Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics
Hernandez, J Javier, Pryszlak, Michael, Smith, Lindsay, Yanchus, Connor, Kurji, Naheed, Shahani, Vijay M, Molinski, Steven V
Published in Frontiers in oncology (14.11.2017)
Published in Frontiers in oncology (14.11.2017)
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Journal Article
Mammalian multidrug-resistance proteins (MRPs)
Slot, Andrew J, Molinski, Steven V, Cole, Susan P C
Published in Essays in biochemistry (07.09.2011)
Published in Essays in biochemistry (07.09.2011)
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Journal Article
Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue
Molinski, Steven V, Ahmadi, Saumel, Ip, Wan, Ouyang, Hong, Villella, Adriana, Miller, John P, Lee, Po‐Shun, Kulleperuma, Kethika, Du, Kai, Di Paola, Michelle, Eckford, Paul DW, Laselva, Onofrio, Huan, Ling Jun, Wellhauser, Leigh, Li, Ellen, Ray, Peter N, Pomès, Régis, Moraes, Theo J, Gonska, Tanja, Ratjen, Felix, Bear, Christine E
Published in EMBO molecular medicine (01.09.2017)
Published in EMBO molecular medicine (01.09.2017)
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Journal Article
Comprehensive mapping of cystic fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site
Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, Andreas
Published in Proteins, structure, function, and bioinformatics (01.08.2018)
Published in Proteins, structure, function, and bioinformatics (01.08.2018)
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Journal Article
The Antiretroviral Agent Nelfinavir Mesylate: A Potential Therapy for Systemic Sclerosis
Sanchez, Cecilia G, Molinski, Steven V, Gongora, Rafael, Sosulski, Meredith, Fuselier, Taylor, MacKinnon, Stephen S, Mondal, Debasis, Lasky, Joseph A
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2018)
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Journal Article
Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity
Malik, Firhan A, Meissner, Anja, Semenkov, Illya, Molinski, Steven, Pasyk, Stan, Ahmadi, Saumel, Bui, Hai H, Bear, Christine E, Lidington, Darcy, Bolz, Steffen-Sebastian
Published in PloS one (16.06.2015)
Published in PloS one (16.06.2015)
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Journal Article
Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia
Ahmadi, Saumel, Bozoky, Zoltan, Di Paola, Michelle, Xia, Sunny, Li, Canhui, Wong, Amy P., Wellhauser, Leigh, Molinski, Steven V., Ip, Wan, Ouyang, Hong, Avolio, Julie, Forman-Kay, Julie D., Ratjen, Felix, Hirota, Jeremy A., Rommens, Johanna, Rossant, Janet, Gonska, Tanja, Moraes, Theo J., Bear, Christine E.
Published in Npj genomic medicine (14.04.2017)
Published in Npj genomic medicine (14.04.2017)
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Genetic, cell biological, and clinical interrogation of the CFTR mutation c.3700 A>G (p.Ile1234Val) informs strategies for future medical intervention
Molinski, Steven V., Gonska, Tanja, Huan, Ling Jun, Baskin, Berivan, Janahi, Ibrahim A., Ray, Peter N., Bear, Christine E.
Published in Genetics in medicine (01.08.2014)
Published in Genetics in medicine (01.08.2014)
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Journal Article
Computational proteome-wide screening predicts neurotoxic drug-protein interactome for the investigational analgesic BIA 10-2474
Molinski, Steven V., Shahani, Vijay M., MacKinnon, Stephen S., Morayniss, Leonard D., Laforet, Marcon, Woollard, Geoffrey, Kurji, Naheed, Sanchez, Cecilia G., Wodak, Shoshana J., Windemuth, Andreas
Published in Biochemical and biophysical research communications (29.01.2017)
Published in Biochemical and biophysical research communications (29.01.2017)
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Journal Article
Identification and validation of hits from high throughput screens for CFTR modulators
Pasyk, Stan, Molinski, Steven, Yu, Wilson, Eckford, Paul D W, Bear, Christine E
Published in Current pharmaceutical design (01.02.2012)
Published in Current pharmaceutical design (01.02.2012)
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Journal Article
Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains
Laselva, Onofrio, Molinski, Steven, Casavola, Valeria, Bear, Christine E
Published in Molecular pharmacology (01.06.2018)
Published in Molecular pharmacology (01.06.2018)
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Journal Article
Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells
Aslam, Rukhsana, Kim, Michael, Speck, Edwin R., Seetanah, Arjuna Contram, Molinski, Steven, Freedman, John, Semple, John W.
Published in Transfusion (Philadelphia, Pa.) (01.11.2007)
Published in Transfusion (Philadelphia, Pa.) (01.11.2007)
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Journal Article
VX-809 and Related Corrector Compounds Exhibit Secondary Activity Stabilizing Active F508del-CFTR after Its Partial Rescue to the Cell Surface
Eckford, Paul D.W., Ramjeesingh, Mohabir, Molinski, Steven, Pasyk, Stan, Dekkers, Johanna F., Li, Canhui, Ahmadi, Saumel, Ip, Wan, Chung, Timothy E., Du, Kai, Yeger, Herman, Beekman, Jeffrey, Gonska, Tanja, Bear, Christine E.
Published in Chemistry & biology (22.05.2014)
Published in Chemistry & biology (22.05.2014)
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Journal Article
The Antiretroviral Agent Nelfinavir Mesylate
Sanchez, Cecilia G., Molinski, Steven V., Gongora, Rafael, Sosulski, Meredith, Fuselier, Taylor, MacKinnon, Stephen S., Mondal, Debasis, Lasky, Joseph A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2018)
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Journal Article
Cover Image, Volume 86, Issue 8
Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, Andreas
Published in Proteins, structure, function, and bioinformatics (01.08.2018)
Published in Proteins, structure, function, and bioinformatics (01.08.2018)
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