Microtubule-Targeting Drugs: More than Antimitotics
Kaul, Roma, Risinger, April L, Mooberry, Susan L
Published in Journal of natural products (Washington, D.C.) (22.03.2019)
Published in Journal of natural products (Washington, D.C.) (22.03.2019)
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Eribulin mesylate: mechanism of action of a unique microtubule-targeting agent
Dybdal-Hargreaves, Nicholas F, Risinger, April L, Mooberry, Susan L
Published in Clinical cancer research (01.06.2015)
Published in Clinical cancer research (01.06.2015)
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Microtubule dynamics as a target in oncology
Risinger, April L, Giles, Francis J, Mooberry, Susan L
Published in Cancer treatment reviews (01.05.2009)
Published in Cancer treatment reviews (01.05.2009)
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Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer
Choudhary, Shruti, Doshi, Arpit, Luckett-Chastain, Lerin, Ihnat, Michael, Hamel, Ernest, Mooberry, Susan L., Gangjee, Aleem
Published in Bioorganic & medicinal chemistry (01.04.2021)
Published in Bioorganic & medicinal chemistry (01.04.2021)
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Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent
Xiang, Weiguo, Choudhary, Shruti, Hamel, Ernest, Mooberry, Susan L., Gangjee, Aleem
Published in Bioorganic & medicinal chemistry (15.05.2018)
Published in Bioorganic & medicinal chemistry (15.05.2018)
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Crowdsourcing Natural Products Discovery to Access Uncharted Dimensions of Fungal Metabolite Diversity
Du, Lin, Robles, Andrew J., King, Jarrod B., Powell, Douglas R., Miller, Andrew N., Mooberry, Susan L., Cichewicz, Robert H.
Published in Angewandte Chemie (International ed.) (13.01.2014)
Published in Angewandte Chemie (International ed.) (13.01.2014)
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Design, synthesis and preclinical evaluation of 5-methyl-N-4-aryl-furo [2,3-d] pyrimidines as single agents with combination chemotherapy potential
Devambatla, Ravi Kumar Vyas, Choudhary, Shruti, Ihnat, Michael, Hamel, Ernest, Mooberry, Susan L., Gangjee, Aleem
Published in Bioorganic & medicinal chemistry letters (01.10.2018)
Published in Bioorganic & medicinal chemistry letters (01.10.2018)
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Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands
Balaguer, Francisco de Asís, Mühlethaler, Tobias, Estévez-Gallego, Juan, Calvo, Enrique, Giménez-Abián, Juan Francisco, Risinger, April L, Sorensen, Erik J, Vanderwal, Christopher D, Altmann, Karl-Heinz, Mooberry, Susan L, Steinmetz, Michel O, Oliva, María Ángela, Prota, Andrea E, Díaz, J Fernando
Published in International journal of molecular sciences (20.03.2019)
Published in International journal of molecular sciences (20.03.2019)
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Journal Article
Taccalonolide microtubule stabilizers
Li, Jing, Risinger, April L., Mooberry, Susan L.
Published in Bioorganic & medicinal chemistry (15.09.2014)
Published in Bioorganic & medicinal chemistry (15.09.2014)
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Journal Article
Structure–Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells
Robles, Andrew J, McCowen, Shelby, Cai, Shengxin, Glassman, Michaels, Ruiz, Francisco, Cichewicz, Robert H, McHardy, Stanton F, Mooberry, Susan L
Published in Journal of medicinal chemistry (22.11.2017)
Published in Journal of medicinal chemistry (22.11.2017)
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The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents
Zhang, Xin, Raghavan, Sudhir, Ihnat, Michael, Hamel, Ernest, Zammiello, Cynthia, Bastian, Anja, Mooberry, Susan L., Gangjee, Aleem
Published in Bioorganic & medicinal chemistry (15.05.2015)
Published in Bioorganic & medicinal chemistry (15.05.2015)
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Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3- d ]pyrimidines as Microtubule Targeting Agents
Islam, Farhana, Doshi, Arpit, Robles, Andrew J, Quadery, Tasdique M, Zhang, Xin, Zhou, Xilin, Hamel, Ernest, Mooberry, Susan L, Gangjee, Aleem
Published in Molecules (Basel, Switzerland) (01.01.2022)
Published in Molecules (Basel, Switzerland) (01.01.2022)
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Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer
Robles, Andrew J, Du, Lin, Cichewicz, Robert H, Mooberry, Susan L
Published in Journal of natural products (Washington, D.C.) (22.07.2016)
Published in Journal of natural products (Washington, D.C.) (22.07.2016)
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