Structural Determinants of Ligand Binding Selectivity between the Peroxisome Proliferator-Activated Receptors
Xu, H. Eric, Lambert, Millard H., Montana, Valerie G., Plunket, Kelli D., Moore, Linda B., Collins, Jon L., Oplinger, Jeffery A., Kliewer, Steven A., Gampe, Robert T., McKee, David D., Moore, John T., Willson, Timothy M.
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2001)
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Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix
Gampe, Jr, R T, Montana, V G, Lambert, M H, Wisely, G B, Milburn, M V, Xu, H E
Published in Genes & development (01.09.2000)
Published in Genes & development (01.09.2000)
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Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition
Bledsoe, Randy K., Montana, Valerie G., Stanley, Thomas B., Delves, Chris J., Apolito, Christopher J., McKee, David D., Consler, Thomas G., Parks, Derek J., Stewart, Eugene L., Willson, Timothy M., Lambert, Millard H., Moore, John T., Pearce, Kenneth H., Xu, H.Eric
Published in Cell (12.07.2002)
Published in Cell (12.07.2002)
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Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPAR α
Xu, H. Eric, Stanley, Thomas B, Montana, Valerie G, Lambert, Millard H, Shearer, Barry G, Cobb, Jeffery E, McKee, David D, Galardi, Cristin M, Plunket, Kelli D, Nolte, Robert T, Parks, Derek J, Moore, John T, Kliewer, Steven A, Willson, Timothy M, Stimmel, Julie B
Published in Nature (London) (14.02.2002)
Published in Nature (London) (14.02.2002)
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Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors
Gampe, Robert T., Montana, Valerie G., Lambert, Millard H., Miller, Aaron B., Bledsoe, Randy K., Milburn, Michael V., Kliewer, Steven A., Willson, Timothy M., Xu, H.Eric
Published in Molecular cell (01.03.2000)
Published in Molecular cell (01.03.2000)
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Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors
Xu, H.Eric, Lambert, Millard H, Montana, Valerie G, Parks, Derek J, Blanchard, Steven G, Brown, Peter J, Sternbach, Daniel D, Lehmann, Jürgen M, Wisely, G.Bruce, Willson, Timothy M, Kliewer, Steven A, Milburn, Michael V
Published in Molecular cell (01.03.1999)
Published in Molecular cell (01.03.1999)
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Crystal Structure of the Catalytic Domain of the Human Cell Cycle Control Phosphatase, Cdc25A
Fauman, Eric B., Cogswell, John P., Lovejoy, Brett, Rocque, Warren J., Holmes, William, Montana, Valerie G., Piwnica-Worms, Helen, Rink, Martin J., Saper, Mark A.
Published in Cell (15.05.1998)
Published in Cell (15.05.1998)
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Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity
Sznaidman, Marcos L., Haffner, Curt D., Maloney, Patrick R., Fivush, Adam, Chao, Esther, Goreham, Donna, Sierra, Michael L., LeGrumelec, Christelle, Xu, H.Eric, Montana, Valerie G., Lambert, Millard H., Willson, Timothy M., Oliver, William R., Sternbach, Daniel D.
Published in Bioorganic & medicinal chemistry letters (05.05.2003)
Published in Bioorganic & medicinal chemistry letters (05.05.2003)
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Structure-Based Design of Potent Retinoid X Receptor α Agonists
Haffner, Curt D., Lenhard, James M., Miller, Aaron B., McDougald, Darryl L., Dwornik, Kate, Ittoop, Olivia R., Gampe, Robert T., Xu, H. Eric, Blanchard, Steve, Montana, Valerie G., Consler, Tom G., Bledsoe, Randy K., Ayscue, Andrea, Croom, Dallas
Published in Journal of medicinal chemistry (08.04.2004)
Published in Journal of medicinal chemistry (08.04.2004)
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Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
Gampe, Jr, R T, Montana, V G, Lambert, M H, Miller, A B, Bledsoe, R K, Milburn, M V, Kliewer, S A, Willson, T M, Xu, H E
Published in Molecular cell (01.03.2000)
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Published in Molecular cell (01.03.2000)
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Subtype Specific Effects of Peroxisome Proliferator-Activated Receptor Ligands on Corepressor Affinity
Stanley, Thomas B, Leesnitzer, Lisa M, Montana, Valerie G, Galardi, Cristin M, Lambert, Millard H, Holt, Jason A, Xu, H. Eric, Moore, Linda B, Blanchard, Steven G, Stimmel, Julie B
Published in Biochemistry (Easton) (12.08.2003)
Published in Biochemistry (Easton) (12.08.2003)
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Alteration of a Single Amino Acid in Peroxisome Proliferator-Activated Receptor-α (PPARα) Generates a PPARδ Phenotype
Takada, Ichiro, Yu, Ruth T, Xu, H. Eric, Lambert, Millard H, Montana, Valerie G, Kliewer, Steven A, Evans, Ronald M, Umesono, Kazuhiko
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2000)
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2000)
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