Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity
Wright, Gabriela, Golubeva, Volha, Remsing Rix, Lily L, Berndt, Norbert, Luo, Yunting, Ward, Grace A, Gray, Jhanelle E, Schonbrunn, Ernst, Lawrence, Harshani R, Monteiro, Alvaro N.A, Rix, Uwe
Published in ACS chemical biology (21.07.2017)
Published in ACS chemical biology (21.07.2017)
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Principles for the post-GWAS functional characterization of cancer risk loci
Freedman, Matthew L, Monteiro, Alvaro N A, Gayther, Simon A, Coetzee, Gerhard A, Risch, Angela, Plass, Christoph, Casey, Graham, De Biasi, Mariella, Carlson, Chris, Duggan, David, James, Michael, Liu, Pengyuan, Tichelaar, Jay W, Vikis, Haris G, You, Ming, Mills, Ian G
Published in Nature genetics (01.06.2011)
Published in Nature genetics (01.06.2011)
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Journal Article
Strong functional data for pathogenicity or neutrality classify BRCA2 DNA-binding-domain variants of uncertain significance
Richardson, Marcy E., Hu, Chunling, Lee, Kun Y., LaDuca, Holly, Fulk, Kelly, Durda, Kate M., Deckman, Ashley M., Goldgar, David E., Monteiro, Alvaro N.A., Gnanaolivu, Rohan, Hart, Steven N., Polley, Eric C., Chao, Elizabeth, Pesaran, Tina, Couch, Fergus J.
Published in American journal of human genetics (04.03.2021)
Published in American journal of human genetics (04.03.2021)
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Journal Article
Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches
Guidugli, Lucia, Shimelis, Hermela, Masica, David L., Pankratz, Vernon S., Lipton, Gary B., Singh, Namit, Hu, Chunling, Monteiro, Alvaro N.A., Lindor, Noralane M., Goldgar, David E., Karchin, Rachel, Iversen, Edwin S., Couch, Fergus J.
Published in American journal of human genetics (01.02.2018)
Published in American journal of human genetics (01.02.2018)
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Journal Article
Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models
Hart, Steven N., Hoskin, Tanya, Shimelis, Hermela, Moore, Raymond M., Feng, Bingjian, Thomas, Abigail, Lindor, Noralane M., Polley, Eric C., Goldgar, David E., Iversen, Edwin, Monteiro, Alvaro N.A., Suman, Vera J., Couch, Fergus J.
Published in Genetics in medicine (01.01.2019)
Published in Genetics in medicine (01.01.2019)
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Journal Article
A Systematic Genetic Assessment of 1,433 Sequence Variants of Unknown Clinical Significance in the BRCA1 and BRCA2 Breast Cancer–Predisposition Genes
Easton, Douglas F., Deffenbaugh, Amie M., Pruss, Dmitry, Frye, Cynthia, Wenstrup, Richard J., Allen-Brady, Kristina, Tavtigian, Sean V., Monteiro, Alvaro N.A., Iversen, Edwin S., Couch, Fergus J., Goldgar, David E.
Published in American journal of human genetics (01.11.2007)
Published in American journal of human genetics (01.11.2007)
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Journal Article
Comprehensive Analysis of Missense Variations in the BRCT Domain of BRCA1 by Structural and Functional Assays
LEE, Megan S, GREEN, Ruth, GLOVER, J. N. Mark, MARSILLAC, Sylvia M, COQUELLE, Nicolas, WILLIAMS, R. Scott, YEUNG, Telford, FOO, Desmond, DUONG HAU, D, BEN HUI, MONTEIRO, Alvaro N. A
Published in Cancer research (Chicago, Ill.) (15.06.2010)
Published in Cancer research (Chicago, Ill.) (15.06.2010)
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Journal Article
Assessment of functional effects of unclassified genetic variants
Couch, Fergus J, Rasmussen, Lene Juel, Hofstra, Robert, Monteiro, Alvaro N.A, Greenblatt, Marc S, de Wind, Niels
Published in Human mutation (01.11.2008)
Published in Human mutation (01.11.2008)
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Journal Article
Integrated Evaluation of DNA Sequence Variants of Unknown Clinical Significance: Application to BRCA1 and BRCA2
Goldgar, David E., Easton, Douglas F., Deffenbaugh, Amie M., Monteiro, Alvaro N.A., Tavtigian, Sean V., Couch, Fergus J.
Published in American journal of human genetics (01.10.2004)
Published in American journal of human genetics (01.10.2004)
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Journal Article
BRCT domains: A little more than kin, and less than kind
Gerloff, Dietlind L., Woods, Nicholas T., Farago, April A., Monteiro, Alvaro N.A.
Published in FEBS letters (14.08.2012)
Published in FEBS letters (14.08.2012)
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Journal Article
BRCA1 frameshift variants leading to extended incorrect protein C termini
Nepomuceno, Thales C., Foo, Tzeh Keong, Richardson, Marcy E., Ranola, John Michael O., Weyandt, Jamie, Varga, Matthew J., Alarcon, Amaya, Gutierrez, Diana, von Wachenfeldt, Anna, Eriksson, Daniel, Kim, Raymond, Armel, Susan, Iversen, Edwin, Couch, Fergus J., Borg, Åke, Xia, Bing, Carvalho, Marcelo A., Monteiro, Alvaro N.A.
Published in HGG advances (18.07.2024)
Published in HGG advances (18.07.2024)
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Journal Article
Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis
CARVALHO, Marcelo A, MARSILLAC, Sylvia M, BAUMBACH, Lisa, SUTPHEN, Rebecca, PICKARD-BRZOSOWICZ, Jennifer L, NATHANSON, Katherine L, SALI, Andrej, GOLDGAR, David, COUCH, Fergus J, RADICE, Paolo, MONTEIRO, Alvaro N. A, KARCHIN, Rachel, MANOUKIAN, Siranoush, GRIST, Scott, SWABY, Ramona F, URMENYI, Turan P, RONDINELLI, Edson, SILVA, Rosane, GAYOL, Luis
Published in Cancer research (Chicago, Ill.) (15.02.2007)
Published in Cancer research (Chicago, Ill.) (15.02.2007)
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Journal Article
BRCA1 frameshift variants leading to extended incorrect protein C termini
Nepomuceno, Thales C., Foo, Tzeh Keong, Richardson, Marcy E., Ranola, John Michael O., Weyandt, Jamie, Varga, Matthew J., Alarcon, Amaya, Gutierrez, Diana, von Wachenfeldt, Anna, Eriksson, Daniel, Kim, Raymond, Armel, Susan, Iversen, Edwin, Couch, Fergus J., Borg, Åke, Xia, Bing, Carvalho, Marcelo A., Monteiro, Alvaro N.A.
Published in HGG advances (12.10.2023)
Published in HGG advances (12.10.2023)
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Journal Article
Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage
Freeman, Alyson K., Dapic, Virna, Monteiro, Alvaro N.A.
Published in Cell cycle (Georgetown, Tex.) (15.02.2010)
Published in Cell cycle (Georgetown, Tex.) (15.02.2010)
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Journal Article
BRCA1 Protein and Nucleolin Colocalize in Breast Carcinoma Tissue and Cancer Cell Lines
Tulchin, Natalie, Chambon, Monique, Juan, Gloria, Dikman, Steven, Strauchen, James, Ornstein, Leonard, Billack, Blase, Woods, Nicholas T, Monteiro, Alvaro N.A
Published in The American journal of pathology (01.03.2010)
Published in The American journal of pathology (01.03.2010)
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Journal Article
BRCA1 can stimulate gene transcription by a unique mechanism
Nadeau, Guy, Boufaied, Nadia, Moisan, Annie, Lemieux, Karine M, Cayanan, Charmagne, Monteiro, Alvaro N A, Gaudreau, Luc
Published in EMBO reports (01.09.2000)
Published in EMBO reports (01.09.2000)
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