Cellular dormancy in minimal residual disease following targeted therapy
Ruth, Jason R, Pant, Dhruv K, Pan, Tien-Chi, Seidel, Hans E, Baksh, Sanjeethan C, Keister, Blaine A, Singh, Rita, Sterner, Christopher J, Bakewell, Suzanne J, Moody, Susan E, Belka, George K, Chodosh, Lewis A
Published in Breast cancer research : BCR (04.06.2021)
Published in Breast cancer research : BCR (04.06.2021)
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Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit
Zhu, Zehua, Aref, Amir R, Cohoon, Travis J, Barbie, Thanh U, Imamura, Yu, Yang, Shenghong, Moody, Susan E, Shen, Rhine R, Schinzel, Anna C, Thai, Tran C, Reibel, Jacob B, Tamayo, Pablo, Godfrey, Jason T, Qian, Zhi Rong, Page, Asher N, Maciag, Karolina, Chan, Edmond M, Silkworth, Whitney, Labowsky, Mary T, Rozhansky, Lior, Mesirov, Jill P, Gillanders, William E, Ogino, Shuji, Hacohen, Nir, Gaudet, Suzanne, Eck, Michael J, Engelman, Jeffrey A, Corcoran, Ryan B, Wong, Kwok-Kin, Hahn, William C, Barbie, David A
Published in Cancer discovery (01.04.2014)
Published in Cancer discovery (01.04.2014)
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The transcriptional repressor Snail promotes mammary tumor recurrence
Moody, Susan E., Perez, Denise, Pan, Tien-chi, Sarkisian, Christopher J., Portocarrero, Carla P., Sterner, Christopher J., Notorfrancesco, Kathleen L., Cardiff, Robert D., Chodosh, Lewis A.
Published in Cancer cell (01.09.2005)
Published in Cancer cell (01.09.2005)
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Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers
Raeder, Maria B, Birkeland, Even, Trovik, Jone, Krakstad, Camilla, Shehata, Shyemaa, Schumacher, Steven, Zack, Travis I, Krohn, Antje, Werner, Henrica Mj, Moody, Susan E, Wik, Elisabeth, Stefansson, Ingunn M, Holst, Frederik, Oyan, Anne M, Tamayo, Pablo, Mesirov, Jill P, Kalland, Karl H, Akslen, Lars A, Simon, Ronald, Beroukhim, Rameen, Salvesen, Helga B
Published in PloS one (05.02.2013)
Published in PloS one (05.02.2013)
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Journal Article
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
Moody, Susan E, Sarkisian, Christopher J, Hahn, Kristina T, Gunther, Edward J, Pickup, Steven, Dugan, Katherine D, Innocent, Nathalie, Cardiff, Robert D, Schnall, Mitchell D, Chodosh, Lewis A
Published in Cancer cell (01.12.2002)
Published in Cancer cell (01.12.2002)
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Journal Article
Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
Gunther, Edward J, Moody, Susan E, Belka, George K, Hahn, Kristina T, Innocent, Nathalie, Dugan, Katherine D, Cardiff, Robert D, Chodosh, Lewis A
Published in Genes & development (15.02.2003)
Published in Genes & development (15.02.2003)
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c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
Chodosh, Lewis A, D'Cruz, Celina M, Gunther, Edward J, Boxer, Robert B, Hartman, Jennifer L, Sintasath, Louis, Moody, Susan E, Cox, James D, Ha, Seung I, Belka, George K, Golant, Alexander, Cardiff, Robert D
Published in Nature medicine (01.02.2001)
Published in Nature medicine (01.02.2001)
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Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling
Liu, Chen, Lu, Hengyu, Wang, Hongyun, Loo, Alice, Zhang, Xiamei, Yang, Guizhi, Kowal, Colleen, Delach, Scott, Wang, Ye, Goldoni, Silvia, Hastings, William D, Wong, Karrie, Gao, Hui, Meyer, Matthew J, Moody, Susan E, LaMarche, Matthew J, Engelman, Jeffrey A, Williams, Juliet A, Hammerman, Peter S, Abrams, Tinya J, Mohseni, Morvarid, Caponigro, Giordano, Hao, Huai-Xiang
Published in Clinical cancer research (01.01.2021)
Published in Clinical cancer research (01.01.2021)
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Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours
Rodon, Jordi, Argilés, Guillem, Connolly, Roisin M., Vaishampayan, Ulka, de Jonge, Maja, Garralda, Elena, Giannakis, Marios, Smith, David C., Dobson, Jason R., McLaughlin, Margaret E., Seroutou, Abdelkader, Ji, Yan, Morawiak, Jennifer, Moody, Susan E., Janku, Filip
Published in British journal of cancer (06.07.2021)
Published in British journal of cancer (06.07.2021)
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Persistent Parity-Induced Changes in Growth Factors, TGF-β3, and Differentiation in the Rodent Mammary Gland
D’Cruz, Celina M, Moody, Susan E, Master, Stephen R, Hartman, Jennifer L, Keiper, Elizabeth A, Imielinski, Marcin B, Cox, James D, Wang, James Y, Ha, Seung I, Keister, Blaine A, Chodosh, Lewis A
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2002)
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2002)
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SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors
Lu, Hengyu, Liu, Chen, Velazquez, Roberto, Wang, Hongyun, Dunkl, Lukas Manuel, Kazic-Legueux, Malika, Haberkorn, Anne, Billy, Eric, Manchado, Eusebio, Brachmann, Saskia M, Moody, Susan E, Engelman, Jeffrey A, Hammerman, Peter S, Caponigro, Giordano, Mohseni, Morvarid, Hao, Huai-Xiang
Published in Molecular cancer therapeutics (01.07.2019)
Published in Molecular cancer therapeutics (01.07.2019)
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Systematic RNA interference reveals that oncogenic KRAS -driven cancers require TBK1
Kim, So Young, Sabatini, David M, Michel, Kathrin, Tamayo, Pablo, Weir, Barbara A, Le, Hanh, Mermel, Craig, Gupta, Piyush B, Meyerson, Matthew, Hahn, William C, Schinzel, Anna C, Hoersch, Sebastian, Lander, Eric S, Sandy, Peter, Mesirov, Jill P, Sheng, Qing, Boehm, Jesse S, Meylan, Etienne, Gilliland, D. Gary, Barbie, David A, Sos, Martin L, Fröhling, Stefan, Chan, Edmond M, Wittner, Ben S, Ramaswamy, Sridhar, Livingston, David M, Root, David E, Reiling, Jan H, Wadlow, Raymond C, Dunn, Ian F, Thomas, Roman K, Scholl, Claudia, Moody, Susan E, Silver, Serena J, Jacks, Tyler
Published in Nature (London) (05.11.2009)
Published in Nature (London) (05.11.2009)
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Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study
Tan, Daniel S-W, Leighl, Natasha B, Riely, Gregory J, Yang, James C-H, Sequist, Lecia V, Wolf, Juergen, Seto, Takashi, Felip, Enriqueta, Aix, Santiago P, Jonnaert, Maud, Pan, Chun, Tan, Eugene Y, Ko, Jinnie, Moody, Susan E, Kim, Dong-Wan
Published in The lancet respiratory medicine (01.06.2020)
Published in The lancet respiratory medicine (01.06.2020)
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PIK3CA mutant tumors depend on oxoglutarate dehydrogenase
Ilic, Nina, Birsoy, Kıvanç, Aguirre, Andrew J., Kory, Nora, Pacold, Michael E., Singh, Shambhavi, Moody, Susan E., DeAngelo, Joseph D., Spardy, Nicole A., Freinkman, Elizaveta, Weir, Barbara A., Tsherniak, Aviad, Cowley, Glenn S., Root, David E., Asara, John M., Vazquez, Francisca, Widlund, Hans R., Sabatini, David M., Hahn, William C.
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2017)
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CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors
Wang, Jiawan, Calizo, Ana, Zhang, Lindy, Pino, James C, Lyu, Yang, Pollard, Kai, Zhang, Xiaochun, Larsson, Alex T, Conniff, Eric, Llosa, Nicolas J, Wood, David K, Largaespada, David A, Moody, Susan E, Gosline, Sara J, Hirbe, Angela C, Pratilas, Christine A
Published in Science advances (24.11.2023)
Published in Science advances (24.11.2023)
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Conditional overexpression of active transforming growth factor β1 in vivo accelerates metastases of transgenic mammary tumors
MURAOKA-COOK, Rebecca S, KUROKAWA, Hirokazu, KOH, Yasuhiro, FORBES, James T, ROEBUCK, L. Renee, BARCELLOS-HOFF, Mary Helen, MOODY, Susan E, CHODOSH, Lewis A, ARTEAGA, Carlos L
Published in Cancer research (Chicago, Ill.) (15.12.2004)
Published in Cancer research (Chicago, Ill.) (15.12.2004)
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Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy
BLAKELY, Collin M, STODDARD, Alexander J, BELKA, George K, DUGAN, Katherine D, NOTARFRANCESCO, Kathleen L, MOODY, Susan E, D'CRUZ, Celina M, CHODOSH, Lewis A
Published in Cancer research (Chicago, Ill.) (15.06.2006)
Published in Cancer research (Chicago, Ill.) (15.06.2006)
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