Autotaxin facilitates selective LPA receptor signaling
Salgado-Polo, Fernando, Borza, Razvan, Matsoukas, Minos-Timotheos, Marsais, Florence, Jagerschmidt, Catherine, Waeckel, Ludovic, Moolenaar, Wouter H., Ford, Paul, Heckmann, Bertrand, Perrakis, Anastassis
Published in Cell chemical biology (19.01.2023)
Published in Cell chemical biology (19.01.2023)
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Autotaxin determines colitis severity in mice and is secreted by B cells in the colon
Lin, Songbai, Haque, Abedul, Raeman, Reben, Guo, Leilei, He, Peijian, Denning, Timothy L, El-Rayes, Bassel, Moolenaar, Wouter H, Yun, C Chris
Published in The FASEB journal (01.03.2019)
Published in The FASEB journal (01.03.2019)
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Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
Matas-Rico, Elisa, Frijlink, Elselien, van der Haar Àvila, Irene, Menegakis, Apostolos, van Zon, Maaike, Morris, Andrew J., Koster, Jan, Salgado-Polo, Fernando, de Kivit, Sander, Lança, Telma, Mazzocca, Antonio, Johnson, Zoë, Haanen, John, Schumacher, Ton N., Perrakis, Anastassis, Verbrugge, Inge, van den Berg, Joost H., Borst, Jannie, Moolenaar, Wouter H.
Published in Cell reports (Cambridge) (16.11.2021)
Published in Cell reports (Cambridge) (16.11.2021)
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Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis
Chattopadhyay, Arnab, Mukherjee, Pallavi, Sulaiman, Dawoud, Wang, Huan, Girjalva, Victor, Dorreh, Nasrin, Jacobs, Jonathan P., Delk, Samuel, Moolenaar, Wouter H., Navab, Mohamad, Reddy, Srinivasa T., Fogelman, Alan M.
Published in Journal of lipid research (01.05.2023)
Published in Journal of lipid research (01.05.2023)
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Structure of NPP1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification
Jansen, Silvia, Perrakis, Anastassis, Ulens, Chris, Winkler, Claudia, Andries, Maria, Joosten, Robbie P., Van Acker, Maarten, Luyten, Frank P., Moolenaar, Wouter H., Bollen, Mathieu
Published in Structure (London) (07.11.2012)
Published in Structure (London) (07.11.2012)
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Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid
Dusaulcy, Rodolphe, Rancoule, Chloé, Grès, Sandra, Wanecq, Estelle, Colom, André, Guigné, Charlotte, van Meeteren, Laurens A., Moolenaar, Wouter H., Valet, Philippe, Saulnier-Blache, Jean Sébastien
Published in Journal of lipid research (01.06.2011)
Published in Journal of lipid research (01.06.2011)
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Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling
Keune, Willem-Jan, Hausmann, Jens, Bolier, Ruth, Tolenaars, Dagmar, Kremer, Andreas, Heidebrecht, Tatjana, Joosten, Robbie P., Sunkara, Manjula, Morris, Andrew J., Matas-Rico, Elisa, Moolenaar, Wouter H., Oude Elferink, Ronald P., Perrakis, Anastassis
Published in Nature communications (14.04.2016)
Published in Nature communications (14.04.2016)
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Lysophosphatidic acid is a potential mediator of cholestatic pruritus
Kremer, Andreas E, Martens, Job J W W, Kulik, Wim, Ruëff, Franziska, Kuiper, Edith M M, van Buuren, Henk R, van Erpecum, Karel J, Kondrackiene, Jurate, Prieto, Jesus, Rust, Christian, Geenes, Victoria L, Williamson, Catherine, Moolenaar, Wouter H, Beuers, Ulrich, Oude Elferink, Ronald P J
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2010)
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Structural basis of substrate discrimination and integrin binding by autotaxin
Morris, Andrew J, Moolenaar, Wouter H, Perrakis, Anastassis, Hausmann, Jens, Kamtekar, Satwik, Christodoulou, Evangelos, Day, Jacqueline E, Wu, Tao, Fulkerson, Zachary, Albers, Harald M H G, van Meeteren, Laurens A, Houben, Anna J S, van Zeijl, Leonie, Jansen, Silvia, Andries, Maria, Hall, Troii, Pegg, Lyle E, Benson, Timothy E, Kasiem, Mobien, Harlos, Karl, Kooi, Craig W Vander, Smyth, Susan S, Ovaa, Huib, Bollen, Mathieu
Published in Nature structural & molecular biology (01.02.2011)
Published in Nature structural & molecular biology (01.02.2011)
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Autotaxin, a Secreted Lysophospholipase D, Is Essential for Blood Vessel Formation during Development
van Meeteren, Laurens A., Ruurs, Paula, Stortelers, Catelijne, Bouwman, Peter, van Rooijen, Marga A., Pradère, Jean Philippe, Pettit, Trevor R., Wakelam, Michael J. O., Saulnier-Blache, Jean Sébastien, Mummery, Christine L., Moolenaar, Wouter H., Jonkers, Jos
Published in Molecular and Cellular Biology (01.07.2006)
Published in Molecular and Cellular Biology (01.07.2006)
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Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation
Albers, Harald M.H.G, Dong, Anping, van Meeteren, Laurens A, Egan, David A, Sunkara, Manjula, van Tilburg, Erica W, Schuurman, Karianne, van Tellingen, Olaf, Morris, Andrew J, Smyth, Susan S, Moolenaar, Wouter H, Ovaa, Huib
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2010)
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Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation
Salgado-Polo, Fernando, van Veen, Michiel, van den Broek, Bram, Jalink, Kees, Leyton-Puig, Daniela, Perrakis, Anastassis, Moolenaar, Wouter H, Matas-Rico, Elisa
Published in Journal of cell science (01.02.2020)
Published in Journal of cell science (01.02.2020)
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Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome
Matas-Rico, Elisa, van Veen, Michiel, Leyton-Puig, Daniela, van den Berg, Jeroen, Koster, Jan, Kedziora, Katarzyna M., Molenaar, Bas, Weerts, Marjolein J.A., de Rink, Iris, Medema, René H., Giepmans, Ben N.G., Perrakis, Anastassis, Jalink, Kees, Versteeg, Rogier, Moolenaar, Wouter H.
Published in Cancer cell (10.10.2016)
Published in Cancer cell (10.10.2016)
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