Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma
Orozco Morales, M Lizeth, Rinaldi, Catherine A, de Jong, Emma, Lansley, Sally M, Lee, Y C Gary, Zemek, Rachael M, Bosco, Anthony, Lake, Richard A, Lesterhuis, W Joost
Published in PloS one (05.05.2023)
Published in PloS one (05.05.2023)
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Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner
Tilsed, Caitlin M, Morales, M Lizeth Orozco, Zemek, Rachael M, Gordon, Brianna A, Piggott, Matthew J, Nowak, Anna K, Fisher, Scott A, Lake, Richard A, Lesterhuis, W Joost
Published in BMC cancer (13.02.2024)
Published in BMC cancer (13.02.2024)
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Local therapy with combination TLR agonists stimulates systemic anti-tumor immunity and sensitizes tumors to immune checkpoint blockade
Rwandamuriye, Francois Xavier, Wang, Tao, Zhang, Hanfu, Elaskalani, Omar, Kuster, Jorren, Ye, Xueting, Vitali, Breana, Schreurs, Juliët, Orozco Morales, M Lizeth, Norret, Marck, Evans, Cameron W, Zemek, Rachael M, Iyer, K Swaminathan, Lesterhuis, W Joost, Wylie, Ben
Published in Oncoimmunology (2024)
Published in Oncoimmunology (2024)
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PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective
Orozco Morales, M. Lizeth, Rinaldi, Catherine A., de Jong, Emma, Lansley, Sally M., Gummer, Joel P.A., Olasz, Bence, Nambiar, Shabarinath, Hope, Danika E., Casey, Thomas H., Lee, Y. C. Gary, Leslie, Connull, Nealon, Gareth, Shackleford, David M., Powell, Andrew K., Grimaldi, Marina, Balaguer, Patrick, Zemek, Rachael M., Bosco, Anthony, Piggott, Matthew J., Vrielink, Alice, Lake, Richard A., Lesterhuis, W. Joost
Published in iScience (21.01.2022)
Published in iScience (21.01.2022)
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Anti-metabolite chemotherapy increases LAG-3 expressing tumor-infiltrating lymphocytes which can be targeted by combination immune checkpoint blockade
Principe, Nicola, Phung, Amber-Lee, Stevens, Kofi L P, Elaskalani, Omar, Wylie, Ben, Tilsed, Caitlin M, Sheikh, Fezaan, Orozco Morales, M Lizeth, Kidman, Joel, Marcq, Elly, Fisher, Scott A, Nowak, Anna K, McDonnell, Alison M, Lesterhuis, W Joost, Chee, Jonathan
Published in Journal for immunotherapy of cancer (28.09.2024)
Published in Journal for immunotherapy of cancer (28.09.2024)
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CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy
Tilsed, Caitlin M., Principe, Nicola, Kidman, Joel, Chin, Wee Loong, Orozco Morales, M. Lizeth, Zemek, Rachael M., Chee, Jonathan, Islam, Rasa, Fear, Vanessa S., Forbes, Catherine, Aston, Wayne J., Jansen, Maud, Chopra, Abha, Lassmann, Timo, Nowak, Anna K., Fisher, Scott A., Lake, Richard A., Lesterhuis, W. Joost
Published in Cell reports (Cambridge) (27.12.2022)
Published in Cell reports (Cambridge) (27.12.2022)
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