiano, Romussi, Alessia, Thaler, Florian, Trifiró, Paolo, Villa, Manuela, Botrugno, Oronza A, Dessanti, Paola, Minucci, Saverio, Vultaggio, Stefania, Zagarrí, Elisa, Varasi, Mario, Mercurio, Ciro
Published in Journal of medicinal chemistry (09.03.2017)

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Journal Article

Thieno[3,2‑b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration

Thieno[3,2‑b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration

by Sartori, Luca, Mercurio, Ciro, Amigoni, Federica, Cappa, Anna, Fagá, Giovanni, Fattori, Raimondo, Legnaghi, Elena, Ciossani, Giuseppe, Mattevi, Andrea, Meroni, Giuseppe, Moretti, Loris, Cecatiello, Valentina, Pasqualato, Sebastiano, Romussi, Alessia, Thaler, Florian, Trifiró, Paolo, Villa, Manuela, Vultaggio, Stefania, Botrugno, Oronza A, Dessanti, Paola, Minucci, Saverio, Zagarrí, Elisa, Carettoni, Daniele, Iuzzolino, Lucia, Varasi, Mario, Vianello, Paola
Published in Journal of medicinal chemistry (09.03.2017)

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Journal Article

Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models

Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models

by Romussi, Alessia, Cappa, Anna, Vianello, Paola, Brambillasca, Silvia, Cera, Maria Rosaria, Dal Zuffo, Roberto, Fagà, Giovanni, Fattori, Raimondo, Moretti, Loris, Trifirò, Paolo, Villa, Manuela, Vultaggio, Stefania, Cecatiello, Valentina, Pasqualato, Sebastiano, Dondio, Giulio, So, Chi Wai Eric, Minucci, Saverio, Sartori, Luca, Varasi, Mario, Mercurio, Ciro
Published in ACS medicinal chemistry letters (14.05.2020)

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Journal Article

ElectroShape: fast molecular similarity calculations incorporating shape, chirality and electrostatics

ElectroShape: fast molecular similarity calculations incorporating shape, chirality and electrostatics

by Armstrong, M. Stuart, Morris, Garrett M., Finn, Paul W., Sharma, Raman, Moretti, Loris, Cooper, Richard I., Richards, W. Graham
Published in Journal of computer-aided molecular design (01.09.2010)

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Journal Article

Characterization of compound 584, an Abl kinase inhibitor with lasting effects

Characterization of compound 584, an Abl kinase inhibitor with lasting effects

by Puttini, Miriam, Redaelli, Sara, Moretti, Loris, Brussolo, Stefania, Gunby, Rosalind H, Mologni, Luca, Marchesi, Edoardo, Cleris, Loredana, Donella-Deana, Arianna, Drueckes, Peter, Sala, Elisa, Lucchini, Vittorio, Kubbutat, Michael, Formelli, Franca, Zambon, Alfonso, Scapozza, Leonardo, Gambacorti-Passerini, Carlo
Published in Haematologica (Roma) (01.05.2008)

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Journal Article

Tyrosine kinase drug discovery: what can be learned from solved crystal structures?

Tyrosine kinase drug discovery: what can be learned from solved crystal structures?

by Moretti, Loris, Tchernin, Laura, Scapozza, Leonardo
Published in ARKIVOC (18.05.2006)

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Journal Article Web Resource

Software Infrastructure for Computer-aided Drug Discovery and Development, a Practical Example with Guidelines

Software Infrastructure for Computer-aided Drug Discovery and Development, a Practical Example with Guidelines

by Moretti, Loris, Sartori, Luca
Published in Molecular informatics (01.09.2016)

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Journal Article

A Simple and Resource-efficient Setup for the Computer-aided Drug Design Laboratory

A Simple and Resource-efficient Setup for the Computer-aided Drug Design Laboratory

by Moretti, Loris, Sartori, Luca
Published in Molecular informatics (01.10.2016)

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Journal Article

Discovery of NSD2‐Degraders from Novel and Selective DEL Hits

Discovery of NSD2‐Degraders from Novel and Selective DEL Hits

by LegaardAndersson, Jan, Christensen, Jesper, Kleine‐Kohlbrecher, Daniela, Vacher Comet, Itys, Fullerton Støier, Jonatan, Antoku, Yasuko, Poljak, Visnja, Moretti, Loris, Dolberg, Johannes, Jacso, Tomas, Jensby Nielsen, Søren, Nørregaard‐Madsen, Mads, Franch, Thomas, Helin, Kristian, Cloos, Paul A. C.
Published in Chembiochem : a European journal of chemical biology (14.12.2023)

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Journal Article

Cover Feature: Discovery of NSD2‐Degraders from Novel and Selective DEL Hits (ChemBioChem 24/2023)

Cover Feature: Discovery of NSD2‐Degraders from Novel and Selective DEL Hits (ChemBioChem 24/2023)

by LegaardAndersson, Jan, Christensen, Jesper, Kleine‐Kohlbrecher, Daniela, Vacher Comet, Itys, Fullerton Støier, Jonatan, Antoku, Yasuko, Poljak, Visnja, Moretti, Loris, Dolberg, Johannes, Jacso, Tomas, Jensby Nielsen, Søren, Nørregaard‐Madsen, Mads, Franch, Thomas, Helin, Kristian, Cloos, Paul A. C.
Published in Chembiochem : a European journal of chemical biology (14.12.2023)

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Journal Article

Synthesis, biological characterization and molecular modeling insights of spirochromanes as potent HDAC inhibitors

Synthesis, biological characterization and molecular modeling insights of spirochromanes as potent HDAC inhibitors

by Thaler, Florian, Moretti, Loris, Amici, Raffaella, Abate, Agnese, Colombo, Andrea, Carenzi, Giacomo, Fulco, Maria Carmela, Boggio, Roberto, Dondio, Giulio, Gagliardi, Stefania, Minucci, Saverio, Sartori, Luca, Varasi, Mario, Mercurio, Ciro
Published in European journal of medicinal chemistry (27.01.2016)

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Journal Article

Molecular alignment using multipole moments

Molecular alignment using multipole moments

by Moretti, Loris, Graham Richards, W.
Published in Bioorganic & medicinal chemistry letters (01.10.2010)

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Journal Article

Development of a Three-Dimensional Model for the N-Methyl-d-aspartate NR2A Subunit

Development of a Three-Dimensional Model for the N-Methyl-d-aspartate NR2A Subunit

by Grazioso, Giovanni, Moretti, Loris, Scapozza, Leonardo, De Amici, Marco, De Micheli, Carlo
Published in Journal of medicinal chemistry (25.08.2005)

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Journal Article

INDOLE DERIVATIVES AS HISTONE DEMETHYLASE INHIBITORS

INDOLE DERIVATIVES AS HISTONE DEMETHYLASE INHIBITORS

by VARASI, Mario, CAPPA, Anna, VIANELLO, Paola, MORETTI, Loris, SARTORI, Luca, MERCURIO, Ciro
Year of Publication 01.05.2024

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Patent

Model structures of the N-methyl- d-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands

Model structures of the N-methyl- d-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands

by Moretti, Loris, Pentikäinen, Olli T., Settimo, Luca, Johnson, Mark S.
Published in Journal of structural biology (01.03.2004)

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Journal Article

Indole derivatives as histone demethylase inhibitors

Indole derivatives as histone demethylase inhibitors

by VARASI, Mario, CAPPA, Anna, VIANELLO, Paola, MORETTI, Loris, SARTORI, Luca, MERCURIO, Ciro
Year of Publication 16.02.2023

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Patent

Scatola rigida, automontante, abbattibile, e procedimento per la sua realizzazione

Scatola rigida, automontante, abbattibile, e procedimento per la sua realizzazione

by Moretti, Loris
Year of Publication 11.05.2017

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Patent

THIENOPYRROLES AS HISTONE DEMETHYLASE INHIBITORS

THIENOPYRROLES AS HISTONE DEMETHYLASE INHIBITORS

by ZAGARRI, Elisa, VARASI, Mario, CAPPA, Anna, VIANELLO, Paola, MORETTI, Loris, VILLA, Manuela, SARTORI, Luca, MERCURIO, Ciro, ROMUSSI, Alessia, MERONI, Giuseppe
Year of Publication 22.02.2023

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Patent

System and machine for automatic closing of one-piece cardboard boxes, of the type composed of bottom and lid connected by a common side

System and machine for automatic closing of one-piece cardboard boxes, of the type composed of bottom and lid connected by a common side

by MORETTI, LORIS
Year of Publication 17.06.2009

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Patent

Indole derivatives as histone demethylase inhibitors

Indole derivatives as histone demethylase inhibitors

by Mercurio, Ciro, Varasi, Mario, Moretti, Loris, Vianello, Paola, Cappa, Anna, Sartori, Luca
Year of Publication 20.04.2021

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Patent