Search Results - "Mondelli, Valeria"
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Can high-intensity interval training improve physical and mental health outcomes? A meta-review of 33 systematic reviews across the lifespan
Published in Journal of sports sciences (16.02.2020)“…High-intensity-interval-training (HIIT) has been suggested to have beneficial effects in multiple populations across individual systematic reviews, although…”
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Markers of central inflammation in major depressive disorder: A systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission tomography and post-mortem brain tissue
Published in Brain, behavior, and immunity (01.10.2019)“…•Patients depression have higher CSF levels of IL-6 and TNF-α than controls.•Patients with depression have higher PET TSPO expression in different brain…”
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Heart rate variability (HRV) as a way to understand associations between the autonomic nervous system (ANS) and affective states: A critical review of the literature
Published in International journal of psychophysiology (01.10.2023)“…Evidence suggests affective disorders such as depression and bipolar disorder are characterised by dysregulated autonomic nervous system (ANS) activity. These…”
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Ketamine’s effect on inflammation and kynurenine pathway in depression: A systematic review
Published in Journal of psychopharmacology (Oxford) (01.08.2021)“…Background: Ketamine is a novel rapid-acting antidepressant with high efficacy in treatment-resistant patients. Its exact therapeutic mechanisms of action are…”
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Effects of psychotropic drugs on inflammation: consequence or mediator of therapeutic effects in psychiatric treatment?
Published in Psychopharmacology (01.05.2016)“…Rationale Current psychotropic medications have been shown to modulate immune activation. However, the effects of individual psychotropic agents on the immune…”
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Genetic Contributions of Inflammation to Depression
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2017)“…This paper describes the effects of immune genes genetic variants and mRNA expression on depression's risk, severity, and response to antidepressant treatment,…”
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Inflammation in cancer and depression: a starring role for the kynurenine pathway
Published in Psychopharmacology (01.10.2019)“…Depression is a common comorbidity in cancer cases, but this is not only due to the emotional distress of having a life-threatening disease. A common…”
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Cortisol and development of depression in adolescence and young adulthood – a systematic review and meta-analysis
Published in Psychoneuroendocrinology (01.02.2022)“…Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been implicated in the development of major depressive disorder (MDD) in adulthood. Less…”
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Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2021)“…This study aimed to investigate the role of baseline levels of peripheral inflammation when testing the efficacy of antidepressant augmentation with…”
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The HPA axis in bipolar disorder: Systematic review and meta-analysis
Published in Psychoneuroendocrinology (01.01.2016)“…•Bipolar disorder is associated with state and trait hyperactivity of the HPA axis.•Abnormalities of glucocorticoid signaling are found in several key brain…”
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Associations Between Non-neurological Autoimmune Disorders and Psychosis: A Meta-analysis
Published in Biological psychiatry (1969) (01.01.2019)“…A relationship between non-neurological autoimmune (NNAI) disorders and psychosis has been widely reported but not yet subjected to meta-analysis. We conducted…”
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Cortisol and inflammatory biomarker levels in youths with attention deficit hyperactivity disorder (ADHD): evidence from a systematic review with meta-analysis
Published in Translational psychiatry (19.08.2021)“…Several studies reported abnormal cortisol and inflammatory biomarker levels in youths with attention deficit hyperactivity disorder (ADHD), but the results…”
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Brain microglia in psychiatric disorders
Published in The Lancet. Psychiatry (01.07.2017)“…The role of immune activation in psychiatric disorders has attracted considerable attention over the past two decades, contributing to the rise of a new era…”
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High-potency cannabis and the risk of psychosis
Published in British journal of psychiatry (01.12.2009)“…People who use cannabis have an increased risk of psychosis, an effect attributed to the active ingredient Delta 9-tetrahydrocannabinol (Delta 9-THC). There…”
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HPA axis and aging in depression: Systematic review and meta-analysis
Published in Psychoneuroendocrinology (01.03.2014)“…One of the most consistent findings in the biology of depression is an altered activity of the hypothalamic–pituitary–adrenal (HPA) axis. However, data…”
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Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
Published in Translational psychiatry (23.07.2020)“…The mRNA expression signatures associated with the ‘pro-inflammatory’ phenotype of depression, and the differential signatures associated with depression…”
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Reply to Drs Munkholm and Paludan-Müller’s comment on our paper “Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial”
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2021)
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HPA axis response to social stress is attenuated in schizophrenia but normal in depression: Evidence from a meta-analysis of existing studies
Published in Neuroscience and biobehavioral reviews (01.11.2014)“…We conducted a meta-analysis to investigate the HPA axis response to social stress in studies that used the Trier Social Stress Test (TSST), or comparable…”
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Predicting the risk of depression among adolescents in Nepal using a model developed in Brazil: the IDEA Project
Published in European child & adolescent psychiatry (01.02.2021)“…The burden of adolescent depression is high in low- and middle-income countries (LMICs), yet research into prevention is lacking. Development and validation of…”
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The Role of Peripheral Inflammation in Clinical Outcome and Brain Imaging Abnormalities in Psychosis: A Systematic Review
Published in Frontiers in psychiatry (19.02.2021)“…Promising research investigating the association between inflammatory biomarkers and response to antipsychotic and/or adjunctive therapy, observed by…”
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