Bone marrow characterization in sickle cell disease: inflammation and stress erythropoiesis lead to suboptimal CD34 recovery
Leonard, Alexis, Bonifacino, Aylin, Dominical, Venina M., Luo, Min, Haro‐Mora, Juan J., Demirci, Selami, Uchida, Naoya, Pierciey, Francis J., Tisdale, John F.
Published in British journal of haematology (01.07.2019)
Published in British journal of haematology (01.07.2019)
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Journal Article
Efficient Generation of β‐Globin‐Expressing Erythroid Cells Using Stromal Cell‐Derived Induced Pluripotent Stem Cells from Patients with Sickle Cell Disease
Uchida, Naoya, Haro‐Mora, Juan J., Fujita, Atsushi, Lee, Duck‐Yeon, Winkler, Thomas, Hsieh, Matthew M., Tisdale, John F.
Published in Stem cells (Dayton, Ohio) (01.03.2017)
Published in Stem cells (Dayton, Ohio) (01.03.2017)
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Journal Article
Biallelic correction of sickle cell disease‐derived induced pluripotent stem cells (iPSCs) confirmed at the protein level through serum‐free iPS‐sac/erythroid differentiation
Haro‐Mora, Juan J., Uchida, Naoya, Demirci, Selami, Wang, Qi, Zou, Jizhong, Tisdale, John F.
Published in Stem cells translational medicine (01.05.2020)
Published in Stem cells translational medicine (01.05.2020)
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Journal Article
Low-Dose Busulfan Reduces Human CD34+ Cell Doses Required for Engraftment in c-kit Mutant Immunodeficient Mice
Leonard, Alexis, Yapundich, Morgan, Nassehi, Tina, Gamer, Jackson, Drysdale, Claire M., Haro-Mora, Juan J., Demirci, Selami, Hsieh, Matthew M., Uchida, Naoya, Tisdale, John F.
Published in Molecular therapy. Methods & clinical development (13.12.2019)
Published in Molecular therapy. Methods & clinical development (13.12.2019)
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Journal Article
Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders
Uchida, Naoya, Hsieh, Matthew M, Raines, Lydia, Haro-Mora, Juan J, Demirci, Selami, Bonifacino, Aylin C, Krouse, Allen E, Metzger, Mark E, Donahue, Robert E, Tisdale, John F
Published in Nature communications (02.10.2019)
Published in Nature communications (02.10.2019)
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Journal Article
FNDC5 could be regulated by leptin in adipose tissue
Gutierrez-Repiso, Carolina, Garcia-Serrano, Sara, Rodriguez-Pacheco, Francisca, Garcia-Escobar, Eva, Haro-Mora, Juan J., Garcia-Arnes, Juan, Valdes, Sergio, Gonzalo, Montserrat, Soriguer, Federico, Moreno-Ruiz, Francisco J., Rodriguez-Cañete, Alberto, Martinez-Ferriz, Abelardo, Santoyo, Julio S., Perez-Valero, Vidal, Garcia-Fuentes, Eduardo
Published in European journal of clinical investigation (01.10.2014)
Published in European journal of clinical investigation (01.10.2014)
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Journal Article
Cas9 protein delivery non-integrating lentiviral vectors for gene correction in sickle cell disease
Uchida, Naoya, Drysdale, Claire M., Nassehi, Tina, Gamer, Jackson, Yapundich, Morgan, DiNicola, Julia, Shibata, Yoshitaka, Hinds, Malikiya, Gudmundsdottir, Bjorg, Haro-Mora, Juan J., Demirci, Selami, Tisdale, John F.
Published in Molecular therapy. Methods & clinical development (11.06.2021)
Published in Molecular therapy. Methods & clinical development (11.06.2021)
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Journal Article
Effect of GLP-1 Treatment on Bone Turnover in Normal, Type 2 Diabetic, and Insulin-Resistant States
Nuche-Berenguer, Bernardo, Moreno, Paola, Esbrit, Pedro, Dapía, Sonia, Caeiro, José R., Cancelas, Jesús, Haro-Mora, Juan J., Villanueva-Peñacarrillo, María L.
Published in Calcified tissue international (01.06.2009)
Published in Calcified tissue international (01.06.2009)
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Journal Article
High-Efficiency Lentiviral Transduction of Human CD34+ Cells in High-Density Culture with Poloxamer and Prostaglandin E2
Uchida, Naoya, Nassehi, Tina, Drysdale, Claire M., Gamer, Jackson, Yapundich, Morgan, Demirci, Selami, Haro-Mora, Juan J., Leonard, Alexis, Hsieh, Matthew M., Tisdale, John F.
Published in Molecular therapy. Methods & clinical development (14.06.2019)
Published in Molecular therapy. Methods & clinical development (14.06.2019)
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Journal Article
βT87Q-Globin Gene Therapy Reduces Sickle Hemoglobin Production, Allowing for Ex Vivo Anti-sickling Activity in Human Erythroid Cells
Demirci, Selami, Gudmundsdottir, Bjorg, Li, Quan, Haro-Mora, Juan J., Nassehi, Tina, Drysdale, Claire, Yapundich, Morgan, Gamer, Jackson, Seifuddin, Fayaz, Tisdale, John F., Uchida, Naoya
Published in Molecular therapy. Methods & clinical development (12.06.2020)
Published in Molecular therapy. Methods & clinical development (12.06.2020)
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Journal Article
Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation
Demirci, Selami, Haro-Mora, Juan J, Leonard, Alexis, Drysdale, Claire, Malide, Daniela, Keyvanfar, Keyvan, Essawi, Khaled, Vizcardo, Raul, Tamaoki, Naritaka, Restifo, Nicholas P, Tisdale, John F, Uchida, Naoya
Published in Stem cell research & therapy (17.12.2020)
Published in Stem cell research & therapy (17.12.2020)
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Journal Article
Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models
Uchida, Naoya, Li, Linhong, Nassehi, Tina, Drysdale, Claire M., Yapundich, Morgan, Gamer, Jackson, Haro-Mora, Juan J., Demirci, Selami, Leonard, Alexis, Bonifacino, Aylin C., Krouse, Allen E., Linde, N. Seth, Allen, Cornell, Peshwa, Madhusudan V., De Ravin, Suk See, Donahue, Robert E., Malech, Harry L., Tisdale, John F.
Published in Cell reports. Medicine (20.04.2021)
Published in Cell reports. Medicine (20.04.2021)
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Journal Article
Serum-free Erythroid Differentiation for Efficient Genetic Modification and High-Level Adult Hemoglobin Production
Uchida, Naoya, Demirci, Selami, Haro-Mora, Juan J, Fujita, Atsushi, Raines, Lydia N, Hsieh, Matthew M, Tisdale, John F
Published in Molecular therapy. Methods & clinical development (15.06.2018)
Published in Molecular therapy. Methods & clinical development (15.06.2018)
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Journal Article
BCL11A enhancer-edited hematopoietic stem cells persist in rhesus monkeys without toxicity
Demirci, Selami, Zeng, Jing, Wu, Yuxuan, Uchida, Naoya, Shen, Anne H, Pellin, Danilo, Gamer, Jackson, Yapundich, Morgan, Drysdale, Claire, Bonanno, Jasmine, Bonifacino, Aylin C, Krouse, Allen E, Linde, Nathaniel S, Engels, Theresa, Donahue, Robert E, Haro-Mora, Juan J, Leonard, Alexis, Nassehi, Tina, Luk, Kevin, Porter, Shaina N, Lazzarotto, Cicera R, Tsai, Shengdar Q, Weiss, Mitchell J, Pruett-Miller, Shondra M, Wolfe, Scot A, Bauer, Daniel E, Tisdale, John F
Published in The Journal of clinical investigation (01.12.2020)
Published in The Journal of clinical investigation (01.12.2020)
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Journal Article
Effect of insulin analogues on 3t3-l1 adipogenesis and lipolysis
García-Escobar, Eva, Rodríguez-Pacheco, Francisca, Haro-Mora, Juan J., Gomez-Zumaquero, Juan M., Rubio-Martín, Elehazara, Gutierrez-Repiso, Carolina, Soriguer, Federico, Rojo-Martínez, Gemma
Published in European journal of clinical investigation (01.09.2011)
Published in European journal of clinical investigation (01.09.2011)
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Journal Article
Ovarian steroids and cancer: news on the breast, questions on the reproductive tract
Hidalgo-Mora, Juan J., Tarín, Juan J., Cano, Antonio
Published in Gynecological endocrinology (04.05.2021)
Published in Gynecological endocrinology (04.05.2021)
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Journal Article
High-level embryonic globin production with efficient erythroid differentiation from a K562 erythroleukemia cell line
Uchida, Naoya, Haro-Mora, Juan J., Demirci, Selami, Fujita, Atsushi, Raines, Lydia, Hsieh, Matthew M., Tisdale, John F.
Published in Experimental hematology (01.06.2018)
Published in Experimental hematology (01.06.2018)
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Journal Article